Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Syt7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes SYT7
- Mouse genes Syt7
- Rat genes Syt7
- Zfish genes syt7a,syt7b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syt7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Syt7	IMP		Rat	PMID:11395007\|RGD:634203
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt7	IDA		Mouse	MGI:MGI:3690533\|PMID:16982801
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt7	IDA		Rat	PMID:11395007\|RGD:634203
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Syt7	IDA		Rat	PMID:7791877\|RGD:61762
Molecular Function	GO:0005516	calmodulin binding	Syt7	IDA		Mouse	MGI:MGI:5560382\|PMID:24569478
Molecular Function	GO:0030276	clathrin binding	Syt7	IDA		Rat	PMID:7791877\|RGD:61762
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Syt7	IDA		Mouse	MGI:MGI:5645834\|PMID:25860611
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Syt7	IDA		Mouse	MGI:MGI:5780544\|PMID:12860971
Molecular Function	GO:0001786	phosphatidylserine binding	Syt7	IDA		Mouse	MGI:MGI:5780544\|PMID:12860971
Molecular Function	GO:0005515	protein binding	SYT7	IPI	UniProtKB:Q8IUQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Syt7	IPI	UniProtKB:P41731	Mouse	MGI:MGI:4849340\|PMID:21041449
Molecular Function	GO:0005515	protein binding	Syt7	IPI	UniProtKB:O35526	Rat	PMID:26437117\|RGD:11060704
Molecular Function	GO:0000149	SNARE binding	Syt7	IDA		Mouse	MGI:MGI:5780544\|PMID:12860971
Molecular Function	GO:0019905	syntaxin binding	Syt7	IDA		Rat	PMID:7791877\|RGD:61762
Cellular Component	GO:0043679	axon terminus	Syt7	IDA		Mouse	MGI:MGI:5795818\|PMID:21576241
Cellular Component	GO:0030425	dendrite	Syt7	IDA		Mouse	MGI:MGI:5795818\|PMID:21576241
Cellular Component	GO:0031045	dense core granule	Syt7	IDA		Rat	PMID:20016973\|RGD:7241272
Cellular Component	GO:0031045	dense core granule	Syt7	IDA		Rat	PMID:21551071\|RGD:7205660
Cellular Component	GO:0032009	early phagosome	Syt7	IDA		Mouse	MGI:MGI:3690533\|PMID:16982801
Cellular Component	GO:0070062	extracellular exosome	SYT7	HDA		Human	PMID:23533145
Cellular Component	GO:0098982	GABA-ergic synapse	Syt7	IMP		Mouse	PMID:24267651
Cellular Component	GO:0098982	GABA-ergic synapse	Syt7	IDA		Mouse	PMID:24267651
Cellular Component	GO:0098978	glutamatergic synapse	Syt7	IMP		Mouse	PMID:24267651
Cellular Component	GO:0098978	glutamatergic synapse	Syt7	IDA		Mouse	PMID:24267651
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Syt7	IDA		Rat	PMID:11395007\|RGD:634203
Cellular Component	GO:0005764	lysosome	Syt7	IDA		Mouse	MGI:MGI:5645834\|PMID:25860611
Cellular Component	GO:0005764	lysosome	Syt7	IDA		Mouse	MGI:MGI:4849340\|PMID:21041449
Cellular Component	GO:0005764	lysosome	Syt7	IDA		Mouse	PMID:12925704
Cellular Component	GO:0005764	lysosome	Syt7	IDA		Rat	PMID:10725327\|RGD:2311145
Cellular Component	GO:0005764	lysosome	Syt7	IDA		Rat	PMID:11511344\|RGD:11041027
Cellular Component	GO:0043025	neuronal cell body	Syt7	IDA		Mouse	MGI:MGI:5795818\|PMID:21576241
Cellular Component	GO:0005777	peroxisome	Syt7	IDA		Mouse	MGI:MGI:5645834\|PMID:25860611
Cellular Component	GO:0005886	plasma membrane	Syt7	IDA		Rat	PMID:17709608\|RGD:2311143
Cellular Component	GO:0098793	presynapse	syt7b	IMP	ZFIN:ZDB-MRPHLNO-100823-1	Zfish	PMID:20643933\|ZFIN:ZDB-PUB-100726-11
Cellular Component	GO:0042734	presynaptic membrane	Syt7	IDA		Mouse	MGI:MGI:1935012\|PMID:11395007
Cellular Component	GO:0042734	presynaptic membrane	Syt7	IDA		Rat	PMID:11395007\|RGD:634203
Cellular Component	GO:0045202	synapse	syt7b	IMP	ZFIN:ZDB-MRPHLNO-100823-1	Zfish	PMID:20643933\|ZFIN:ZDB-PUB-100726-11
Cellular Component	GO:0008021	synaptic vesicle	Syt7	IMP		Mouse	MGI:MGI:5560382\|PMID:24569478
Cellular Component	GO:0043195	terminal bouton	Syt7	HDA		Rat	PMID:24876496\|RGD:10047219
Biological Process	GO:0071912	asynchronous neurotransmitter secretion	syt7b	IMP	ZFIN:ZDB-MRPHLNO-100823-1	Zfish	PMID:20643933
Biological Process	GO:1990927	calcium ion regulated lysosome exocytosis	Syt7	IMP		Mouse	MGI:MGI:3690533\|PMID:16982801
Biological Process	GO:1990927	calcium ion regulated lysosome exocytosis	Syt7	IMP		Mouse	MGI:MGI:3798323\|PMID:18539119
Biological Process	GO:1990927	calcium ion regulated lysosome exocytosis	Syt7	IDA		Rat	PMID:10725327\|RGD:2311145
Biological Process	GO:1990927	calcium ion regulated lysosome exocytosis	Syt7	IDA		Rat	PMID:11511344\|RGD:11041027
Biological Process	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	Syt7	IMP		Mouse	MGI:MGI:5707519\|PMID:26738595
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Syt7	IMP		Mouse	PMID:24267651
Biological Process	GO:0099502	calcium-dependent activation of synaptic vesicle fusion	Syt7	IDA		Mouse	PMID:24267651
Biological Process	GO:0017156	calcium-ion regulated exocytosis	Syt7	IDA		Rat	PMID:11395007\|RGD:634203
Biological Process	GO:0006909	phagocytosis	Syt7	IMP		Mouse	MGI:MGI:4849340\|PMID:21041449
Biological Process	GO:0090385	phagosome-lysosome fusion	Syt7	IMP		Mouse	MGI:MGI:3690533\|PMID:16982801
Biological Process	GO:0001778	plasma membrane repair	Syt7	IDA		Mouse	PMID:12925704
Biological Process	GO:0001778	plasma membrane repair	Syt7	IDA		Rat	PMID:11511344\|RGD:11041027
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Syt7	IDA		Rat	PMID:21551071\|RGD:7205660
Biological Process	GO:0046850	regulation of bone remodeling	Syt7	IMP		Mouse	MGI:MGI:3798323\|PMID:18539119
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	Syt7	IMP		Mouse	MGI:MGI:5780544\|PMID:12860971
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	Syt7	IMP		Rat	PMID:10725327\|RGD:2311145
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	Syt7	IMP		Rat	PMID:20016973\|RGD:7241272
Biological Process	GO:0014059	regulation of dopamine secretion	Syt7	IMP		Mouse	MGI:MGI:5795818\|PMID:21576241
Biological Process	GO:0070092	regulation of glucagon secretion	Syt7	IMP		Mouse	MGI:MGI:4848029\|PMID:19171650
Biological Process	GO:0050796	regulation of insulin secretion	Syt7	IMP		Mouse	MGI:MGI:3773625\|PMID:18308938
Biological Process	GO:0050796	regulation of insulin secretion	Syt7	IMP		Rat	PMID:17709608\|RGD:2311143
Biological Process	GO:0050764	regulation of phagocytosis	Syt7	IMP		Mouse	MGI:MGI:3690533\|PMID:16982801
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Syt7	IDA		Rat	PMID:14532108\|RGD:155230716
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Syt7	IMP		Rat	PMID:14532108\|RGD:155230716
Biological Process	GO:1990926	short-term synaptic potentiation	Syt7	IDA		Mouse	MGI:MGI:5707519\|PMID:26738595
Biological Process	GO:1990926	short-term synaptic potentiation	Syt7	IMP		Mouse	MGI:MGI:5560382\|PMID:24569478
Biological Process	GO:0036465	synaptic vesicle recycling	Syt7	IMP		Mouse	MGI:MGI:5560382\|PMID:24569478
Biological Process	GO:0090119	vesicle-mediated cholesterol transport	Syt7	IDA		Mouse	MGI:MGI:5645834\|PMID:25860611

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.