Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SZT2
  • Mouse genes Szt2
  • Rat genes Szt2
  • Zfish genes szt2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Szt2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	SZT2	IPI	UniProtKB:Q12980	Human	PMID:28199315
Molecular Function	GO:0005515	protein binding	SZT2	IPI	UniProtKB:Q96S15	Human	PMID:28199315
Cellular Component	GO:0140007	KICSTOR complex	SZT2	IDA		Human	PMID:28199306
Cellular Component	GO:0005765	lysosomal membrane	SZT2	IDA		Human	PMID:28199315
Cellular Component	GO:0005777	peroxisome	Szt2	IDA		Mouse	MGI:MGI:5545991|PMID:20045724
Biological Process	GO:0034198	cellular response to amino acid starvation	SZT2	IMP		Human	PMID:28199306
Biological Process	GO:0034198	cellular response to amino acid starvation	SZT2	IMP		Human	PMID:28199315
Biological Process	GO:0042149	cellular response to glucose starvation	SZT2	IMP		Human	PMID:28199306
Biological Process	GO:0042149	cellular response to glucose starvation	SZT2	IMP		Human	PMID:28199315
Biological Process	GO:0007417	central nervous system development	Szt2	IMP	MGI:MGI:4353996	Mouse	PMID:19624305
Biological Process	GO:0021540	corpus callosum morphogenesis	SZT2	IMP		Human	PMID:23932106
Biological Process	GO:1904262	negative regulation of TORC1 signaling	SZT2	IMP		Human	PMID:28199306
Biological Process	GO:1904262	negative regulation of TORC1 signaling	SZT2	IMP		Human	PMID:28199315
Biological Process	GO:1904262	negative regulation of TORC1 signaling	Szt2	IMP		Mouse	MGI:MGI:5883356|PMID:28199306
Biological Process	GO:1904262	negative regulation of TORC1 signaling	Szt2	IMP		Mouse	MGI:MGI:5897504|PMID:28199315
Biological Process	GO:0043473	pigmentation	Szt2	IMP	MGI:MGI:4353996	Mouse	PMID:19624305
Biological Process	GO:0009791	post-embryonic development	Szt2	IMP	MGI:MGI:4353996	Mouse	PMID:19624305
Biological Process	GO:0061462	protein localization to lysosome	SZT2	IMP		Human	PMID:28199306
Biological Process	GO:1901668	regulation of superoxide dismutase activity	Szt2	IMP		Mouse	MGI:MGI:5545991|PMID:20045724
Biological Process	GO:0031667	response to nutrient levels	Szt2	IMP		Mouse	MGI:MGI:5897504|PMID:28199315

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern