Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYNE1
  • Mouse genes Syne1
  • Rat genes
  • Zfish genes syne1a,syne1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syne1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	SYNE1	IDA		Human	PMID:12408964
Molecular Function	GO:0051015	actin filament binding	Syne1	IMP		Mouse	MGI:MGI:5437402|PMID:22518138
Molecular Function	GO:0140444	cytoskeleton-nuclear membrane anchor activity	SYNE1	IDA		Human	PMID:18396275
Molecular Function	GO:0019899	enzyme binding	SYNE1	IPI	UniProtKB:P26196	Human	PMID:24862572
Molecular Function	GO:0019899	enzyme binding	SYNE1	IPI	UniProtKB:Q9NPI6	Human	PMID:24862572
Molecular Function	GO:0019899	enzyme binding	SYNE1	IPI	UniProtKB:Q9UKV8	Human	PMID:24862572
Molecular Function	GO:0042802	identical protein binding	Syne1	IPI	UniProtKB:Q6ZWR6-5	Mouse	MGI:MGI:5437402|PMID:22518138
Molecular Function	GO:0005521	lamin binding	SYNE1	IPI	UniProtKB:P02545	Human	PMID:11801724
Molecular Function	GO:0005515	protein binding	SYNE1	IPI	UniProtKB:Q9NRI5	Human	PMID:12812986
Molecular Function	GO:0005515	protein binding	SYNE1	IPI	UniProtKB:O94901	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SYNE1	IPI	UniProtKB:Q9UH99	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SYNE1	IPI	UniProtKB:Q9UH99	Human	PMID:22632968
Molecular Function	GO:0005515	protein binding	SYNE1	IPI	UniProtKB:P61165	Human	PMID:28716842
Molecular Function	GO:0005515	protein binding	SYNE1	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	Syne1	IPI	UniProtKB:Q6ZMZ3	Mouse	MGI:MGI:5437402|PMID:22518138
Molecular Function	GO:0005515	protein binding	Syne1	IPI	UniProtKB:Q6ZMZ3-1	Mouse	MGI:MGI:5437402|PMID:22518138
Molecular Function	GO:0005515	protein binding	Syne1	IPI	PR:Q61006	Mouse	PMID:10878022
Molecular Function	GO:0005515	protein binding	Syne1	IPI	PR:P10126	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Syne1	IPI	PR:Q9D666	Mouse	PMID:16079285
Molecular Function	GO:0042803	protein homodimerization activity	Syne1	IDA		Mouse	MGI:MGI:5437402|PMID:22518138
Molecular Function	GO:0003723	RNA binding	SYNE1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	SYNE1	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	SYNE1	IDA		Human	PMID:11792814
Cellular Component	GO:0005794	Golgi apparatus	SYNE1	IDA		Human	PMID:12808039
Cellular Component	GO:0034993	meiotic nuclear membrane microtubule tethering complex	SYNE1	IDA		Human	PMID:18396275
Cellular Component	GO:0016020	membrane	SYNE1	IDA		Human	PMID:11792814
Cellular Component	GO:0005635	nuclear envelope	SYNE1	IDA		Human	PMID:11792814
Cellular Component	GO:0005635	nuclear envelope	Syne1	IDA		Mouse	MGI:MGI:5437402|PMID:22518138
Cellular Component	GO:0005635	nuclear envelope	Syne1	IDA		Mouse	PMID:10878022
Cellular Component	GO:0031965	nuclear membrane	SYNE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	SYNE1	IDA		Human	PMID:24862572
Cellular Component	GO:0005654	nucleoplasm	SYNE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	SYNE1	HDA		Human	PMID:21630459
Cellular Component	GO:0000932	P-body	SYNE1	IDA		Human	PMID:24862572
Cellular Component	GO:0045211	postsynaptic membrane	SYNE1	IDA		Human	PMID:10878022
Cellular Component	GO:0030017	sarcomere	SYNE1	IDA		Human	PMID:12408964
Biological Process	GO:0051642	centrosome localization	Syne1	IMP		Mouse	MGI:MGI:4361957|PMID:19596800
Biological Process	GO:0007030	Golgi organization	SYNE1	IDA		Human	PMID:12808039
Biological Process	GO:0007507	heart development	syne1b	IMP	ZFIN:ZDB-MRPHLNO-170927-1	Zfish	PMID:28611029
Biological Process	GO:0007507	heart development	syne1b	IMP	ZFIN:ZDB-MRPHLNO-170927-2	Zfish	PMID:28611029
Biological Process	GO:0042692	muscle cell differentiation	SYNE1	IDA		Human	PMID:11792814
Biological Process	GO:0090292	nuclear matrix anchoring at nuclear membrane	SYNE1	IDA		Human	PMID:11801724
Biological Process	GO:0007097	nuclear migration	Syne1	IMP	MGI:MGI:3700735	Mouse	PMID:17267447
Biological Process	GO:1902017	regulation of cilium assembly	Syne1	IMP		Mouse	MGI:MGI:4361957|PMID:19596800

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern