Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBL1XR1
  • Mouse genes Tbl1xr1
  • Rat genes Tbl1xr1
  • Zfish genes tbl1xr1a,tbl1xr1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbl1xr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	TBL1XR1	IPI	UniProtKB:P35222	Human	PMID:18193033
Molecular Function	GO:0003677	DNA binding	Tbl1xr1	IDA		Mouse	PMID:14980219
Molecular Function	GO:0042393	histone binding	TBL1XR1	IDA		Human	PMID:15601853
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:O75376	Human	PMID:12628926
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:Q9Y618	Human	PMID:16893456
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:P36404	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:P54253	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:Q60974	Human	PMID:28348241
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:P36404	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:O14645	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:P00441	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBL1XR1	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Tbl1xr1	IPI	UniProtKB:P51608	Mouse	MGI:MGI:5528617|PMID:23770565
Molecular Function	GO:0005515	protein binding	Tbl1xr1	IPI	UniProtKB:Q9Z2D6	Mouse	MGI:MGI:5904547|PMID:28348241
Molecular Function	GO:0005515	protein binding	Tbl1xr1	IPI	PR:P61080	Mouse	PMID:14980219
Molecular Function	GO:0000976	transcription cis-regulatory region binding	TBL1XR1	IDA		Human	PMID:18193033
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Tbl1xr1	IDA		Mouse	MGI:MGI:3604169|PMID:16127449
Molecular Function	GO:0003714	transcription corepressor activity	TBL1XR1	IDA		Human	PMID:12628926
Molecular Function	GO:0003714	transcription corepressor activity	TBL1XR1	IGI	UniProtKB:O60907	Human	PMID:15601853
Molecular Function	GO:0003714	transcription corepressor activity	Tbl1xr1	IMP		Mouse	PMID:14980219
Cellular Component	GO:0000118	histone deacetylase complex	TBL1XR1	IDA		Human	PMID:18326024
Cellular Component	GO:0072686	mitotic spindle	TBL1XR1	IDA		Human	PMID:18326024
Cellular Component	GO:0005634	nucleus	TBL1XR1	IDA		Human	PMID:18193033
Cellular Component	GO:0017053	transcription repressor complex	TBL1XR1	IDA		Human	PMID:12628926
Cellular Component	GO:0017053	transcription repressor complex	TBL1XR1	IDA		Human	PMID:15601853
Biological Process	GO:0060612	adipose tissue development	Tbl1xr1	IMP	MGI:MGI:5511131	Mouse	PMID:23499424
Biological Process	GO:0001835	blastocyst hatching	Tbl1xr1	IMP		Mouse	PMID:27869233
Biological Process	GO:0060613	fat pad development	Tbl1xr1	IMP	MGI:MGI:5511131	Mouse	PMID:23499424
Biological Process	GO:0016042	lipid catabolic process	Tbl1xr1	IMP	MGI:MGI:5511131	Mouse	PMID:23499424
Biological Process	GO:0035264	multicellular organism growth	Tbl1xr1	IMP	MGI:MGI:5511131	Mouse	PMID:23499424
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Tbl1xr1	IMP		Mouse	PMID:14980219
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TBL1XR1	IDA		Human	PMID:12628926
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	TBL1XR1	IMP		Human	PMID:18193033
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TBL1XR1	IDA		Human	PMID:18193033
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TBL1XR1	IDA		Human	PMID:18193033
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tbl1xr1	IMP		Mouse	MGI:MGI:3604169|PMID:16127449
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Tbl1xr1	IMP		Mouse	PMID:14980219
Biological Process	GO:0010468	regulation of gene expression	Tbl1xr1	IMP	MGI:MGI:5511131	Mouse	PMID:23499424
Biological Process	GO:0090207	regulation of triglyceride metabolic process	Tbl1xr1	IMP	MGI:MGI:5511131	Mouse	PMID:23499424
Biological Process	GO:0002021	response to dietary excess	Tbl1xr1	IMP	MGI:MGI:5511131	Mouse	PMID:23499424
Biological Process	GO:0050872	white fat cell differentiation	Tbl1xr1	IMP	MGI:MGI:5511131	Mouse	PMID:23499424

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern