Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SEMG1,SEMG2
  • Mouse genes Svs3a
  • Rat genes Svs3a,Svs3b
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Svs3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002020	protease binding	SEMG2	IPI	UniProtKB:P07288	Human	PMID:8665956
Molecular Function	GO:0005515	protein binding	SEMG1	IPI	UniProtKB:O95925	Human	PMID:15590901
Molecular Function	GO:0005515	protein binding	SEMG1	IPI	UniProtKB:O95925	Human	PMID:19889947
Molecular Function	GO:0005515	protein binding	SEMG1	IPI	UniProtKB:P05154	Human	PMID:8665956
Molecular Function	GO:0005515	protein binding	SEMG1	IPI	UniProtKB:Q02383	Human	PMID:8665956
Molecular Function	GO:0005515	protein binding	SEMG2	IPI	UniProtKB:P04279	Human	PMID:8665956
Molecular Function	GO:0005515	protein binding	SEMG2	IPI	UniProtKB:P05154	Human	PMID:8665956
Molecular Function	GO:0005515	protein binding	SEMG2	IPI	UniProtKB:P05154,UniProtKB:P07288	Human	PMID:8665956
Molecular Function	GO:0008270	zinc ion binding	SEMG1	IMP		Human	PMID:15563730
Molecular Function	GO:0008270	zinc ion binding	SEMG2	IMP		Human	PMID:15563730
Cellular Component	GO:0070062	extracellular exosome	SEMG1	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	SEMG2	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	Svs3a	IDA		Mouse	PMID:11723121
Cellular Component	GO:0005615	extracellular space	SEMG1	IDA		Human	PMID:17567961
Cellular Component	GO:0005615	extracellular space	SEMG1	IDA		Human	PMID:18314226
Cellular Component	GO:0005615	extracellular space	SEMG1	IDA		Human	PMID:18714013
Cellular Component	GO:0005615	extracellular space	SEMG1	IDA		Human	PMID:2912989
Cellular Component	GO:0005615	extracellular space	SEMG1	IDA		Human	PMID:8665951
Cellular Component	GO:0005615	extracellular space	SEMG1	IDA		Human	PMID:8665956
Cellular Component	GO:0005615	extracellular space	SEMG2	IDA		Human	PMID:18714013
Cellular Component	GO:0005615	extracellular space	SEMG2	IDA		Human	PMID:8665951
Cellular Component	GO:0005615	extracellular space	SEMG2	IDA		Human	PMID:8665956
Cellular Component	GO:0005634	nucleus	SEMG1	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	SEMG2	HDA		Human	PMID:21630459
Cellular Component	GO:0032991	protein-containing complex	SEMG1	IDA		Human	PMID:17567961
Biological Process	GO:0019731	antibacterial humoral response	SEMG1	IDA		Human	PMID:18714013
Biological Process	GO:0019731	antibacterial humoral response	SEMG2	IMP		Human	PMID:18714013
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	SEMG1	IDA		Human	PMID:18314226
Biological Process	GO:0050817	coagulation	SEMG1	IDA		Human	PMID:8665956
Biological Process	GO:0050817	coagulation	SEMG2	IDA		Human	PMID:8665956
Biological Process	GO:0031640	killing of cells of another organism	SEMG1	IDA		Human	PMID:18314226
Biological Process	GO:0042628	mating plug formation	Svs3a	IDA		Mouse	PMID:11723121
Biological Process	GO:0090281	negative regulation of calcium ion import	SEMG1	IDA		Human	PMID:22075473
Biological Process	GO:1901318	negative regulation of flagellated sperm motility	SEMG1	IMP		Human	PMID:19889947
Biological Process	GO:1901318	negative regulation of flagellated sperm motility	SEMG1	IDA		Human	PMID:22075473
Biological Process	GO:1900005	positive regulation of serine-type endopeptidase activity	SEMG1	IMP		Human	PMID:15563730
Biological Process	GO:1900005	positive regulation of serine-type endopeptidase activity	SEMG2	IDA		Human	PMID:15563730

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern