Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAFAZZIN
  • Mouse genes Tafazzin
  • Rat genes
  • Zfish genes tafazzin
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tafazzin

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity	TAFAZZIN	IDA		Human	PMID:12930833
Cellular Component	GO:0005743	mitochondrial inner membrane	TAFAZZIN	IDA		Human	PMID:26908608
Cellular Component	GO:0005741	mitochondrial outer membrane	TAFAZZIN	IDA		Human	PMID:26908608
Cellular Component	GO:0005739	mitochondrion	TAFAZZIN	IDA		Human	PMID:15304507
Biological Process	GO:0060048	cardiac muscle contraction	TAFAZZIN	IMP		Human	PMID:17043667
Biological Process	GO:0048738	cardiac muscle tissue development	TAFAZZIN	IMP		Human	PMID:17043667
Biological Process	GO:0032049	cardiolipin biosynthetic process	TAFAZZIN	IMP		Human	PMID:11118295
Biological Process	GO:0032049	cardiolipin biosynthetic process	TAFAZZIN	IMP		Human	PMID:16873891
Biological Process	GO:0032049	cardiolipin biosynthetic process	TAFAZZIN	IMP		Human	PMID:17043667
Biological Process	GO:0032049	cardiolipin biosynthetic process	TAFAZZIN	IMP		Human	PMID:19164547
Biological Process	GO:0032048	cardiolipin metabolic process	TAFAZZIN	IDA		Human	PMID:26908608
Biological Process	GO:0032048	cardiolipin metabolic process	TAFAZZIN	IMP		Human	PMID:33096711
Biological Process	GO:0032048	cardiolipin metabolic process	Tafazzin	IMP		Mouse	MGI:MGI:5819036|PMID:26114544
Biological Process	GO:0032048	cardiolipin metabolic process	Tafazzin	IMP		Mouse	MGI:MGI:4868510|PMID:21068380
Biological Process	GO:0042407	cristae formation	TAFAZZIN	IMP		Human	PMID:17043667
Biological Process	GO:0007507	heart development	TAFAZZIN	IMP		Human	PMID:17043667
Biological Process	GO:0007507	heart development	tafazzin	IMP	ZFIN:ZDB-MRPHLNO-060918-5	Zfish	PMID:16794186
Biological Process	GO:0007507	heart development	tafazzin	IMP	ZFIN:ZDB-MRPHLNO-060918-3	Zfish	PMID:16794186
Biological Process	GO:0007507	heart development	tafazzin	IMP	ZFIN:ZDB-MRPHLNO-060918-4	Zfish	PMID:16794186
Biological Process	GO:0001947	heart looping	tafazzin	IMP	ZFIN:ZDB-MRPHLNO-060918-3	Zfish	PMID:16794186
Biological Process	GO:0003007	heart morphogenesis	Tafazzin	IMP		Mouse	MGI:MGI:4868510|PMID:21068380
Biological Process	GO:0030097	hemopoiesis	TAFAZZIN	IMP		Human	PMID:17043667
Biological Process	GO:0042775	mitochondrial ATP synthesis coupled electron transport	TAFAZZIN	IDA		Human	PMID:15304507
Biological Process	GO:0032981	mitochondrial respiratory chain complex I assembly	TAFAZZIN	IMP		Human	PMID:16857210
Biological Process	GO:0007005	mitochondrion organization	Tafazzin	IMP		Mouse	MGI:MGI:4868510|PMID:21068380
Biological Process	GO:0000423	mitophagy	TAFAZZIN	IMP		Human	PMID:33096711
Biological Process	GO:0000423	mitophagy	Tafazzin	IMP		Mouse	MGI:MGI:6450300|PMID:25919711
Biological Process	GO:0006936	muscle contraction	TAFAZZIN	IMP		Human	PMID:17043667
Biological Process	GO:0045823	positive regulation of heart contraction	tafazzin	IMP	ZFIN:ZDB-MRPHLNO-060918-3	Zfish	PMID:16794186
Biological Process	GO:0007519	skeletal muscle tissue development	TAFAZZIN	IMP		Human	PMID:17043667
Biological Process	GO:0048137	spermatocyte division	Tafazzin	IMP		Mouse	MGI:MGI:5819036|PMID:26114544

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern