Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAC4
  • Mouse genes Tac4
  • Rat genes Tac4
  • Zfish genes si:ch211-131k2.2,tac4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tac4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0048018	receptor ligand activity	Tac4	IDA		Mouse	MGI:MGI:5924533|PMID:12716968
Molecular Function	GO:0005102	signaling receptor binding	Tac4	IDA		Mouse	PMID:11062498
Molecular Function	GO:0031837	substance K receptor binding	Tac4	IPI	UniProtKB:P21452	Mouse	MGI:MGI:5924533|PMID:12716968
Molecular Function	GO:0031835	substance P receptor binding	Tac4	IPI	UniProtKB:P25103	Mouse	MGI:MGI:5924533|PMID:12716968
Cellular Component	GO:0005615	extracellular space	TAC4	IDA		Human	PMID:17437961
Cellular Component	GO:0005615	extracellular space	Tac4	IDA		Rat	PMID:17655832|RGD:14695074
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	Tac4	IDA		Rat	PMID:17655832|RGD:14695074
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Tac4	IDA		Mouse	MGI:MGI:5924533|PMID:12716968
Biological Process	GO:1902093	positive regulation of flagellated sperm motility	TAC4	IDA		Human	PMID:17437961
Biological Process	GO:0046878	positive regulation of saliva secretion	Tac4	IDA		Mouse	PMID:11062498
Biological Process	GO:1904058	positive regulation of sensory perception of pain	Tac4	IDA		Rat	PMID:17655832|RGD:14695074
Biological Process	GO:0007217	tachykinin receptor signaling pathway	Tac4	IDA		Mouse	MGI:MGI:5924533|PMID:12716968
Biological Process	GO:0007217	tachykinin receptor signaling pathway	Tac4	IDA		Mouse	PMID:11062498

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern