Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAOK2
  • Mouse genes Taok2
  • Rat genes Taok2
  • Zfish genes taok2a,taok2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Taok2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Taok2	IDA		Rat	PMID:15458637|RGD:7240553
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Taok2	IDA		Rat	PMID:10497253|RGD:634175
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	TAOK2	IPI	UniProtKB:P46734	Human	PMID:11279118
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	TAOK2	IPI	UniProtKB:P52564	Human	PMID:11279118
Molecular Function	GO:0038191	neuropilin binding	TAOK2	IPI	UniProtKB:P97333	Human	PMID:22683681
Molecular Function	GO:0038191	neuropilin binding	Taok2	IPI	UniProtKB:P97333	Mouse	MGI:MGI:5462161|PMID:22683681
Molecular Function	GO:0005515	protein binding	TAOK2	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAOK2	IPI	UniProtKB:Q9UPY8	Human	PMID:32296183
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAOK2	IDA		Human	PMID:10660600
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TAOK2	IDA		Human	PMID:11279118
Cellular Component	GO:0015629	actin cytoskeleton	Taok2	IDA		Mouse	MGI:MGI:5462161|PMID:22683681
Cellular Component	GO:0030424	axon	Taok2	IDA		Mouse	MGI:MGI:5462161|PMID:22683681
Cellular Component	GO:0044295	axonal growth cone	Taok2	IDA		Mouse	MGI:MGI:5462161|PMID:22683681
Cellular Component	GO:0031410	cytoplasmic vesicle	TAOK2	IDA		Human	PMID:10660600
Cellular Component	GO:0005829	cytosol	TAOK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0044294	dendritic growth cone	Taok2	IDA		Mouse	MGI:MGI:5462161|PMID:22683681
Cellular Component	GO:0098978	glutamatergic synapse	Taok2	IDA		Rat	PMID:17988630|RGD:13702360
Cellular Component	GO:0098978	glutamatergic synapse	Taok2	IMP		Rat	PMID:17988630|RGD:13702360
Cellular Component	GO:0098978	glutamatergic synapse	Taok2	IDA		Rat	PMID:28065648|RGD:155230793
Cellular Component	GO:0098978	glutamatergic synapse	Taok2	IMP		Rat	PMID:28065648|RGD:155230793
Cellular Component	GO:0043005	neuron projection	Taok2	IDA		Mouse	MGI:MGI:5462161|PMID:22683681
Cellular Component	GO:0005730	nucleolus	TAOK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TAOK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098794	postsynapse	Taok2	IDA		Rat	PMID:28065648|RGD:155230793
Cellular Component	GO:0043235	receptor complex	TAOK2	IDA		Human	PMID:23382219
Biological Process	GO:0030036	actin cytoskeleton organization	TAOK2	IDA		Human	PMID:10660600
Biological Process	GO:0007409	axonogenesis	TAOK2	IGI	UniProtKB:Q6ZQ29	Human	PMID:22683681
Biological Process	GO:0007409	axonogenesis	Taok2	IMP		Mouse	MGI:MGI:5462161|PMID:22683681
Biological Process	GO:0007409	axonogenesis	Taok2	IGI	UniProtKB:Q9UL54	Mouse	MGI:MGI:5462161|PMID:22683681
Biological Process	GO:0150020	basal dendrite arborization	Taok2	IDA		Mouse	MGI:MGI:5462161|PMID:22683681
Biological Process	GO:0150020	basal dendrite arborization	Taok2	IGI	UniProtKB:O08665,UniProtKB:P97333	Rat	PMID:22683681|RGD:13461760
Biological Process	GO:0150019	basal dendrite morphogenesis	Taok2	IMP	UniProtKB:Q9UL54	Mouse	MGI:MGI:5462161|PMID:22683681
Biological Process	GO:0150019	basal dendrite morphogenesis	Taok2	IMP	UniProtKB:Q9UL54	Rat	PMID:22683681|RGD:13461760
Biological Process	GO:0007420	brain development	taok2a	IMP	ZFIN:ZDB-MRPHLNO-121210-8	Zfish	PMID:22566537
Biological Process	GO:1904888	cranial skeletal system development	taok2b	IMP	ZFIN:ZDB-CRISPR-200506-7	Zfish	PMID:31553903
Biological Process	GO:1904888	cranial skeletal system development	taok2a	IMP	ZFIN:ZDB-CRISPR-200506-6	Zfish	PMID:31553903
Biological Process	GO:0006974	DNA damage response	TAOK2	IDA		Human	PMID:17396146
Biological Process	GO:0048041	focal adhesion assembly	TAOK2	IDA		Human	PMID:10660600
Biological Process	GO:0000165	MAPK cascade	Taok2	IDA		Rat	PMID:10497253|RGD:634175
Biological Process	GO:0030901	midbrain development	taok2b	IMP	ZFIN:ZDB-MRPHLNO-121207-23	Zfish	PMID:22566537
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	TAOK2	IMP		Human	PMID:17396146
Biological Process	GO:0046330	positive regulation of JNK cascade	TAOK2	IDA		Human	PMID:10660600
Biological Process	GO:0046330	positive regulation of JNK cascade	Taok2	IMP		Mouse	MGI:MGI:5462161|PMID:22683681
Biological Process	GO:0043410	positive regulation of MAPK cascade	TAOK2	IDA		Human	PMID:10660600
Biological Process	GO:0032874	positive regulation of stress-activated MAPK cascade	TAOK2	IMP		Human	PMID:17396146
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Taok2	IDA		Mouse	MGI:MGI:5462161|PMID:22683681
Biological Process	GO:0008360	regulation of cell shape	TAOK2	IDA		Human	PMID:10660600
Biological Process	GO:0099175	regulation of postsynapse organization	Taok2	IDA		Rat	PMID:28065648|RGD:155230793
Biological Process	GO:0099175	regulation of postsynapse organization	Taok2	IMP		Rat	PMID:28065648|RGD:155230793
Biological Process	GO:0099179	regulation of synaptic membrane adhesion	Taok2	IDA		Rat	PMID:17988630|RGD:13702360
Biological Process	GO:0099179	regulation of synaptic membrane adhesion	Taok2	IEP		Rat	PMID:17988630|RGD:13702360
Biological Process	GO:0099179	regulation of synaptic membrane adhesion	Taok2	IMP		Rat	PMID:17988630|RGD:13702360
Biological Process	GO:0051403	stress-activated MAPK cascade	TAOK2	IDA		Human	PMID:11279118

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern