Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes STXBP2
  • Mouse genes Stxbp2
  • Rat genes Stxbp2
  • Zfish genes stxbp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Stxbp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	STXBP2	IPI	UniProtKB:O75558	Human	PMID:19804848
Molecular Function	GO:0005515	protein binding	STXBP2	IPI	UniProtKB:O75558	Human	PMID:19884660
Molecular Function	GO:0005515	protein binding	Stxbp2	IPI	PR:Q64704	Mouse	PMID:18535671
Molecular Function	GO:0005515	protein binding	Stxbp2	IPI	PR:Q00262	Mouse	PMID:18535671
Molecular Function	GO:0005515	protein binding	Stxbp2	IPI	RGD:621521	Rat	PMID:17442889|RGD:2312426
Molecular Function	GO:0019905	syntaxin binding	Stxbp2	IPI	RGD:2558	Rat	PMID:7768895|RGD:730001
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp2	IPI	PR:O35526	Mouse	PMID:7890599
Molecular Function	GO:0017075	syntaxin-1 binding	Stxbp2	IPI	RGD:69430	Rat	PMID:7768895|RGD:730001
Molecular Function	GO:0030348	syntaxin-3 binding	STXBP2	IPI	UniProtKB:Q13277	Human	PMID:18588921
Molecular Function	GO:0030348	syntaxin-3 binding	Stxbp2	IPI	PR:Q64704	Mouse	PMID:10469351
Molecular Function	GO:0030348	syntaxin-3 binding	Stxbp2	IPI	PR:Q64704	Mouse	PMID:18505797
Molecular Function	GO:0030348	syntaxin-3 binding	Stxbp2	IPI	RGD:621005	Rat	PMID:7768895|RGD:730001
Cellular Component	GO:0016324	apical plasma membrane	Stxbp2	IDA		Mouse	PMID:10469351
Cellular Component	GO:0016324	apical plasma membrane	Stxbp2	IDA		Mouse	PMID:18505797
Cellular Component	GO:0016324	apical plasma membrane	Stxbp2	IDA		Rat	PMID:22694344|RGD:7327225
Cellular Component	GO:0042582	azurophil granule	STXBP2	IDA		Human	PMID:18588921
Cellular Component	GO:0044194	cytolytic granule	STXBP2	IDA		Human	PMID:19804848
Cellular Component	GO:0005737	cytoplasm	Stxbp2	IDA		Rat	PMID:17408745|RGD:2312427
Cellular Component	GO:0005829	cytosol	STXBP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	STXBP2	IDA		Human	PMID:18588921
Cellular Component	GO:0070062	extracellular exosome	STXBP2	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	STXBP2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	STXBP2	HDA		Human	PMID:23533145
Cellular Component	GO:0030027	lamellipodium	Stxbp2	IDA		Rat	PMID:12482918|RGD:2312429
Cellular Component	GO:0045335	phagocytic vesicle	Stxbp2	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005886	plasma membrane	STXBP2	IDA		Human	PMID:18588921
Cellular Component	GO:0005886	plasma membrane	Stxbp2	IDA		Mouse	PMID:18535671
Cellular Component	GO:0005886	plasma membrane	Stxbp2	IPI	PR:Q00262	Mouse	PMID:18535671
Cellular Component	GO:0005886	plasma membrane	Stxbp2	IDA		Rat	PMID:17408745|RGD:2312427
Cellular Component	GO:0032991	protein-containing complex	Stxbp2	IDA		Rat	PMID:17442889|RGD:2312426
Cellular Component	GO:0030141	secretory granule	Stxbp2	IDA		Rat	PMID:17408745|RGD:2312427
Cellular Component	GO:0042581	specific granule	STXBP2	IDA		Human	PMID:18588921
Cellular Component	GO:0070820	tertiary granule	STXBP2	IDA		Human	PMID:18588921
Cellular Component	GO:0042589	zymogen granule membrane	Stxbp2	IDA		Mouse	PMID:18535671
Cellular Component	GO:0042589	zymogen granule membrane	Stxbp2	IPI	PR:Q64704	Mouse	PMID:18535671
Biological Process	GO:0071346	cellular response to type II interferon	Stxbp2	IDA		Mouse	PMID:19144319
Biological Process	GO:0006887	exocytosis	Stxbp2	IMP		Mouse	PMID:18505797
Biological Process	GO:0001909	leukocyte mediated cytotoxicity	STXBP2	IMP		Human	PMID:19884660
Biological Process	GO:0043312	neutrophil degranulation	STXBP2	IEP		Human	PMID:18588921
Biological Process	GO:0043306	positive regulation of mast cell degranulation	Stxbp2	IMP		Rat	PMID:23487749|RGD:12904029
Biological Process	GO:0043304	regulation of mast cell degranulation	Stxbp2	IMP		Rat	PMID:12482918|RGD:2312429
Biological Process	GO:0010447	response to acidic pH	Stxbp2	IEP		Rat	PMID:15240346|RGD:2312428

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern