Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SUPT5H
  • Mouse genes Supt5
  • Rat genes Supt5h
  • Zfish genes supt5h
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Supt5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Supt5	IDA		Mouse	PMID:21670248
Molecular Function	GO:0003677	DNA binding	supt5h	IDA		Zfish	PMID:19742326
Molecular Function	GO:0019899	enzyme binding	SUPT5H	IPI	UniProtKB:P24928	Human	PMID:10075709
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P24928	Human	PMID:10075709
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:10075709
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P62937	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P50613	Human	PMID:16327805
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:17404243
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:Q5EP34	Human	PMID:21715506
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:Q13526	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:O60318	Human	PMID:23652018
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P24928	Human	PMID:24814348
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P24928	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:25502805
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P24928	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:A5PJW8	Human	PMID:26789250
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:G3MZY8	Human	PMID:26789250
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:26789250
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:A5PJW8	Human	PMID:28892040
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	SUPT5H	IPI	UniProtKB:Q13526	Human	PMID:32296183
Molecular Function	GO:0046982	protein heterodimerization activity	SUPT5H	IPI	UniProtKB:P63272	Human	PMID:9450929
Molecular Function	GO:0003723	RNA binding	SUPT5H	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SUPT5H	HDA		Human	PMID:22681889
Cellular Component	GO:0032044	DSIF complex	SUPT5H	IPI		Human	PMID:19860741
Cellular Component	GO:0032044	DSIF complex	SUPT5H	IDA		Human	PMID:9450929
Cellular Component	GO:0005654	nucleoplasm	SUPT5H	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SUPT5H	IDA		Human	PMID:10075709
Cellular Component	GO:0005634	nucleus	SUPT5H	IDA		Human	PMID:9450929
Cellular Component	GO:0005634	nucleus	supt5h	IDA		Zfish	PMID:18978947
Biological Process	GO:0021954	central nervous system neuron development	supt5h	IMP	ZFIN:ZDB-GENO-980520-15	Zfish	PMID:10191060
Biological Process	GO:0030097	hemopoiesis	supt5h	IMP	ZFIN:ZDB-MRPHLNO-110210-1	Zfish	PMID:21205096
Biological Process	GO:0032785	negative regulation of DNA-templated transcription, elongation	SUPT5H	IMP		Human	PMID:10075709
Biological Process	GO:0032785	negative regulation of DNA-templated transcription, elongation	SUPT5H	IDA		Human	PMID:9450929
Biological Process	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	supt5h	IMP	ZFIN:ZDB-GENO-090223-1	Zfish	PMID:27520065
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SUPT5H	IMP		Human	PMID:10075709
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	SUPT5H	IDA		Human	PMID:9450929
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	supt5h	IMP	ZFIN:ZDB-GENO-090223-1	Zfish	PMID:18978947
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	supt5h	IMP	ZFIN:ZDB-GENO-090220-3	Zfish	PMID:18978947
Biological Process	GO:0001764	neuron migration	supt5h	IMP	ZFIN:ZDB-GENO-051112-1	Zfish	PMID:16193504
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	SUPT5H	IDA		Human	PMID:9450929
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	supt5h	IMP	ZFIN:ZDB-GENO-090223-1	Zfish	PMID:27520065
Biological Process	GO:1902038	positive regulation of hematopoietic stem cell differentiation	supt5h	IMP	ZFIN:ZDB-GENO-090223-1	Zfish	PMID:27520065
Biological Process	GO:0016239	positive regulation of macroautophagy	SUPT5H	IMP		Human	PMID:22354037
Biological Process	GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	supt5h	IMP	ZFIN:ZDB-GENO-090223-1	Zfish	PMID:27520065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	SUPT5H	IDA		Human	PMID:9450929
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Supt5h	IMP		Rat	PMID:20097260|RGD:9588536
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	supt5h	IMP	ZFIN:ZDB-GENO-090223-1	Zfish	PMID:18978947
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	supt5h	IMP	ZFIN:ZDB-GENO-090220-3	Zfish	PMID:18978947
Biological Process	GO:0060335	positive regulation of type II interferon-mediated signaling pathway	supt5h	IMP	ZFIN:ZDB-GENO-090223-1	Zfish	PMID:27520065
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	supt5h	IMP	ZFIN:ZDB-GENO-090223-1	Zfish	PMID:27520065
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	supt5h	IMP	ZFIN:ZDB-GENO-100513-3	Zfish	PMID:19742326
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	supt5h	IGI	ZFIN:ZDB-GENO-150417-11	Zfish	PMID:19742326
Biological Process	GO:0034243	regulation of transcription elongation by RNA polymerase II	SUPT5H	IDA		Human	PMID:9450929
Biological Process	GO:0006368	transcription elongation by RNA polymerase II	SUPT5H	IMP		Human	PMID:10075709
Biological Process	GO:0006368	transcription elongation by RNA polymerase II	SUPT5H	IDA		Human	PMID:9450929
Biological Process	GO:0006368	transcription elongation by RNA polymerase II	supt5h	IMP	ZFIN:ZDB-GENO-090220-3	Zfish	PMID:18978947

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern