Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYVN1
  • Mouse genes Syvn1
  • Rat genes Syvn1
  • Zfish genes syvn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Syvn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	SYVN1	IPI	UniProtKB:P55072	Human	PMID:16186510
Molecular Function	GO:0051117	ATPase binding	SYVN1	IPI	UniProtKB:P55072	Human	PMID:22590560
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:P04637	Human	PMID:17170702
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q13438	Human	PMID:18264092
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q96DZ1	Human	PMID:18264092
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:O75460	Human	PMID:18369366
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:P11021	Human	PMID:18502753
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q96DZ1-1	Human	PMID:18502753
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9UBV2	Human	PMID:18502753
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:O75460	Human	PMID:19135427
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9Y385	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:O75477	Human	PMID:21343306
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:O94905	Human	PMID:21343306
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:O00124	Human	PMID:21949850
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:O75477	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:O94905	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9UBU6	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9UBV2	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9Y385	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:P54252	Human	PMID:24068323
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9UBV2	Human	PMID:26471130
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:O75460-1	Human	PMID:26551274
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q13438|UniProtKB:Q15011|UniProtKB:Q9UBU6|UniProtKB:Q9UBV2|UniProtKB:Q9Y385	Human	PMID:28827405
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9UBU6	Human	PMID:28827405
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9UBV2	Human	PMID:28827405
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9Y385	Human	PMID:28827405
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9UBV2	Human	PMID:31477895
Molecular Function	GO:0005515	protein binding	SYVN1	IPI	UniProtKB:Q9Y4E8	Human	PMID:31477895
Molecular Function	GO:0005515	protein binding	Syvn1	IPI	UniProtKB:Q61985:PRO_0000076448	Mouse	MGI:MGI:5299399|PMID:21911472
Molecular Function	GO:0005515	protein binding	Syvn1	IPI	UniProtKB:P13372|UniProtKB:P20764	Mouse	MGI:MGI:6220623|PMID:29907570
Molecular Function	GO:0005515	protein binding	Syvn1	IPI	UniProtKB:Q9Z2G6	Mouse	MGI:MGI:5606246|PMID:25066055
Molecular Function	GO:0005515	protein binding	Syvn1	IPI	UniProtKB:P57716	Mouse	MGI:MGI:5508580|PMID:19725872
Molecular Function	GO:0051087	protein-folding chaperone binding	SYVN1	IPI	UniProtKB:P46379	Human	PMID:21636303
Molecular Function	GO:0061630	ubiquitin protein ligase activity	SYVN1	IDA		Human	PMID:12459480
Molecular Function	GO:0061630	ubiquitin protein ligase activity	SYVN1	IDA		Human	PMID:14593114
Molecular Function	GO:0061630	ubiquitin protein ligase activity	SYVN1	IDA		Human	PMID:17059562
Molecular Function	GO:0061630	ubiquitin protein ligase activity	SYVN1	IDA		Human	PMID:19103148
Molecular Function	GO:0061630	ubiquitin protein ligase activity	SYVN1	IMP		Human	PMID:21245296
Molecular Function	GO:0061630	ubiquitin protein ligase activity	SYVN1	IMP		Human	PMID:28842558
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Syvn1	IMP		Mouse	MGI:MGI:6220623|PMID:29907570
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Syvn1	IDA		Mouse	MGI:MGI:5299399|PMID:21911472
Molecular Function	GO:1990381	ubiquitin-specific protease binding	SYVN1	IPI	UniProtKB:Q9UHP3	Human	PMID:22590560
Molecular Function	GO:1990381	ubiquitin-specific protease binding	SYVN1	IPI	UniProtKB:Q5VVQ6	Human	PMID:24068323
Molecular Function	GO:0051082	unfolded protein binding	SYVN1	IPI	UniProtKB:O15354	Human	PMID:17059562
Cellular Component	GO:0036513	Derlin-1 retrotranslocation complex	SYVN1	IDA		Human	PMID:21454652
Cellular Component	GO:0005783	endoplasmic reticulum	SYVN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	SYVN1	IDA		Human	PMID:12459480
Cellular Component	GO:0005783	endoplasmic reticulum	SYVN1	IDA		Human	PMID:14593114
Cellular Component	GO:0005783	endoplasmic reticulum	SYVN1	IDA		Human	PMID:17059562
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	SYVN1	IDA		Human	PMID:23233672
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	SYVN1	IDA		Human	PMID:24478453
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	Syvn1	IDA		Mouse	MGI:MGI:6467680|PMID:17707796
Cellular Component	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex	SYVN1	IMP		Human	PMID:26471130
Cellular Component	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex	SYVN1	IDA		Human	PMID:28827405
Cellular Component	GO:0016020	membrane	SYVN1	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	SYVN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005790	smooth endoplasmic reticulum	SYVN1	IDA		Human	PMID:16186510
Biological Process	GO:0036503	ERAD pathway	SYVN1	IDA		Human	PMID:22590560
Biological Process	GO:0036503	ERAD pathway	SYVN1	IMP		Human	PMID:26471130
Biological Process	GO:0036503	ERAD pathway	Syvn1	IDA		Mouse	MGI:MGI:5645202|PMID:21454652
Biological Process	GO:0002327	immature B cell differentiation	Syvn1	IMP		Mouse	MGI:MGI:6220623|PMID:29907570
Biological Process	GO:0001701	in utero embryonic development	Syvn1	IMP	MGI:MGI:2679656	Mouse	PMID:15611074
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Syvn1	IMP	MGI:MGI:2679656	Mouse	PMID:15611074
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	SYVN1	IDA		Human	PMID:12459480
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	SYVN1	IDA		Human	PMID:17059562
Biological Process	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Syvn1	IMP	MGI:MGI:2679656	Mouse	PMID:15611074
Biological Process	GO:0030163	protein catabolic process	Syvn1	IMP		Mouse	MGI:MGI:5009360|PMID:20160352
Biological Process	GO:0070936	protein K48-linked ubiquitination	SYVN1	IDA		Human	PMID:14593114
Biological Process	GO:0050821	protein stabilization	SYVN1	IMP		Human	PMID:21454652
Biological Process	GO:0050821	protein stabilization	Syvn1	IDA		Mouse	MGI:MGI:5645202|PMID:21454652
Biological Process	GO:0016567	protein ubiquitination	SYVN1	IDA		Human	PMID:12459480
Biological Process	GO:0016567	protein ubiquitination	SYVN1	IDA		Human	PMID:22590560
Biological Process	GO:0030970	retrograde protein transport, ER to cytosol	SYVN1	IMP		Human	PMID:25660456
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	SYVN1	IMP		Human	PMID:21245296
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	SYVN1	IDA		Human	PMID:12459480
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	SYVN1	IDA		Human	PMID:14593114
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	SYVN1	IDA		Human	PMID:17059562
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	SYVN1	IMP		Human	PMID:22607976
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	SYVN1	IMP		Human	PMID:28827405
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	SYVN1	IDA		Human	PMID:14593114
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	SYVN1	IDA		Human	PMID:17059562
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Syvn1	IDA		Mouse	MGI:MGI:5299399|PMID:21911472

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern