Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Stxbp1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes STXBP1
- Mouse genes Stxbp1
- Rat genes Stxbp1
- Zfish genes stxbp1a,stxbp1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stxbp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Stxbp1	IPI	UniProtKB:P61765	Rat	PMID:17442889\|RGD:2312426
Molecular Function	GO:0060090	molecular adaptor activity	Stxbp1	EXP		Rat	PMID:21193638\|RGD:13432275
Molecular Function	GO:0043274	phospholipase binding	Stxbp1	IDA		Rat	PMID:14744865\|RGD:12904032
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:P05067	Human	PMID:16049941
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:O00635	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:O75558	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q8N4C7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:O00635	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:O75558	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:P11142	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:P50222	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q0VDD7	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q13190	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q8N4C7	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q16623	Human	PMID:26635000
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:O00635	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:P28482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q13190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q6IPU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q8N0Z3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q8N4C7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:Q96C24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:O75376	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:P21917	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	STXBP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P31423	Mouse	MGI:MGI:4366182\|PMID:19822743
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	PR:Q64704-1	Mouse	PMID:7598732
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	PR:Q9DBZ9	Mouse	PMID:23791195
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	PR:Q64704-2	Mouse	PMID:7598732
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	PR:Q9R0Q1	Mouse	PMID:12590134
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P32851	Rat	PMID:10746715\|RGD:8553704
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P32851	Rat	PMID:12093152\|RGD:730238
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P61265	Rat	PMID:12093152\|RGD:730238
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	RGD:69329	Rat	PMID:12963086\|RGD:1598430
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P32851	Rat	PMID:17301226\|RGD:13432352
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:O70441	Rat	PMID:17442889\|RGD:2312426
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P50279	Rat	PMID:17442889\|RGD:2312426
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:Q08849	Rat	PMID:17442889\|RGD:2312426
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:Q63537	Rat	PMID:17442889\|RGD:2312426
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:Q91ZS3-2	Rat	PMID:17442889\|RGD:2312426
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:Q9BRK5-5	Rat	PMID:17442889\|RGD:2312426
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P32851	Rat	PMID:18337752\|RGD:8553871
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	RGD:69430	Rat	PMID:19255244\|RGD:2311128
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P32851	Rat	PMID:21193638\|RGD:13432275
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P70452	Rat	PMID:21193638\|RGD:13432275
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P63012	Rat	PMID:21689256\|RGD:14390056
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P32851	Rat	PMID:26359495\|RGD:10412295
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:P32851	Rat	PMID:26876096\|RGD:11573385
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:O35430	Rat	PMID:9395480\|RGD:727250
Molecular Function	GO:0005515	protein binding	Stxbp1	IPI	UniProtKB:O35431	Rat	PMID:9395480\|RGD:727250
Molecular Function	GO:0019904	protein domain specific binding	Stxbp1	IDA		Rat	PMID:19255244\|RGD:2311128
Molecular Function	GO:0019901	protein kinase binding	Stxbp1	IPI	RGD:70514	Rat	PMID:12963086\|RGD:1598430
Molecular Function	GO:0003723	RNA binding	STXBP1	HDA		Human	PMID:22658674
Molecular Function	GO:0000149	SNARE binding	Stxbp1	IDA		Rat	PMID:18201107\|RGD:2311133
Molecular Function	GO:0000149	SNARE binding	Stxbp1	IDA		Rat	PMID:19255244\|RGD:2311128
Molecular Function	GO:0019905	syntaxin binding	STXBP1	IPI	UniProtKB:P32856	Human	PMID:12773094
Molecular Function	GO:0019905	syntaxin binding	Stxbp1	IDA		Rat	PMID:12506202\|RGD:629534
Molecular Function	GO:0017075	syntaxin-1 binding	STXBP1	IPI	UniProtKB:Q16623	Human	PMID:12730201
Molecular Function	GO:0017075	syntaxin-1 binding	STXBP1	IPI	UniProtKB:Q16623	Human	PMID:19748891
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp1	IDA		Mouse	MGI:MGI:3803800\|PMID:18703708
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp1	IPI	PR:O35526	Mouse	PMID:7890599
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp1	IDA		Rat	PMID:12093152\|RGD:730238
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp1	IDA		Rat	PMID:7553862\|RGD:70701
Cellular Component	GO:0030424	axon	Stxbp1	IDA		Mouse	MGI:MGI:5819336\|PMID:23821748
Cellular Component	GO:0030424	axon	Stxbp1	IDA		Rat	PMID:15869823\|RGD:12903987
Cellular Component	GO:0005737	cytoplasm	Stxbp1	IDA		Rat	PMID:17442889\|RGD:2312426
Cellular Component	GO:0005856	cytoskeleton	Stxbp1	IDA		Rat	PMID:15869823\|RGD:12903987
Cellular Component	GO:0005829	cytosol	STXBP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	STXBP1	HDA		Human	PMID:19056867
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	Stxbp1	IDA		Mouse	PMID:24590174
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	Stxbp1	IMP		Mouse	PMID:24590174
Cellular Component	GO:0098978	glutamatergic synapse	Stxbp1	IDA		Mouse	PMID:17110441
Cellular Component	GO:0098978	glutamatergic synapse	Stxbp1	IMP		Mouse	PMID:17110441
Cellular Component	GO:0005739	mitochondrion	Stxbp1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0043209	myelin sheath	Stxbp1	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0005654	nucleoplasm	STXBP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Stxbp1	IDA		Rat	PMID:15869823\|RGD:12903987
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Stxbp1	IDA		Mouse	PMID:32494600
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Stxbp1	IDA		Rat	PMID:15869823\|RGD:12903987
Cellular Component	GO:0045335	phagocytic vesicle	Stxbp1	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005886	plasma membrane	STXBP1	IDA		Human	PMID:12773094
Cellular Component	GO:0005886	plasma membrane	Stxbp1	IDA		Mouse	MGI:MGI:5819336\|PMID:23821748
Cellular Component	GO:0005886	plasma membrane	Stxbp1	IDA		Rat	PMID:17442889\|RGD:2312426
Cellular Component	GO:0005886	plasma membrane	Stxbp1	IDA		Rat	PMID:12093152\|RGD:730238
Cellular Component	GO:0031091	platelet alpha granule	STXBP1	IDA		Human	PMID:12773094
Cellular Component	GO:0098794	postsynapse	Stxbp1	IDA		Rat	PMID:15869823\|RGD:12903987
Cellular Component	GO:0098793	presynapse	Stxbp1	IDA		Rat	PMID:15869823\|RGD:12903987
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Stxbp1	IDA		Mouse	PMID:32494600
Cellular Component	GO:0048787	presynaptic active zone membrane	Stxbp1	IDA		Mouse	MGI:MGI:5819336\|PMID:23821748
Cellular Component	GO:0099523	presynaptic cytosol	Stxbp1	IMP		Mouse	PMID:24590174
Cellular Component	GO:0099523	presynaptic cytosol	Stxbp1	IDA		Mouse	PMID:24590174
Cellular Component	GO:0032991	protein-containing complex	Stxbp1	IDA		Rat	PMID:19255244\|RGD:2311128
Cellular Component	GO:0043195	terminal bouton	Stxbp1	HDA		Rat	PMID:24876496\|RGD:10047219
Biological Process	GO:0007412	axon target recognition	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:15182301
Biological Process	GO:0071346	cellular response to type II interferon	Stxbp1	IDA		Mouse	PMID:19144319
Biological Process	GO:0003006	developmental process involved in reproduction	Stxbp1	IMP		Rat	PMID:16951547\|RGD:12904030
Biological Process	GO:0051649	establishment of localization in cell	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:11545717
Biological Process	GO:0006887	exocytosis	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:11545717
Biological Process	GO:0060292	long-term synaptic depression	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:17110441
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:15255974
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	Stxbp1	IDA		Rat	PMID:12093152\|RGD:730238
Biological Process	GO:0032229	negative regulation of synaptic transmission, GABAergic	Stxbp1	IDA		Mouse	PMID:17167098
Biological Process	GO:0007274	neuromuscular synaptic transmission	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:17110441
Biological Process	GO:0051402	neuron apoptotic process	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:15255974
Biological Process	GO:0007269	neurotransmitter secretion	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:15255974
Biological Process	GO:0070527	platelet aggregation	STXBP1	IMP		Human	PMID:12773094
Biological Process	GO:0002576	platelet degranulation	STXBP1	IMP		Human	PMID:12773094
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Stxbp1	IDA		Mouse	PMID:15123626
Biological Process	GO:0045921	positive regulation of exocytosis	Stxbp1	IMP		Rat	PMID:20801887\|RGD:7242946
Biological Process	GO:1903296	positive regulation of glutamate secretion, neurotransmission	Stxbp1	IMP		Rat	PMID:16951547\|RGD:12904030
Biological Process	GO:0043306	positive regulation of mast cell degranulation	Stxbp1	IMP		Rat	PMID:23487749\|RGD:12904029
Biological Process	GO:0106022	positive regulation of vesicle docking	Stxbp1	IDA		Rat	PMID:22810233\|RGD:12903989
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	Stxbp1	IMP		Mouse	MGI:MGI:3621672\|PMID:11545717
Biological Process	GO:0072659	protein localization to plasma membrane	STXBP1	IDA		Human	PMID:17543282
Biological Process	GO:0050821	protein stabilization	Stxbp1	IDA		Rat	PMID:15935055\|RGD:8554740
Biological Process	GO:2000367	regulation of acrosomal vesicle exocytosis	STXBP1	IMP		Human	PMID:23091057
Biological Process	GO:0010807	regulation of synaptic vesicle priming	Stxbp1	IMP		Rat	PMID:19255244\|RGD:2311128
Biological Process	GO:0010807	regulation of synaptic vesicle priming	Stxbp1	IDA		Rat	PMID:21689256\|RGD:14390056
Biological Process	GO:0031338	regulation of vesicle fusion	Stxbp1	IDA		Rat	PMID:24532794\|RGD:12903988
Biological Process	GO:0032355	response to estradiol	Stxbp1	IEP		Rat	PMID:16951547\|RGD:12904030
Biological Process	GO:0035493	SNARE complex assembly	STXBP1	IMP		Human	PMID:23091057
Biological Process	GO:0016188	synaptic vesicle maturation	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:15145078
Biological Process	GO:0016082	synaptic vesicle priming	Stxbp1	IMP		Mouse	PMID:17110441
Biological Process	GO:0016082	synaptic vesicle priming	Stxbp1	IDA		Mouse	PMID:17110441
Biological Process	GO:0006904	vesicle docking involved in exocytosis	Stxbp1	IMP		Mouse	MGI:MGI:3803800\|PMID:18703708
Biological Process	GO:0006904	vesicle docking involved in exocytosis	Stxbp1	IMP	MGI:MGI:2183278	Mouse	PMID:11545717

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.