Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYT5
  • Mouse genes Syt5
  • Rat genes Syt5
  • Zfish genes syt5a,syt5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syt5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	SYT5	IDA		Human	PMID:27793683
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt5	IDA		Mouse	MGI:MGI:5795832|PMID:8626542
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt5	IDA		Rat	PMID:7791877|RGD:61762
Molecular Function	GO:0030276	clathrin binding	Syt5	IDA		Rat	PMID:7791877|RGD:61762
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Syt5	IDA		Mouse	MGI:MGI:5780544|PMID:12860971
Molecular Function	GO:0001786	phosphatidylserine binding	Syt5	IDA		Mouse	MGI:MGI:5780544|PMID:12860971
Molecular Function	GO:0046982	protein heterodimerization activity	Syt5	IPI	UniProtKB:Q9R0N8-1	Mouse	MGI:MGI:5142391|PMID:10531344
Molecular Function	GO:0000149	SNARE binding	Syt5	IDA		Mouse	MGI:MGI:5780544|PMID:12860971
Molecular Function	GO:0019905	syntaxin binding	Syt5	IDA		Rat	PMID:7791877|RGD:61762
Cellular Component	GO:0031045	dense core granule	Syt5	IDA		Mouse	PMID:16407767
Cellular Component	GO:0031045	dense core granule	Syt5	IDA		Mouse	PMID:14622145
Cellular Component	GO:0043005	neuron projection	Syt5	IDA		Mouse	PMID:15197251
Cellular Component	GO:0043025	neuronal cell body	Syt5	IDA		Mouse	PMID:15197251
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	Syt5	IDA		Mouse	PMID:12006594
Cellular Component	GO:0099012	neuronal dense core vesicle membrane	Syt5	IEP		Mouse	PMID:12006594
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Syt5	IDA		Mouse	PMID:15197251
Cellular Component	GO:1990769	proximal neuron projection	Syt5	IDA		Mouse	MGI:MGI:3047044|PMID:15197251
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	Syt5	IMP		Mouse	MGI:MGI:5780544|PMID:12860971

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern