Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Syt11

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SYT11
- Mouse genes Syt11
- Rat genes Syt11
- Zfish genes syt11a,syt11b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syt11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048487	beta-tubulin binding	Syt11	IPI	UniProtKB:Q6P9T8	Mouse	MGI:MGI:5574516\|PMID:24882364
Molecular Function	GO:0042802	identical protein binding	Syt11	IPI	UniProtKB:Q9R0N3	Mouse	MGI:MGI:5780536\|PMID:22960622
Molecular Function	GO:0005515	protein binding	SYT11	IPI	UniProtKB:Q92624	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	SYT11	IPI	UniProtKB:Q92624	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	SYT11	IPI	UniProtKB:O43765	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	SYT11	IPI	UniProtKB:Q9NQ11	Human	PMID:22645275
Molecular Function	GO:0005515	protein binding	SYT11	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	SYT11	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT11	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	SYT11	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Syt11	IPI	UniProtKB:P33173	Mouse	MGI:MGI:6296681\|PMID:30808661
Molecular Function	GO:0005515	protein binding	Syt11	IPI	UniProtKB:M0RCY2\|UniProtKB:P13084\|UniProtKB:P13383\|UniProtKB:P47727\|UniProtKB:P49242\|UniProtKB:P62271\|UniProtKB:P62909\|UniProtKB:P63326\|UniProtKB:Q63081\|UniProtKB:Q63945\|UniProtKB:Q66X93\|UniProtKB:Q80WE1\|UniProtKB:Q9EST6\|UniProtKB:Q9QZ81	Mouse	MGI:MGI:5574516\|PMID:24882364
Molecular Function	GO:0005515	protein binding	Syt11	IPI	UniProtKB:Q7KZF4	Mouse	MGI:MGI:5574516\|PMID:24882364
Molecular Function	GO:0005515	protein binding	Syt11	IPI	UniProtKB:Q9JI51	Mouse	MGI:MGI:5574516\|PMID:24882364
Molecular Function	GO:0005515	protein binding	Syt11	IPI	UniProtKB:F1LTE0	Rat	PMID:30021165\|RGD:14995321
Molecular Function	GO:0000149	SNARE binding	Syt11	IPI	UniProtKB:Q9JI51	Mouse	MGI:MGI:5574516\|PMID:24882364
Molecular Function	GO:0000149	SNARE binding	Syt11	IPI	UniProtKB:P58200	Mouse	MGI:MGI:5574516\|PMID:24882364
Molecular Function	GO:0031369	translation initiation factor binding	Syt11	IPI	UniProtKB:Q1JU68\|UniProtKB:Q4G061	Mouse	MGI:MGI:5574516\|PMID:24882364
Molecular Function	GO:0031625	ubiquitin protein ligase binding	SYT11	IPI	UniProtKB:O60260	Human	PMID:12925569
Cellular Component	GO:0030424	axon	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0030424	axon	Syt11	IDA		Rat	PMID:26589353\|RGD:11079192
Cellular Component	GO:0044297	cell body	Syt11	IDA		Rat	PMID:26589353\|RGD:11079192
Cellular Component	GO:0005737	cytoplasm	Syt11	IDA		Mouse	MGI:MGI:5468041\|PMID:23303671
Cellular Component	GO:0030425	dendrite	Syt11	IDA		Mouse	MGI:MGI:6296681\|PMID:30808661
Cellular Component	GO:0043197	dendritic spine	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0098691	dopaminergic synapse	Syt11	IDA		Mouse	PMID:29311685
Cellular Component	GO:0098691	dopaminergic synapse	Syt11	IMP		Mouse	PMID:29311685
Cellular Component	GO:0032009	early phagosome	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Cellular Component	GO:0032009	early phagosome	Syt11	IDA		Mouse	MGI:MGI:5468041\|PMID:23303671
Cellular Component	GO:0060076	excitatory synapse	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0060077	inhibitory synapse	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0005764	lysosome	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Cellular Component	GO:0005764	lysosome	Syt11	IDA		Mouse	MGI:MGI:5468041\|PMID:23303671
Cellular Component	GO:0005764	lysosome	Syt11	IDA		Mouse	MGI:MGI:5788615\|PMID:26450452
Cellular Component	GO:0043005	neuron projection	SYT11	IDA		Human	PMID:12925569
Cellular Component	GO:0043005	neuron projection	Syt11	IDA		Rat	PMID:12925569\|RGD:11541113
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Syt11	IDA		Rat	PMID:12925569\|RGD:11541113
Cellular Component	GO:0001891	phagocytic cup	Syt11	IDA		Mouse	MGI:MGI:5468041\|PMID:23303671
Cellular Component	GO:0045335	phagocytic vesicle	Syt11	IDA		Mouse	MGI:MGI:5780534\|PMID:25063865
Cellular Component	GO:0005886	plasma membrane	Syt11	IDA		Mouse	PMID:11171101
Cellular Component	GO:0098794	postsynapse	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0014069	postsynaptic density	Syt11	IDA		Mouse	MGI:MGI:6296681\|PMID:30808661
Cellular Component	GO:0014069	postsynaptic density	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0098793	presynapse	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0048787	presynaptic active zone membrane	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0055037	recycling endosome	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Cellular Component	GO:0055037	recycling endosome	Syt11	IDA		Mouse	MGI:MGI:5468041\|PMID:23303671
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0008021	synaptic vesicle	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0030672	synaptic vesicle membrane	Syt11	IDA		Rat	PMID:22960622\|RGD:11079184
Cellular Component	GO:0043195	terminal bouton	Syt11	IDA		Rat	PMID:12925569\|RGD:11541113
Cellular Component	GO:0005802	trans-Golgi network	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Cellular Component	GO:0031982	vesicle	Syt11	IDA		Mouse	MGI:MGI:6296681\|PMID:30808661
Cellular Component	GO:0031982	vesicle	Syt11	IDA		Rat	PMID:26589353\|RGD:11079192
Biological Process	GO:0006914	autophagy	SYT11	IMP		Human	PMID:27278822
Biological Process	GO:0006914	autophagy	Syt11	IMP		Mouse	MGI:MGI:5881999\|PMID:27278822
Biological Process	GO:1990927	calcium ion regulated lysosome exocytosis	Syt11	IMP		Mouse	MGI:MGI:5788615\|PMID:26450452
Biological Process	GO:0051650	establishment of vesicle localization	Syt11	IMP		Mouse	MGI:MGI:6296681\|PMID:30808661
Biological Process	GO:0007612	learning	Syt11	IMP		Mouse	MGI:MGI:6296681\|PMID:30808661
Biological Process	GO:0007613	memory	Syt11	IMP		Mouse	MGI:MGI:6296681\|PMID:30808661
Biological Process	GO:1905444	negative regulation of clathrin coat assembly	Syt11	IMP		Rat	PMID:26589353\|RGD:11079192
Biological Process	GO:1900186	negative regulation of clathrin-dependent endocytosis	Syt11	IMP		Rat	PMID:26589353\|RGD:11079192
Biological Process	GO:0001818	negative regulation of cytokine production	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Biological Process	GO:0033602	negative regulation of dopamine secretion	Syt11	IDA		Mouse	MGI:MGI:6114813\|PMID:29311685
Biological Process	GO:0033602	negative regulation of dopamine secretion	Syt11	IDA		Rat	PMID:29311685\|RGD:14929208
Biological Process	GO:0045806	negative regulation of endocytosis	Syt11	IDA		Mouse	MGI:MGI:6114813\|PMID:29311685
Biological Process	GO:0045806	negative regulation of endocytosis	Syt11	IDA		Rat	PMID:29311685\|RGD:14929208
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Syt11	IMP		Mouse	MGI:MGI:5468041\|PMID:23303671
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Syt11	IMP		Mouse	MGI:MGI:5780534\|PMID:25063865
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Biological Process	GO:1905154	negative regulation of membrane invagination	Syt11	IMP		Rat	PMID:26589353\|RGD:11079192
Biological Process	GO:1903979	negative regulation of microglial cell activation	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Biological Process	GO:0050765	negative regulation of phagocytosis	Syt11	IMP		Mouse	MGI:MGI:5468041\|PMID:23303671
Biological Process	GO:0050765	negative regulation of phagocytosis	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Biological Process	GO:1900243	negative regulation of synaptic vesicle endocytosis	Syt11	IMP		Rat	PMID:26589353\|RGD:11079192
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Syt11	IMP		Mouse	MGI:MGI:5780534\|PMID:25063865
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Syt11	IMP		Mouse	MGI:MGI:5468041\|PMID:23303671
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Syt11	IDA		Mouse	MGI:MGI:5913303\|PMID:28686317
Biological Process	GO:0001778	plasma membrane repair	Syt11	IMP		Mouse	MGI:MGI:5788615\|PMID:26450452
Biological Process	GO:1905171	positive regulation of protein localization to phagocytic vesicle	Syt11	IMP		Mouse	MGI:MGI:5468041\|PMID:23303671
Biological Process	GO:1900424	regulation of defense response to bacterium	Syt11	IMP		Mouse	MGI:MGI:5468041\|PMID:23303671
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Syt11	IDA		Mouse	PMID:29311685
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Syt11	IMP		Mouse	PMID:29311685
Biological Process	GO:0009611	response to wounding	Syt11	IMP		Mouse	MGI:MGI:5788615\|PMID:26450452

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.