Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TACSTD2
  • Mouse genes Tacstd2
  • Rat genes Tacstd2
  • Zfish genes epcam
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tacstd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TACSTD2	IPI	UniProtKB:P27958:PRO_0000037576	Human	PMID:15607035
Molecular Function	GO:0005515	protein binding	TACSTD2	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TACSTD2	IPI	UniProtKB:Q5TA81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TACSTD2	IPI	UniProtKB:Q701N4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TACSTD2	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Cellular Component	GO:0009925	basal plasma membrane	Tacstd2	IDA		Mouse	MGI:MGI:5315060|PMID:22194864
Cellular Component	GO:0016323	basolateral plasma membrane	epcam	IDA		Zfish	PMID:19609345
Cellular Component	GO:0070062	extracellular exosome	TACSTD2	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	Tacstd2	IDA		Mouse	PMID:23070813
Cellular Component	GO:0016328	lateral plasma membrane	Tacstd2	IDA		Mouse	MGI:MGI:5315060|PMID:22194864
Cellular Component	GO:0016020	membrane	Tacstd2	IDA		Mouse	PMID:23070813
Cellular Component	GO:0005634	nucleus	Tacstd2	IDA		Mouse	PMID:23070813
Cellular Component	GO:0048471	perinuclear region of cytoplasm	epcam	IDA		Zfish	PMID:16552761
Cellular Component	GO:0005886	plasma membrane	Tacstd2	IDA		Mouse	PMID:9462726
Cellular Component	GO:0005886	plasma membrane	epcam	IDA		Zfish	PMID:23484855
Cellular Component	GO:0005886	plasma membrane	epcam	IDA		Zfish	PMID:16552761
Biological Process	GO:0098609	cell-cell adhesion	epcam	IGI	ZFIN:ZDB-MRPHLNO-050421-1	Zfish	PMID:19609345
Biological Process	GO:0044782	cilium organization	epcam	IMP	ZFIN:ZDB-GENO-221020-4	Zfish	PMID:33693707
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	epcam	IGI	ZFIN:ZDB-MRPHLNO-050421-1	Zfish	PMID:19609345
Biological Process	GO:0001889	liver development	epcam	IGI	ZFIN:ZDB-MRPHLNO-100308-1	Zfish	PMID:23484855
Biological Process	GO:0001889	liver development	epcam	IGI	ZFIN:ZDB-MRPHLNO-060824-3	Zfish	PMID:23484855
Biological Process	GO:0001889	liver development	epcam	IMP	ZFIN:ZDB-GENO-140424-7	Zfish	PMID:23484855
Biological Process	GO:0001889	liver development	epcam	IGI	ZFIN:ZDB-GENO-111223-13,ZFIN:ZDB-MRPHLNO-130430-1	Zfish	PMID:23484855
Biological Process	GO:0002009	morphogenesis of an epithelium	epcam	IMP	ZFIN:ZDB-GENO-110729-1	Zfish	PMID:19609345
Biological Process	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis	Tacstd2	IDA		Mouse	MGI:MGI:5315060|PMID:22194864
Biological Process	GO:2000146	negative regulation of cell motility	Tacstd2	IDA		Mouse	MGI:MGI:5315060|PMID:22194864
Biological Process	GO:0010633	negative regulation of epithelial cell migration	Tacstd2	IDA		Mouse	MGI:MGI:5315060|PMID:22194864
Biological Process	GO:1900028	negative regulation of ruffle assembly	Tacstd2	IDA		Mouse	MGI:MGI:5315060|PMID:22194864
Biological Process	GO:0051497	negative regulation of stress fiber assembly	Tacstd2	IDA		Mouse	MGI:MGI:5315060|PMID:22194864
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	Tacstd2	IDA		Mouse	MGI:MGI:5315060|PMID:22194864
Biological Process	GO:0032475	otolith formation	epcam	IMP	ZFIN:ZDB-GENO-221020-4	Zfish	PMID:33693707
Biological Process	GO:2000738	positive regulation of stem cell differentiation	Tacstd2	IDA		Mouse	PMID:23070813
Biological Process	GO:0048920	posterior lateral line neuromast primordium migration	epcam	IGI	ZFIN:ZDB-MRPHLNO-070507-5,ZFIN:ZDB-MRPHLNO-080310-1	Zfish	PMID:29945870
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Tacstd2	IEP		Mouse	MGI:MGI:5315060|PMID:22194864
Biological Process	GO:0060675	ureteric bud morphogenesis	Tacstd2	IEP		Mouse	MGI:MGI:5315060|PMID:22194864

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern