Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBR1
  • Mouse genes Tbr1
  • Rat genes Tbr1
  • Zfish genes tbr1a,tbr1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	Tbr1	IDA		Mouse	PMID:30186101
Molecular Function	GO:0003677	DNA binding	Tbr1	IDA		Mouse	PMID:15584924
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Tbr1	IDA		Mouse	PMID:14999075
Molecular Function	GO:0005515	protein binding	TBR1	IPI	UniProtKB:Q9H334	Human	PMID:30250039
Molecular Function	GO:0005515	protein binding	TBR1	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBR1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBR1	IPI	UniProtKB:P05067-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBR1	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBR1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBR1	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TBR1	IPI	UniProtKB:P54253	Human	PMID:35140242
Molecular Function	GO:0019901	protein kinase binding	Tbr1	IPI	RGD:62004	Rat	PMID:10749215|RGD:11576295
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tbr1	IDA		Mouse	PMID:20615956
Cellular Component	GO:0005634	nucleus	TBR1	IDA		Human	PMID:25232744
Cellular Component	GO:0005634	nucleus	Tbr1	IDA		Mouse	PMID:14999075
Cellular Component	GO:0005634	nucleus	Tbr1	IDA		Mouse	PMID:16202707
Cellular Component	GO:0005634	nucleus	Tbr1	IDA		Rat	PMID:10749215|RGD:11576295
Biological Process	GO:0021764	amygdala development	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:24441682
Biological Process	GO:0021987	cerebral cortex development	Tbr1	IMP		Mouse	PMID:30186101
Biological Process	GO:0021987	cerebral cortex development	Tbr1	IEP		Rat	PMID:10749215|RGD:11576295
Biological Process	GO:0006338	chromatin remodeling	Tbr1	IMP		Mouse	PMID:30186101
Biological Process	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	Tbr1	IGI	MGI:MGI:2679336	Mouse	PMID:23144223
Biological Process	GO:0001661	conditioned taste aversion	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:24441682
Biological Process	GO:0010467	gene expression	Tbr1	IMP		Mouse	PMID:30186101
Biological Process	GO:0030902	hindbrain development	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:16540585
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TBR1	IDA		Human	PMID:25232744
Biological Process	GO:0030182	neuron differentiation	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:20615956
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tbr1	IDA		Mouse	PMID:15584924
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tbr1	IGI	MGI:MGI:1309489	Mouse	PMID:15584924
Biological Process	GO:1902667	regulation of axon guidance	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:24441682
Biological Process	GO:1902667	regulation of axon guidance	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:11967891
Biological Process	GO:0010468	regulation of gene expression	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:20615956
Biological Process	GO:0010975	regulation of neuron projection development	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:20615956
Biological Process	GO:0010092	specification of animal organ identity	Tbr1	IMP	MGI:MGI:2179766	Mouse	PMID:20615956

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern