Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAF4
  • Mouse genes Taf4
  • Rat genes Taf4
  • Zfish genes taf4a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Taf4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017162	aryl hydrocarbon receptor binding	TAF4	IPI	UniProtKB:P35869	Human	PMID:15641800
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	TAF4	IDA		Human	PMID:15601843
Molecular Function	GO:0003677	DNA binding	Taf4	IDA		Mouse	PMID:18722179
Molecular Function	GO:0005515	protein binding	TAF4	IPI	UniProtKB:P17544	Human	PMID:15735663
Molecular Function	GO:0005515	protein binding	TAF4	IPI	UniProtKB:O43889	Human	PMID:17483474
Molecular Function	GO:0005515	protein binding	TAF4	IPI	UniProtKB:Q9NS37	Human	PMID:17483474
Molecular Function	GO:0005515	protein binding	TAF4	IPI	UniProtKB:Q16514-1	Human	PMID:23292512
Molecular Function	GO:0005515	protein binding	TAF4	IPI	UniProtKB:P21675	Human	PMID:7729427
Molecular Function	GO:0005515	protein binding	TAF4	IPI	UniProtKB:Q6P1X5	Human	PMID:9418870
Molecular Function	GO:0005515	protein binding	Taf4	IPI	PR:P29037	Mouse	PMID:12665565
Molecular Function	GO:0005515	protein binding	Taf4	IPI	RGD:1561940	Rat	PMID:15911349|RGD:9681720
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	TAF4	IDA		Human	PMID:9603525
Cellular Component	GO:0000785	chromatin	TAF4	IDA		Human	PMID:24289924
Cellular Component	GO:0005829	cytosol	TAF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001673	male germ cell nucleus	Taf4	IDA		Mouse	PMID:12665565
Cellular Component	GO:0071339	MLL1 complex	TAF4	IDA		Human	PMID:15960975
Cellular Component	GO:0005654	nucleoplasm	TAF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TAF4	EXP		Human	PMID:23332750
Cellular Component	GO:0005634	nucleus	Taf4	IDA		Mouse	PMID:22323595
Cellular Component	GO:0005634	nucleus	Taf4	IDA		Mouse	PMID:18722179
Cellular Component	GO:0005634	nucleus	Taf4	IDA		Rat	PMID:15911349|RGD:9681720
Cellular Component	GO:0032991	protein-containing complex	TAF4	IMP		Human	PMID:15641800
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF4	IPI		Human	PMID:23332750
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF4	IDA		Human	PMID:14580349
Cellular Component	GO:0005669	transcription factor TFIID complex	TAF4	IDA		Human	PMID:29111974
Cellular Component	GO:0033276	transcription factor TFTC complex	TAF4	IDA		Human	PMID:10373431
Cellular Component	GO:0033276	transcription factor TFTC complex	TAF4	IDA		Human	PMID:9603525
Biological Process	GO:0006351	DNA-templated transcription	Taf4	IDA		Mouse	PMID:11570813
Biological Process	GO:0006352	DNA-templated transcription initiation	TAF4	IDA		Human	PMID:9603525
Biological Process	GO:0043966	histone H3 acetylation	TAF4	IDA		Human	PMID:10373431
Biological Process	GO:0035521	monoubiquitinated histone deubiquitination	TAF4	IDA		Human	PMID:18206972
Biological Process	GO:0035522	monoubiquitinated histone H2A deubiquitination	TAF4	IDA		Human	PMID:18206972
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	TAF4	IDA		Human	PMID:17884155
Biological Process	GO:0001541	ovarian follicle development	Taf4	IMP	MGI:MGI:2152347	Mouse	PMID:11557891
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	TAF4	IDA		Human	PMID:17884155
Biological Process	GO:0006468	protein phosphorylation	TAF4	IDA		Human	PMID:15053879
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	TAF4	IDA		Human	PMID:9603525
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	TAF4	IPI		Human	PMID:27007846
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	TAF4	IDA		Human	PMID:12771217
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	TAF4	IDA		Human	PMID:9603525

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern