Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBC1D7
  • Mouse genes Tbc1d7
  • Rat genes Tbc1d7
  • Zfish genes tbc1d7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbc1d7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	TBC1D7	IDA		Human	PMID:17646400
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q92574	Human	PMID:17658474
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9H0R8	Human	PMID:22354992
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:O43805	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:O95751	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:P08727	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q96KN7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9BUZ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9H2G9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9UJC3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:O95429	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9BUZ4	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:O43805	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:P08727	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9BUZ4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9UJC3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:O43805	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:O95751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:P08727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:P09917	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:P23025	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q14145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q8TD10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9BUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9BVG3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9H3L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9NR46	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9UJC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TBC1D7	IPI	UniProtKB:Q9Y250	Human	PMID:32296183
Molecular Function	GO:0031267	small GTPase binding	TBC1D7	IPI	UniProtKB:Q9H0T7	Human	PMID:17646400
Cellular Component	GO:0036064	ciliary basal body	TBC1D7	IDA		Human	PMID:17646400
Cellular Component	GO:0031410	cytoplasmic vesicle	TBC1D7	IDA		Human	PMID:17658474
Cellular Component	GO:0033596	TSC1-TSC2 complex	TBC1D7	IPI		Human	PMID:22795129
Biological Process	GO:0090630	activation of GTPase activity	TBC1D7	IMP		Human	PMID:22795129
Biological Process	GO:0090630	activation of GTPase activity	Tbc1d7	IMP		Mouse	MGI:MGI:5437552|PMID:22795129
Biological Process	GO:1902018	negative regulation of cilium assembly	TBC1D7	IMP		Human	PMID:17646400
Biological Process	GO:0032007	negative regulation of TOR signaling	TBC1D7	IDA		Human	PMID:22795129
Biological Process	GO:0032007	negative regulation of TOR signaling	TBC1D7	IMP		Human	PMID:22795129
Biological Process	GO:0032007	negative regulation of TOR signaling	Tbc1d7	IMP		Mouse	MGI:MGI:5437552|PMID:22795129
Biological Process	GO:0043547	positive regulation of GTPase activity	TBC1D7	IDA		Human	PMID:17646400
Biological Process	GO:0031398	positive regulation of protein ubiquitination	TBC1D7	IDA		Human	PMID:17658474
Biological Process	GO:0070848	response to growth factor	TBC1D7	IMP		Human	PMID:22795129

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern