Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAB2
  • Mouse genes Tab2
  • Rat genes Tab2
  • Zfish genes tab2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tab2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	TAB2	IDA		Human	PMID:15327770
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	TAB2	IDA		Human	PMID:19935683
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	TAB2	IDA		Human	PMID:22158122
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318	Human	PMID:11460167
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9Y4K3	Human	PMID:11518704
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318-2	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q15750	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318	Human	PMID:16845370
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q15750	Human	PMID:16845370
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318	Human	PMID:17158449
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q62073	Human	PMID:17158449
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9BYM8	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318-2	Human	PMID:19026643
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q62073	Human	PMID:19675569
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9Y4K3	Human	PMID:19675569
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9C035	Human	PMID:21512573
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q15750	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:P15407	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q05516	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q15750	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9Y4K3	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318	Human	PMID:22081109
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q14457	Human	PMID:22081109
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:B7UI22	Human	PMID:22158122
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318	Human	PMID:22158122
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9UKE5	Human	PMID:22904686
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q15750	Human	PMID:25260751
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318	Human	PMID:27426733
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q15750	Human	PMID:27880917
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:P06753	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:P15407	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:P52747	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:P78386	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q8N1B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9NTW7-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9UQM7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:Q9Y6C2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB2	IPI	UniProtKB:O43318	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Tab2	IPI	UniProtKB:Q62073	Mouse	MGI:MGI:3708399|PMID:17158449
Molecular Function	GO:0005515	protein binding	Tab2	IPI	UniProtKB:Q62073	Mouse	MGI:MGI:5553034|PMID:24270572
Molecular Function	GO:0005515	protein binding	Tab2	IPI	UniProtKB:Q62073	Mouse	MGI:MGI:5512957|PMID:19026643
Molecular Function	GO:0005515	protein binding	Tab2	IPI	RGD:1307579	Rat	PMID:18299187|RGD:5507831
Molecular Function	GO:0005515	protein binding	Tab2	IPI	UniProtKB:A1L1I3	Rat	PMID:18299187|RGD:5507831
Molecular Function	GO:0008270	zinc ion binding	TAB2	IDA		Human	PMID:22158122
Biological Process	GO:0043009	chordate embryonic development	tab2	IMP	ZFIN:ZDB-MRPHLNO-101227-1	Zfish	PMID:20493459
Biological Process	GO:0060027	convergent extension involved in gastrulation	tab2	IMP	ZFIN:ZDB-MRPHLNO-101227-1	Zfish	PMID:20493459
Biological Process	GO:0007507	heart development	TAB2	IMP		Human	PMID:20493459
Biological Process	GO:0007507	heart development	tab2	IMP		Zfish	PMID:20493459|ZFIN:ZDB-PUB-100525-18
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TAB2	IEP		Human	PMID:12761501
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TAB2	IDA		Human	PMID:15327770
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TAB2	IDA		Human	PMID:22158122
Biological Process	GO:0045860	positive regulation of protein kinase activity	TAB2	IDA		Human	PMID:11460167
Biological Process	GO:0032496	response to lipopolysaccharide	TAB2	IDA		Human	PMID:19193853

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern