Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYNE2
  • Mouse genes Syne2
  • Rat genes
  • Zfish genes syne2a,syne2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syne2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Syne2	IDA		Mouse	MGI:MGI:4888085|PMID:20724637
Molecular Function	GO:0140444	cytoskeleton-nuclear membrane anchor activity	SYNE2	IDA		Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:P02545	Human	PMID:15671068
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:P50402	Human	PMID:15671068
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:O94901	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:Q9UH99	Human	PMID:18396275
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:Q9UH99	Human	PMID:22555292
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:Q9UH99	Human	PMID:22632968
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:Q9UKG1	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:Q9Y613	Human	PMID:24880667
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:O00499	Human	PMID:26506308
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:P61165	Human	PMID:28716842
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:Q9UH99	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	SYNE2	IPI	UniProtKB:Q5VW32	Human	PMID:34818527
Molecular Function	GO:0005515	protein binding	Syne2	IPI	UniProtKB:Q9Y613	Mouse	MGI:MGI:5620590|PMID:24880667
Molecular Function	GO:0005515	protein binding	Syne2	IPI	UniProtKB:Q8BJS4-3	Mouse	MGI:MGI:5926036|PMID:26688217
Cellular Component	GO:0005737	cytoplasm	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0005737	cytoplasm	SYNE2	IDA		Human	PMID:12118075
Cellular Component	GO:0070062	extracellular exosome	SYNE2	HDA		Human	PMID:18570454
Cellular Component	GO:0031527	filopodium membrane	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0005925	focal adhesion	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0045111	intermediate filament cytoskeleton	SYNE2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031258	lamellipodium membrane	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0034993	meiotic nuclear membrane microtubule tethering complex	SYNE2	IDA		Human	PMID:18396275
Cellular Component	GO:0005739	mitochondrion	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0030016	myofibril	Syne2	IDA		Mouse	PMID:15671068
Cellular Component	GO:0005635	nuclear envelope	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0005635	nuclear envelope	Syne2	IDA		Mouse	MGI:MGI:5770026|PMID:26506308
Cellular Component	GO:0005635	nuclear envelope	Syne2	IDA		Mouse	PMID:20457914
Cellular Component	GO:0005635	nuclear envelope	Syne2	IDA		Mouse	PMID:15671068
Cellular Component	GO:0031981	nuclear lumen	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0031965	nuclear membrane	SYNE2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	Syne2	IDA		Mouse	PMID:22349700
Cellular Component	GO:0005640	nuclear outer membrane	Syne2	IDA		Mouse	MGI:MGI:4430813|PMID:18396275
Cellular Component	GO:0005634	nucleus	SYNE2	IDA		Human	PMID:12118075
Cellular Component	GO:0016529	sarcoplasmic reticulum	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0030018	Z disc	SYNE2	IDA		Human	PMID:15671068
Cellular Component	GO:0030018	Z disc	Syne2	IDA		Mouse	PMID:15671068
Biological Process	GO:0007015	actin filament organization	syne2b	IMP	ZFIN:ZDB-GENO-220912-1	Zfish	PMID:34222245
Biological Process	GO:0051642	centrosome localization	SYNE2	IMP		Human	PMID:20724637
Biological Process	GO:0051642	centrosome localization	Syne2	IMP		Mouse	MGI:MGI:4412315|PMID:19874786
Biological Process	GO:0051642	centrosome localization	Syne2	IMP		Mouse	MGI:MGI:4888085|PMID:20724637
Biological Process	GO:0051642	centrosome localization	Syne2	IMP		Mouse	MGI:MGI:4361957|PMID:19596800
Biological Process	GO:0090504	epiboly	syne2b	IMP	ZFIN:ZDB-GENO-220912-1	Zfish	PMID:34222245
Biological Process	GO:0007097	nuclear migration	SYNE2	IMP		Human	PMID:20724637
Biological Process	GO:0007097	nuclear migration	syne2a	IMP		Zfish	PMID:17785424
Biological Process	GO:0007097	nuclear migration	syne2a	IMP	ZFIN:ZDB-MRPHLNO-071217-1	Zfish	PMID:17785424
Biological Process	GO:0031022	nuclear migration along microfilament	Syne2	IMP		Mouse	MGI:MGI:4888085|PMID:20724637
Biological Process	GO:0021817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	Syne2	IMP		Mouse	MGI:MGI:4412315|PMID:19874786
Biological Process	GO:0045494	photoreceptor cell maintenance	syne2a	IMP		Zfish	PMID:17785424
Biological Process	GO:0030335	positive regulation of cell migration	Syne2	IMP		Mouse	MGI:MGI:4888085|PMID:20724637
Biological Process	GO:1902017	regulation of cilium assembly	Syne2	IMP		Mouse	MGI:MGI:4361957|PMID:19596800

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern