Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBC1D5
  • Mouse genes Tbc1d5
  • Rat genes Tbc1d5
  • Zfish genes tbc1d5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbc1d5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035612	AP-2 adaptor complex binding	TBC1D5	IDA		Human	PMID:24603492
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:P60520	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q96CW1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q96QK1	Human	PMID:20923837
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9QZ88	Human	PMID:20923837
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9UBQ0	Human	PMID:20923837
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:O95166	Human	PMID:22354992
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:P60520	Human	PMID:22354992
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9BXW4	Human	PMID:22354992
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9GZQ8	Human	PMID:22354992
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9H0R8	Human	PMID:22354992
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9H492	Human	PMID:22354992
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:O75385	Human	PMID:24603492
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q7Z3C6	Human	PMID:24603492
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q96CW1	Human	PMID:24603492
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9UBQ0	Human	PMID:24603492
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q96QK1	Human	PMID:24980502
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q96QK1	Human	PMID:27385586
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:P60520	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q96CW1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:P24278	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:P60520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9BZP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9H0R8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:Q9UJT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D5	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0044877	protein-containing complex binding	TBC1D5	IDA		Human	PMID:19531583
Molecular Function	GO:1905394	retromer complex binding	TBC1D5	IMP		Human	PMID:27385586
Cellular Component	GO:0005776	autophagosome	TBC1D5	IDA		Human	PMID:22354992
Cellular Component	GO:0010008	endosome membrane	TBC1D5	IDA		Human	PMID:20923837
Cellular Component	GO:0005794	Golgi apparatus	TBC1D5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TBC1D5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030904	retromer complex	TBC1D5	IDA		Human	PMID:20923837
Biological Process	GO:0006914	autophagy	TBC1D5	IDA		Human	PMID:22354992
Biological Process	GO:0016236	macroautophagy	TBC1D5	IMP		Human	PMID:24603492
Biological Process	GO:0002092	positive regulation of receptor internalization	TBC1D5	IMP		Human	PMID:22354992
Biological Process	GO:0042594	response to starvation	TBC1D5	IDA		Human	PMID:22354992
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	TBC1D5	IMP		Human	PMID:22354992

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern