Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBC1D10C
  • Mouse genes Tbc1d10c
  • Rat genes Tbc1d10c
  • Zfish genes tbc1d10c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbc1d10c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TBC1D10C	IPI	UniProtKB:P26371	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D10C	IPI	UniProtKB:P49639	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D10C	IPI	UniProtKB:Q53G59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D10C	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D10C	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D10C	IPI	UniProtKB:Q53G59	Human	PMID:32296183
Cellular Component	GO:0031527	filopodium membrane	TBC1D10C	IDA		Human	PMID:17562788
Cellular Component	GO:0016020	membrane	TBC1D10C	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	TBC1D10C	IDA		Human	PMID:17562788
Biological Process	GO:0042113	B cell activation	Tbc1d10c	IGI	MGI:MGI:1932389	Mouse	PMID:23109291
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	Tbc1d10c	IMP	MGI:MGI:5578034	Mouse	PMID:23109291
Biological Process	GO:0070371	ERK1 and ERK2 cascade	Tbc1d10c	IMP		Mouse	PMID:23109291
Biological Process	GO:0050869	negative regulation of B cell activation	Tbc1d10c	IMP	MGI:MGI:5578034	Mouse	PMID:23109291
Biological Process	GO:0050869	negative regulation of B cell activation	Tbc1d10c	IGI	MGI:MGI:1932389	Mouse	PMID:23109291
Biological Process	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	Tbc1d10c	IMP	MGI:MGI:5578034	Mouse	PMID:23109291
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Tbc1d10c	IGI	MGI:MGI:1932389	Mouse	PMID:23109291
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Tbc1d10c	IMP		Mouse	PMID:23109291
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	TBC1D10C	IMP		Human	PMID:17562788

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern