Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SUN1
  • Mouse genes Sun1
  • Rat genes Sun1
  • Zfish genes sun1a,sun1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sun1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140444	cytoskeleton-nuclear membrane anchor activity	SUN1	IDA		Human	PMID:18396275
Molecular Function	GO:0005521	lamin binding	Sun1	IDA		Mouse	MGI:MGI:4441241|PMID:19933576
Molecular Function	GO:0005515	protein binding	SUN1	IPI	UniProtKB:Q6ZMZ3	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SUN1	IPI	UniProtKB:Q8NF91	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SUN1	IPI	UniProtKB:Q8WXH0	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SUN1	IPI	UniProtKB:Q8NF91-1	Human	PMID:22632968
Molecular Function	GO:0005515	protein binding	SUN1	IPI	UniProtKB:Q8WXH0-1	Human	PMID:22632968
Molecular Function	GO:0005515	protein binding	SUN1	IPI	UniProtKB:P61165	Human	PMID:28716842
Molecular Function	GO:0005515	protein binding	Sun1	IPI	UniProtKB:P50402|UniProtKB:Q8WXH0-4	Mouse	MGI:MGI:4441241|PMID:19933576
Molecular Function	GO:0005515	protein binding	Sun1	IPI	UniProtKB:Q8C0V1	Mouse	MGI:MGI:5545837|PMID:24413433
Molecular Function	GO:0005515	protein binding	Sun1	IPI	UniProtKB:Q80VJ8	Mouse	MGI:MGI:5448795|PMID:22826121
Molecular Function	GO:0005515	protein binding	Sun1	IPI	UniProtKB:Q60664	Mouse	MGI:MGI:6415450|PMID:29878215
Molecular Function	GO:0005515	protein binding	Sun1	IPI	UniProtKB:O08579|UniProtKB:P02545|UniProtKB:Q8WXH0-4|UniProtKB:Q8WXH0-5	Mouse	MGI:MGI:4441241|PMID:19933576
Molecular Function	GO:0005515	protein binding	Sun1	IPI	PR:Q9QZE7	Mouse	PMID:12036294
Molecular Function	GO:0005515	protein binding	Sun1	IPI	PR:Q6ZWR6	Mouse	PMID:16079285
Molecular Function	GO:0005515	protein binding	Sun1	IPI	PR:P48678	Mouse	PMID:16380439
Cellular Component	GO:0000781	chromosome, telomeric region	Sun1	IDA		Mouse	PMID:28031483
Cellular Component	GO:0005737	cytoplasm	Sun1	IDA		Mouse	PMID:12036294
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SUN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0034993	meiotic nuclear membrane microtubule tethering complex	SUN1	IDA		Human	PMID:18396275
Cellular Component	GO:0016020	membrane	Sun1	IDA		Mouse	PMID:16380439
Cellular Component	GO:0005635	nuclear envelope	SUN1	IMP		Human	PMID:21610090
Cellular Component	GO:0005635	nuclear envelope	SUN1	IDA		Human	PMID:19933576
Cellular Component	GO:0005635	nuclear envelope	Sun1	IDA		Mouse	PMID:24062341
Cellular Component	GO:0005635	nuclear envelope	Sun1	IDA		Mouse	PMID:16380439
Cellular Component	GO:0005635	nuclear envelope	Sun1	IDA		Mouse	PMID:30718482
Cellular Component	GO:0005635	nuclear envelope	Sun1	IDA		Mouse	PMID:16079285
Cellular Component	GO:0005637	nuclear inner membrane	Sun1	IDA		Mouse	PMID:16380439
Cellular Component	GO:0031965	nuclear membrane	SUN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Sun1	IDA		Mouse	PMID:12036294
Cellular Component	GO:0005634	nucleus	Sun1	IDA		Rat	PMID:24036726|RGD:10003162
Biological Process	GO:0051642	centrosome localization	Sun1	IMP		Mouse	MGI:MGI:4412315|PMID:19874786
Biological Process	GO:0007129	homologous chromosome pairing at meiosis	Sun1	IMP	MGI:MGI:3715140	Mouse	PMID:24589552
Biological Process	GO:0070197	meiotic attachment of telomere to nuclear envelope	Sun1	IMP		Mouse	MGI:MGI:5573020|PMID:24586178
Biological Process	GO:0070197	meiotic attachment of telomere to nuclear envelope	Sun1	IMP	MGI:MGI:6362937	Mouse	PMID:30718482
Biological Process	GO:0090292	nuclear matrix anchoring at nuclear membrane	SUN1	IDA		Human	PMID:18396275
Biological Process	GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	Sun1	IMP		Mouse	MGI:MGI:4412315|PMID:19874786
Biological Process	GO:0001503	ossification	Sun1	IEP		Rat	PMID:24036726|RGD:10003162
Biological Process	GO:0009612	response to mechanical stimulus	Sun1	IEP		Rat	PMID:24036726|RGD:10003162

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern