Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SWAP70
  • Mouse genes Swap70
  • Rat genes Swap70
  • Zfish genes swap70a,swap70b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Swap70

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Swap70	IDA		Mouse	PMID:9642267
Molecular Function	GO:0045296	cadherin binding	SWAP70	HDA		Human	PMID:25468996
Molecular Function	GO:0003677	DNA binding	Swap70	IDA		Mouse	PMID:9642267
Molecular Function	GO:0005515	protein binding	SWAP70	IPI	UniProtKB:Q8WZA2	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	SWAP70	IPI	UniProtKB:O15062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SWAP70	IPI	UniProtKB:P49591	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SWAP70	IPI	UniProtKB:P53985-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	SWAP70	IPI	UniProtKB:Q8WZA2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Swap70	IPI	UniProtKB:Q61738-6	Mouse	MGI:MGI:3715039|PMID:17403664
Cellular Component	GO:0015629	actin cytoskeleton	SWAP70	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	SWAP70	IDA		Human	PMID:25468996
Cellular Component	GO:0005634	nucleus	Swap70	IDA		Mouse	PMID:9642267
Cellular Component	GO:0005886	plasma membrane	SWAP70	IDA		Human	GO_REF:0000052
Biological Process	GO:0051017	actin filament bundle assembly	Swap70	IDA		Mouse	MGI:MGI:5554982|PMID:23921380
Biological Process	GO:0060026	convergent extension	swap70b	IGI	ZFIN:ZDB-GENE-040426-1246,ZFIN:ZDB-MRPHLNO-140306-3	Zfish	PMID:24177263
Biological Process	GO:0060026	convergent extension	swap70b	IGI	ZFIN:ZDB-MRPHLNO-111207-2,ZFIN:ZDB-MRPHLNO-140306-3	Zfish	PMID:24177263
Biological Process	GO:0060028	convergent extension involved in axis elongation	swap70b	IGI	ZFIN:ZDB-GENE-040426-2150,ZFIN:ZDB-MRPHLNO-140306-3	Zfish	PMID:24177263
Biological Process	GO:0060027	convergent extension involved in gastrulation	swap70b	IMP	ZFIN:ZDB-MRPHLNO-140306-3	Zfish	PMID:24177263
Biological Process	GO:0045190	isotype switching	Swap70	IDA		Mouse	PMID:9642267
Biological Process	GO:0030835	negative regulation of actin filament depolymerization	Swap70	IDA		Mouse	MGI:MGI:5554982|PMID:23921380
Biological Process	GO:0033633	negative regulation of cell-cell adhesion mediated by integrin	Swap70	IMP		Mouse	MGI:MGI:3525048|PMID:15542837
Biological Process	GO:1902309	negative regulation of peptidyl-serine dephosphorylation	Swap70	IMP		Mouse	MGI:MGI:5554982|PMID:23921380
Biological Process	GO:0032233	positive regulation of actin filament bundle assembly	Swap70	IMP		Mouse	MGI:MGI:5554982|PMID:23921380
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Swap70	IMP		Mouse	MGI:MGI:3525048|PMID:15542837
Biological Process	GO:0060754	positive regulation of mast cell chemotaxis	Swap70	IMP		Mouse	MGI:MGI:3525048|PMID:15542837
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	swap70b	IMP	ZFIN:ZDB-MRPHLNO-111129-3	Zfish	PMID:21875669
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	swap70b	IMP	ZFIN:ZDB-MRPHLNO-111129-4	Zfish	PMID:21875669
Biological Process	GO:0008064	regulation of actin polymerization or depolymerization	Swap70	IMP		Mouse	MGI:MGI:3525048|PMID:15542837
Biological Process	GO:0007096	regulation of exit from mitosis	swap70b	IMP	ZFIN:ZDB-MRPHLNO-111129-3	Zfish	PMID:21875669
Biological Process	GO:0007096	regulation of exit from mitosis	swap70b	IMP	ZFIN:ZDB-MRPHLNO-111129-4	Zfish	PMID:21875669
Biological Process	GO:0032880	regulation of protein localization	Swap70	IMP		Mouse	MGI:MGI:3525048|PMID:15542837
Biological Process	GO:0016444	somatic cell DNA recombination	Swap70	IDA		Mouse	PMID:9642267

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern