Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYN2
  • Mouse genes Syn2
  • Rat genes Syn2
  • Zfish genes syn2a,syn2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048306	calcium-dependent protein binding	Syn2	IPI	RGD:3614	Rat	PMID:10567243|RGD:7205635
Molecular Function	GO:0042802	identical protein binding	Syn2	IPI	PR:Q64332	Mouse	PMID:15071120
Molecular Function	GO:0005515	protein binding	SYN2	IPI	UniProtKB:P17600	Human	PMID:23406870
Molecular Function	GO:0005515	protein binding	Syn2	IPI	PR:Q64324	Mouse	PMID:18535671
Molecular Function	GO:0005515	protein binding	Syn2	IPI	UniProtKB:O54960	Rat	PMID:11867766|RGD:8553593
Molecular Function	GO:0005515	protein binding	Syn2	IPI	UniProtKB:P61765	Rat	PMID:17442889|RGD:2312426
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Syn2	IDA		Rat	PMID:2118908|RGD:13702354
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Syn2	IMP		Rat	PMID:2118908|RGD:13702354
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Syn2	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Syn2	IDA		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098978	glutamatergic synapse	Syn2	IDA		Mouse	PMID:25429150
Cellular Component	GO:0098978	glutamatergic synapse	Syn2	IMP		Mouse	PMID:18945891
Cellular Component	GO:0098978	glutamatergic synapse	Syn2	IDA		Mouse	PMID:18945891
Cellular Component	GO:0043209	myelin sheath	Syn2	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005886	plasma membrane	Syn2	IPI	PR:Q64324	Mouse	PMID:18535671
Cellular Component	GO:0005886	plasma membrane	Syn2	IDA		Mouse	PMID:18535671
Cellular Component	GO:0014069	postsynaptic density	Syn2	IDA		Mouse	PMID:17114649
Cellular Component	GO:0098793	presynapse	Syn2	IMP		Mouse	MGI:MGI:74599|PMID:7777057
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Syn2	IDA		Mouse	PMID:7777057
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Syn2	IMP		Mouse	PMID:7777057
Cellular Component	GO:0031201	SNARE complex	Syn2	IDA		Mouse	PMID:18535671
Cellular Component	GO:0045202	synapse	Syn2	IMP		Mouse	MGI:MGI:74599|PMID:7777057
Cellular Component	GO:0045202	synapse	Syn2	IDA		Mouse	PMID:15071120
Cellular Component	GO:0008021	synaptic vesicle	Syn2	IDA		Rat	PMID:11867766|RGD:8553593
Cellular Component	GO:0030672	synaptic vesicle membrane	Syn2	IDA		Mouse	PMID:15071120
Cellular Component	GO:0043195	terminal bouton	Syn2	HDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0017156	calcium-ion regulated exocytosis	Syn2	IMP		Mouse	MGI:MGI:4830800|PMID:20338242
Biological Process	GO:0007269	neurotransmitter secretion	Syn2	IGI	MGI:MGI:98460	Mouse	PMID:7777057
Biological Process	GO:0007269	neurotransmitter secretion	Syn2	IMP	MGI:MGI:1857251	Mouse	PMID:7777057
Biological Process	GO:0097091	synaptic vesicle clustering	Syn2	IMP		Mouse	MGI:MGI:4830800|PMID:20338242
Biological Process	GO:0097091	synaptic vesicle clustering	Syn2	IDA		Mouse	PMID:18945891
Biological Process	GO:0097091	synaptic vesicle clustering	Syn2	IMP		Mouse	PMID:18945891
Biological Process	GO:0099504	synaptic vesicle cycle	Syn2	IMP		Mouse	PMID:7777057
Biological Process	GO:0099504	synaptic vesicle cycle	Syn2	IDA		Mouse	PMID:7777057

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern