Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SV2A
  • Mouse genes Sv2a
  • Rat genes Sv2a
  • Zfish genes sv2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Sv2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Sv2a	IPI	UniProtKB:O00213	Rat	PMID:24284412|RGD:14697709
Molecular Function	GO:0005515	protein binding	Sv2a	IPI	UniProtKB:P0DPI0	Rat	PMID:24583011|RGD:8554182
Molecular Function	GO:0005515	protein binding	Sv2a	IPI	UniProtKB:P21707	Rat	PMID:8910372|RGD:8553938
Molecular Function	GO:0019901	protein kinase binding	Sv2a	IPI	UniProtKB:Q5S007	Mouse	MGI:MGI:4941068|PMID:21307259
Cellular Component	GO:0005911	cell-cell junction	Sv2a	IDA		Mouse	PMID:12074840
Cellular Component	GO:0030425	dendrite	Sv2a	IDA		Rat	PMID:27265781|RGD:12792961
Cellular Component	GO:0005783	endoplasmic reticulum	SV2A	IDA		Human	GO_REF:0000054
Cellular Component	GO:0098982	GABA-ergic synapse	Sv2a	IDA		Mouse	PMID:19176798
Cellular Component	GO:0098982	GABA-ergic synapse	Sv2a	IMP		Mouse	PMID:19176798
Cellular Component	GO:0098978	glutamatergic synapse	Sv2a	IDA		Mouse	PMID:19176798
Cellular Component	GO:0098978	glutamatergic synapse	Sv2a	IMP		Mouse	PMID:19176798
Cellular Component	GO:0016020	membrane	Sv2a	IDA		Rat	PMID:1519064|RGD:634182
Cellular Component	GO:0031594	neuromuscular junction	Sv2a	IDA		Mouse	PMID:15713258
Cellular Component	GO:0043005	neuron projection	Sv2a	IDA		Mouse	MGI:MGI:5286805|PMID:21664258
Cellular Component	GO:0043025	neuronal cell body	Sv2a	IDA		Rat	PMID:27265781|RGD:12792961
Cellular Component	GO:0048786	presynaptic active zone	Sv2a	IDA		Mouse	MGI:MGI:5286805|PMID:21664258
Cellular Component	GO:0048786	presynaptic active zone	Sv2a	IDA		Mouse	PMID:24035762
Cellular Component	GO:0048786	presynaptic active zone	Sv2a	IDA		Rat	PMID:22875941|RGD:14390063
Cellular Component	GO:0045202	synapse	Sv2a	IDA		Rat	PMID:10712642|RGD:8553882
Cellular Component	GO:0008021	synaptic vesicle	Sv2a	IDA		Mouse	PMID:10624962
Cellular Component	GO:0008021	synaptic vesicle	Sv2a	IDA		Mouse	PMID:12687700
Cellular Component	GO:0008021	synaptic vesicle	Sv2a	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Sv2a	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0030672	synaptic vesicle membrane	Sv2a	IDA		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0030672	synaptic vesicle membrane	Sv2a	IDA		Rat	PMID:1519064|RGD:634182
Cellular Component	GO:0030672	synaptic vesicle membrane	Sv2a	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0043195	terminal bouton	Sv2a	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Sv2a	IDA		Mouse	PMID:10624962
Biological Process	GO:0019227	neuronal action potential propagation	sv2a	IMP	ZFIN:ZDB-GENO-230111-1	Zfish	PMID:35686059
Biological Process	GO:0014052	regulation of gamma-aminobutyric acid secretion	Sv2a	IMP		Rat	PMID:27265781|RGD:12792961
Biological Process	GO:0036269	swimming behavior	sv2a	IMP	ZFIN:ZDB-GENO-230111-1	Zfish	PMID:35686059
Biological Process	GO:0016082	synaptic vesicle priming	Sv2a	IDA		Mouse	PMID:19176798
Biological Process	GO:0016082	synaptic vesicle priming	Sv2a	IMP		Mouse	PMID:19176798

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern