Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAB3
  • Mouse genes Tab3
  • Rat genes Tab3
  • Zfish genes tab3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tab3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	TAB3	IDA		Human	PMID:15327770
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	TAB3	IDA		Human	PMID:22158122
Molecular Function	GO:0060090	molecular adaptor activity	TAB3	IDA		Human	PMID:15327770
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:Q62073	Human	PMID:17158449
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:Q9BYM8	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:Q9C035	Human	PMID:21512573
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:O43318	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:O43318	Human	PMID:22081109
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:Q14457	Human	PMID:22081109
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:P57077-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:Q13526	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:Q8IYX8-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:P57077-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAB3	IPI	UniProtKB:O43318	Human	PMID:32707033
Molecular Function	GO:0008270	zinc ion binding	TAB3	IDA		Human	PMID:22158122
Cellular Component	GO:0005783	endoplasmic reticulum	TAB3	IDA		Human	PMID:15327770
Cellular Component	GO:0070062	extracellular exosome	TAB3	HDA		Human	PMID:18570454
Biological Process	GO:0038061	NIK/NF-kappaB signaling	TAB3	IDA		Human	PMID:15327770
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TAB3	IDA		Human	PMID:15327770
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TAB3	IDA		Human	PMID:22158122
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TAB3	IMP		Human	PMID:23487264

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern