Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TAP1
  • Mouse genes Tap1
  • Rat genes Tap1
  • Zfish genes tap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015433	ABC-type peptide antigen transporter activity	TAP1	IDA		Human	PMID:11133832
Molecular Function	GO:0015433	ABC-type peptide antigen transporter activity	TAP1	IDA		Human	PMID:25377891
Molecular Function	GO:0015433	ABC-type peptide antigen transporter activity	TAP1	IMP		Human	PMID:25656091
Molecular Function	GO:0015433	ABC-type peptide antigen transporter activity	Tap1	EXP		Mouse	MGI:MGI:5767072|PMID:12645939
Molecular Function	GO:0015433	ABC-type peptide antigen transporter activity	Tap1	EXP		Mouse	MGI:MGI:5767079|PMID:8342042
Molecular Function	GO:0043531	ADP binding	TAP1	IDA		Human	PMID:11532960
Molecular Function	GO:0043531	ADP binding	Tap1	IDA		Rat	PMID:15611256|RGD:2312376
Molecular Function	GO:0005524	ATP binding	TAP1	IDA		Human	PMID:11133832
Molecular Function	GO:0005524	ATP binding	TAP1	IMP		Human	PMID:15793001
Molecular Function	GO:0005524	ATP binding	TAP1	IDA		Human	PMID:7673167
Molecular Function	GO:0005524	ATP binding	Tap1	IDA		Rat	PMID:12047747|RGD:5147838
Molecular Function	GO:0005524	ATP binding	Tap1	IDA		Rat	PMID:15611256|RGD:2312376
Molecular Function	GO:0016887	ATP hydrolysis activity	Tap1	IDA		Rat	PMID:17018292|RGD:2312374
Molecular Function	GO:0042288	MHC class I protein binding	Tap1	IPI	PR:P14427	Mouse	PMID:14735325
Molecular Function	GO:0042288	MHC class I protein binding	Tap1	IDA		Rat	PMID:12047747|RGD:5147838
Molecular Function	GO:0023029	MHC class Ib protein binding	TAP1	IPI	UniProtKB:P30511	Human	PMID:10605026
Molecular Function	GO:0000166	nucleotide binding	Tap1	IDA		Rat	PMID:14622282|RGD:1300480
Molecular Function	GO:0042605	peptide antigen binding	TAP1	IDA		Human	PMID:7500034
Molecular Function	GO:0042605	peptide antigen binding	Tap1	IDA		Rat	PMID:10508608|RGD:1601415
Molecular Function	GO:1904680	peptide transmembrane transporter activity	TAP1	IGI	UniProtKB:Q03519	Human	PMID:7673167
Molecular Function	GO:1904680	peptide transmembrane transporter activity	TAP1	IMP		Human	PMID:17418234
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:O15533	Human	PMID:12213826
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q77CE4	Human	PMID:15793001
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:16828748
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:O15533	Human	PMID:17055437
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:P07237	Human	PMID:17055437
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:P27797	Human	PMID:17055437
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:P30101	Human	PMID:17055437
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:17055437
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:O15533	Human	PMID:18802093
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:O15533,UniProtKB:P61769,UniProtKB:Q03519,UniProtKB:Q77CE4,UniProtKB:Q96DN0	Human	PMID:18802093
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:18802093
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q77CE4	Human	PMID:18802093
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q13769	Human	PMID:19165146
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:O15533	Human	PMID:19201886
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:P0C739	Human	PMID:19201886
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:19201886
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:19297616
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:P0C739	Human	PMID:22810586
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:26789246
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:P30101	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:P57678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:P60508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q5TA81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q6ZMZ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TAP1	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Tap1	IPI	UniProtKB:P36372	Rat	PMID:18802093|RGD:10448954
Molecular Function	GO:0005515	protein binding	Tap1	IPI	UniProtKB:Q77CE4,UniProtKB:Q99JC6	Rat	PMID:18802093|RGD:10448954
Molecular Function	GO:0005515	protein binding	Tap1	IPI	UniProtKB:Q99JC6	Rat	PMID:18802093|RGD:10448954
Molecular Function	GO:0042803	protein homodimerization activity	Tap1	IPI	UniProtKB:P36370	Rat	PMID:12047747|RGD:5147838
Molecular Function	GO:0044877	protein-containing complex binding	Tap1	IDA		Rat	PMID:11595746|RGD:2312377
Molecular Function	GO:0044877	protein-containing complex binding	Tap1	IDA		Rat	PMID:12047747|RGD:5147838
Molecular Function	GO:0046978	TAP1 binding	Tap1	IPI	UniProtKB:P36370	Rat	PMID:12047747|RGD:5147838
Molecular Function	GO:0046979	TAP2 binding	TAP1	IPI	UniProtKB:P36371	Human	PMID:11133832
Molecular Function	GO:0046979	TAP2 binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:1538751
Molecular Function	GO:0046979	TAP2 binding	TAP1	IPI	UniProtKB:Q03519	Human	PMID:15518576
Molecular Function	GO:0046979	TAP2 binding	Tap1	IPI	RGD:3818	Rat	PMID:12047747|RGD:5147838
Molecular Function	GO:0046979	TAP2 binding	Tap1	IPI	UniProtKB:P36372	Rat	PMID:12047747|RGD:5147838
Molecular Function	GO:0046980	tapasin binding	Tap1	IDA		Rat	PMID:12047747|RGD:5147838
Molecular Function	GO:0046980	tapasin binding	Tap1	IPI	UniProtKB:O15533	Rat	PMID:12047747|RGD:5147838
Cellular Component	GO:0034451	centriolar satellite	TAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	TAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAP1	IDA		Human	PMID:11133832
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAP1	IDA		Human	PMID:15577206
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAP1	IDA		Human	PMID:22638925
Cellular Component	GO:0005789	endoplasmic reticulum membrane	TAP1	IDA		Human	PMID:7673167
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Tap1	IDA		Rat	PMID:16624807|RGD:2312375
Cellular Component	GO:0016020	membrane	TAP1	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	TAP1	IDA		Human	PMID:8955196
Cellular Component	GO:0042824	MHC class I peptide loading complex	TAP1	IDA		Human	PMID:17947644
Cellular Component	GO:0042824	MHC class I peptide loading complex	Tap1	IDA		Rat	PMID:17947644|RGD:13792542
Cellular Component	GO:0005739	mitochondrion	Tap1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0042825	TAP complex	TAP1	IDA		Human	PMID:11133832
Cellular Component	GO:0042825	TAP complex	TAP1	IDA		Human	PMID:15518576
Cellular Component	GO:0042825	TAP complex	TAP1	IDA		Human	PMID:17947644
Cellular Component	GO:0042825	TAP complex	Tap1	IDA		Rat	PMID:11595746|RGD:2312377
Cellular Component	GO:0042825	TAP complex	Tap1	IDA		Rat	PMID:14622282|RGD:1300480
Cellular Component	GO:0042825	TAP complex	Tap1	IDA		Rat	PMID:17947644|RGD:13792542
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	TAP1	IDA		Human	PMID:11133832
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	TAP1	IMP		Human	PMID:11133832
Biological Process	GO:0046967	cytosol to endoplasmic reticulum transport	TAP1	IMP		Human	PMID:7538543
Biological Process	GO:0006952	defense response	Tap1	IMP	MGI:MGI:1857253	Mouse	PMID:1473153
Biological Process	GO:0015833	peptide transport	TAP1	IMP		Human	PMID:11133832
Biological Process	GO:0015833	peptide transport	TAP1	IMP		Human	PMID:17418234
Biological Process	GO:0015833	peptide transport	Tap1	IMP		Rat	PMID:15611256|RGD:2312376
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity	Tap1	IMP		Rat	PMID:8120379|RGD:2312378

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern