Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAF1,TAF1L
  • Mouse genes Taf1
  • Rat genes
  • Zfish genes taf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Taf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Taf1	IDA		Mouse	PMID:18722179
Molecular Function	GO:0061628	H3K27me3 modified histone binding	TAF1	IPI	UniProtKB:Q15545	Human	PMID:24927529
Molecular Function	GO:0004402	histone acetyltransferase activity	TAF1	IDA		Human	PMID:8980232
Molecular Function	GO:0004402	histone acetyltransferase activity	Taf1	IDA		Mouse	MGI:MGI:3847877|PMID:11592977
Molecular Function	GO:0016301	kinase activity	TAF1	IDA		Human	PMID:18548200
Molecular Function	GO:0070577	lysine-acetylated histone binding	TAF1	IDA		Human	PMID:17996705
Molecular Function	GO:0070577	lysine-acetylated histone binding	TAF1L	IDA		Human	PMID:22464331
Molecular Function	GO:0016922	nuclear receptor binding	TAF1	IPI	UniProtKB:P10275	Human	PMID:20181722
Molecular Function	GO:0002039	p53 binding	TAF1	IPI	UniProtKB:P04637	Human	PMID:15053879
Molecular Function	GO:1990841	promoter-specific chromatin binding	Taf1	IDA		Mouse	PMID:22323595
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P17480	Human	PMID:12498690
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:Q96IU4	Human	PMID:14672934
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P20226	Human	PMID:17884155
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P20226	Human	PMID:18391197
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P68400	Human	PMID:18548200
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:Q00987	Human	PMID:18548200
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P15207	Human	PMID:20181722
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:Q00987	Human	PMID:20181722
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P03255	Human	PMID:7565781
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P35269	Human	PMID:7590250
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P49848-1	Human	PMID:7667268
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P20226	Human	PMID:7680771
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:O00268	Human	PMID:7729427
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P20226	Human	PMID:7729427
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:Q15545	Human	PMID:7824954
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P20226	Human	PMID:9603525
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P20226	Human	PMID:9674425
Molecular Function	GO:0005515	protein binding	TAF1	IPI	UniProtKB:P06400	Human	PMID:9858607
Molecular Function	GO:0005515	protein binding	Taf1	IPI	UniProtKB:Q15545|UniProtKB:Q9R1C0	Mouse	MGI:MGI:3847877|PMID:11592977
Molecular Function	GO:0005515	protein binding	Taf1	IPI	UniProtKB:Q15545	Mouse	MGI:MGI:6092622|PMID:16407123
Molecular Function	GO:0005515	protein binding	Taf1	IPI	PR:Q9D3R9	Mouse	PMID:12665565
Molecular Function	GO:0046982	protein heterodimerization activity	TAF1	IPI	UniProtKB:Q15545	Human	PMID:25412659
Molecular Function	GO:0004672	protein kinase activity	TAF1	IDA		Human	PMID:24289924
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAF1	EXP		Human	PMID:15053879
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAF1	IDA		Human	PMID:15053879
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAF1	IDA		Human	PMID:8625415
Molecular Function	GO:0001181	RNA polymerase I general transcription initiation factor activity	TAF1	IDA		Human	PMID:12498690
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	TAF1	IMP		Human	PMID:25412659
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	TAF1	IDA		Human	PMID:17996705
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	TAF1	IGI	UniProtKB:Q15545	Human	PMID:25412659
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	TAF1	IPI	UniProtKB:P35269	Human	PMID:8625415
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	TAF1	IPI	UniProtKB:P04637	Human	PMID:24289924
Molecular Function	GO:0017025	TBP-class protein binding	TAF1	IPI	UniProtKB:P53360	Human	PMID:9660973
Molecular Function	GO:0017025	TBP-class protein binding	TAF1L	IPI	UniProtKB:P20226	Human	PMID:12217962
Molecular Function	GO:0140416	transcription regulator inhibitor activity	TAF1	IDA		Human	PMID:24289924
Molecular Function	GO:0061631	ubiquitin conjugating enzyme activity	TAF1	IDA		Human	PMID:20181722
Cellular Component	GO:0000785	chromatin	TAF1	IDA		Human	PMID:20181722
Cellular Component	GO:0000785	chromatin	TAF1	IDA		Human	PMID:24289924
Cellular Component	GO:0071339	MLL1 complex	TAF1	IDA		Human	PMID:15960975
Cellular Component	GO:0005730	nucleolus	TAF1	IDA		Human	PMID:12498690
Cellular Component	GO:0005654	nucleoplasm	TAF1	IDA		Human	PMID:12498690
Cellular Component	GO:0005654	nucleoplasm	TAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TAF1	IDA		Human	PMID:12498690
Cellular Component	GO:0005634	nucleus	TAF1	EXP		Human	PMID:23332750
Cellular Component	GO:0005634	nucleus	TAF1	IDA		Human	PMID:25593309
Cellular Component	GO:0045120	pronucleus	Taf1	IDA		Mouse	PMID:16822332
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF1	IPI		Human	PMID:23332750
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF1	IDA		Human	PMID:14580349
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF1	IDA		Human	PMID:24927529
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF1	IDA		Human	PMID:25412659
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF1	IDA		Human	PMID:27007846
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF1	IDA		Human	PMID:29111974
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF1	IDA		Human	PMID:8625415
Cellular Component	GO:0005667	transcription regulator complex	TAF1	IPI	UniProtKB:Q15545	Human	PMID:25412659
Biological Process	GO:0071318	cellular response to ATP	TAF1	IDA		Human	PMID:24289924
Biological Process	GO:0034644	cellular response to UV	TAF1	IDA		Human	PMID:24289924
Biological Process	GO:0048589	developmental growth	taf1	IMP	ZFIN:ZDB-GENO-191213-4	Zfish	PMID:31341187
Biological Process	GO:0048589	developmental growth	taf1	IMP	ZFIN:ZDB-GENO-191213-3	Zfish	PMID:31341187
Biological Process	GO:0006974	DNA damage response	TAF1	IDA		Human	PMID:24289924
Biological Process	GO:0007140	male meiotic nuclear division	TAF1L	IEP		Human	PMID:12217962
Biological Process	GO:0030901	midbrain development	TAF1	IGI	UniProtKB:Q1LYC2	Human	PMID:26637982
Biological Process	GO:0030901	midbrain development	taf1	IMP	ZFIN:ZDB-MRPHLNO-160316-3	Zfish	PMID:26637982
Biological Process	GO:0030901	midbrain development	taf1	IMP	ZFIN:ZDB-CRISPR-160226-1	Zfish	PMID:26637982
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	TAF1	IDA		Human	PMID:17884155
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	TAF1	IDA		Human	PMID:24289924
Biological Process	GO:0010629	negative regulation of gene expression	TAF1	IMP		Human	PMID:17237821
Biological Process	GO:1905524	negative regulation of protein autoubiquitination	TAF1	IDA		Human	PMID:17237821
Biological Process	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	TAF1	IDA		Human	PMID:24289924
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TAF1	IMP		Human	PMID:24289924
Biological Process	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	TAF1	IMP		Human	PMID:17237821
Biological Process	GO:0018105	peptidyl-serine phosphorylation	TAF1	IDA		Human	PMID:8625415
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	TAF1	IDA		Human	PMID:15053879
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	TAF1	IDA		Human	PMID:24289924
Biological Process	GO:2000825	positive regulation of androgen receptor activity	TAF1	IDA		Human	PMID:20181722
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TAF1L	IDA		Human	PMID:12217962
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	TAF1	IDA		Human	PMID:15053879
Biological Process	GO:0032092	positive regulation of protein binding	TAF1	IDA		Human	PMID:17237821
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	TAF1	IDA		Human	PMID:17884155
Biological Process	GO:0046777	protein autophosphorylation	TAF1	IDA		Human	PMID:20181722
Biological Process	GO:0046777	protein autophosphorylation	TAF1	IDA		Human	PMID:24289924
Biological Process	GO:0046777	protein autophosphorylation	TAF1	IDA		Human	PMID:8625415
Biological Process	GO:0006468	protein phosphorylation	TAF1	IDA		Human	PMID:15053879
Biological Process	GO:0006468	protein phosphorylation	TAF1	IDA		Human	PMID:18548200
Biological Process	GO:0000209	protein polyubiquitination	TAF1	IDA		Human	PMID:20181722
Biological Process	GO:0050821	protein stabilization	TAF1	IDA		Human	PMID:17237821
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	TAF1L	IDA		Human	PMID:12217962
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	TAF1	IPI		Human	PMID:27007846
Biological Process	GO:0006366	transcription by RNA polymerase II	TAF1	IGI	UniProtKB:Q60544	Human	PMID:9660973
Biological Process	GO:0036369	transcription factor catabolic process	TAF1	IDA		Human	PMID:20181722
Biological Process	GO:0006361	transcription initiation at RNA polymerase I promoter	TAF1	IGI	UniProtKB:P17480,UniProtKB:Q15572	Human	PMID:12498690
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	TAF1	IDA		Human	PMID:17996705
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	TAF1	IGI	UniProtKB:Q60544	Human	PMID:25412659
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	TAF1	IDA		Human	PMID:20181722

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern