Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Sulf2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SULF2
- Mouse genes Sulf2
- Rat genes Sulf2
- Zfish genes sulf2a,sulf2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sulf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004065	arylsulfatase activity	SULF2	IDA		Human	PMID:12368295
Molecular Function	GO:0004065	arylsulfatase activity	SULF2	IMP		Human	PMID:19520866
Molecular Function	GO:0004065	arylsulfatase activity	SULF2	IMP		Human	PMID:30788513
Molecular Function	GO:0004065	arylsulfatase activity	SULF2	IMP		Human	PMID:35294879
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	SULF2	IDA		Human	PMID:18687675
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	SULF2	IMP		Human	PMID:19520866
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	SULF2	IMP		Human	PMID:30788513
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	SULF2	IMP		Human	PMID:35294879
Molecular Function	GO:0008449	N-acetylglucosamine-6-sulfatase activity	Sulf2	IMP		Mouse	MGI:MGI:5306289\|PMID:18687675
Cellular Component	GO:0009986	cell surface	SULF2	IDA		Human	PMID:12368295
Cellular Component	GO:0009986	cell surface	SULF2	IDA		Human	PMID:18687675
Cellular Component	GO:0009986	cell surface	SULF2	IDA		Human	PMID:19520866
Cellular Component	GO:0009986	cell surface	SULF2	IDA		Human	PMID:35294879
Cellular Component	GO:0005783	endoplasmic reticulum	SULF2	IDA		Human	PMID:18687675
Cellular Component	GO:0005576	extracellular region	SULF2	IMP		Human	PMID:30788513
Cellular Component	GO:0005576	extracellular region	SULF2	IMP		Human	PMID:35294879
Cellular Component	GO:0005886	plasma membrane	Sulf2	IDA		Mouse	MGI:MGI:5306737\|PMID:21719793
Biological Process	GO:0060348	bone development	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:3769052\|PMID:17593974
Biological Process	GO:0051216	cartilage development	Sulf2	IMP		Mouse	MGI:MGI:5306560\|PMID:20479257
Biological Process	GO:0002063	chondrocyte development	Sulf2	IMP		Mouse	MGI:MGI:5306560\|PMID:20479257
Biological Process	GO:0048706	embryonic skeletal system development	Sulf2	IGI	UniProtKB:Q8CFG0	Mouse	MGI:MGI:3771123\|PMID:18213582
Biological Process	GO:0010669	epithelial structure maintenance	sulf2a	IGI	ZFIN:ZDB-GENE-030131-9242,ZFIN:ZDB-GENE-030131-775	Zfish	PMID:31428635
Biological Process	GO:0010669	epithelial structure maintenance	sulf2b	IMP	ZFIN:ZDB-MRPHLNO-200123-2	Zfish	PMID:31428635
Biological Process	GO:0010669	epithelial structure maintenance	sulf2a	IMP	ZFIN:ZDB-MRPHLNO-200123-1	Zfish	PMID:31428635
Biological Process	GO:0010669	epithelial structure maintenance	sulf2b	IGI	ZFIN:ZDB-GENE-030131-9242,ZFIN:ZDB-GENE-040426-759	Zfish	PMID:31428635
Biological Process	GO:0014846	esophagus smooth muscle contraction	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:3722747\|PMID:17720696
Biological Process	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	Sulf2	IDA		Mouse	MGI:MGI:3722747\|PMID:17720696
Biological Process	GO:0032836	glomerular basement membrane development	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:5306737\|PMID:21719793
Biological Process	GO:0003094	glomerular filtration	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:5306737\|PMID:21719793
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	SULF2	IDA		Human	PMID:18687675
Biological Process	GO:0030201	heparan sulfate proteoglycan metabolic process	Sulf2	IMP		Mouse	MGI:MGI:5306289\|PMID:18687675
Biological Process	GO:0060384	innervation	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:3722747\|PMID:17720696
Biological Process	GO:0001822	kidney development	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:3769052\|PMID:17593974
Biological Process	GO:0097421	liver regeneration	Sulf2	IMP	MGI:MGI:3587954	Mouse	PMID:23740243
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:5306737\|PMID:21719793
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:3769052\|PMID:17593974
Biological Process	GO:0014003	oligodendrocyte development	sulf2a	IMP	ZFIN:ZDB-GENO-211201-1	Zfish	PMID:33420239
Biological Process	GO:0014003	oligodendrocyte development	sulf2a	IMP	ZFIN:ZDB-MRPHLNO-210215-1	Zfish	PMID:33420239
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Sulf2	IMP	MGI:MGI:3587954	Mouse	PMID:23740243
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	Sulf2	IGI	UniProtKB:Q8K007	Mouse	MGI:MGI:5306737\|PMID:21719793
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	SULF2	IDA		Human	PMID:19520866
Biological Process	GO:2000345	regulation of hepatocyte proliferation	Sulf2	IMP	MGI:MGI:3587954	Mouse	PMID:23740243
Biological Process	GO:0009611	response to wounding	Sulf2	IMP	MGI:MGI:3587954	Mouse	PMID:23740243
Biological Process	GO:0021514	ventral spinal cord interneuron differentiation	sulf2a	IMP	ZFIN:ZDB-GENO-211201-1	Zfish	PMID:33420239
Biological Process	GO:0021514	ventral spinal cord interneuron differentiation	sulf2a	IMP	ZFIN:ZDB-MRPHLNO-210215-1	Zfish	PMID:33420239

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 06/12/2024 MGI 6.13

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.