Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tbx20

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TBX20
- Mouse genes Tbx20
- Rat genes Tbx20
- Zfish genes tbx20
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbx20

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Tbx20	IDA		Mouse	PMID:15843407
Molecular Function	GO:0003677	DNA binding	Tbx20	IDA		Mouse	PMID:14978031
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Tbx20	IDA		Mouse	MGI:MGI:5284807\|PMID:14550786
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Tbx20	IDA		Mouse	PMID:14978031
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Tbx20	IDA		Mouse	PMID:15843407
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	TBX20	IDA		Human	PMID:19762328
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Tbx20	IDA		Mouse	MGI:MGI:5284807\|PMID:14550786
Molecular Function	GO:0005515	protein binding	Tbx20	IPI	UniProtKB:Q000T4	Mouse	PMID:15843409
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tbx20	IDA		Mouse	MGI:MGI:5284807\|PMID:14550786
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	TBX20	IDA		Human	PMID:19762328
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Tbx20	IDA		Mouse	MGI:MGI:5284807\|PMID:14550786
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Tbx20	IPI	UniProtKB:P42582\|UniProtKB:P97489\|UniProtKB:Q08369	Mouse	MGI:MGI:5284807\|PMID:14550786
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Tbx20	IPI	UniProtKB:Q02591\|UniProtKB:Q9WUI0	Mouse	MGI:MGI:5448510\|PMID:22164283
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	TBX20	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Tbx20	IDA		Mouse	MGI:MGI:5284807\|PMID:14550786
Cellular Component	GO:0005634	nucleus	Tbx20	IDA		Mouse	MGI:MGI:5284807\|PMID:14550786
Biological Process	GO:0001525	angiogenesis	tbx20	IMP	ZFIN:ZDB-MRPHLNO-190405-3	Zfish	PMID:29545372
Biological Process	GO:0001525	angiogenesis	tbx20	IMP	ZFIN:ZDB-GENO-190807-5	Zfish	PMID:29545372
Biological Process	GO:0003176	aortic valve development	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0003180	aortic valve morphogenesis	TBX20	IMP		Human	PMID:18275040
Biological Process	GO:0003180	aortic valve morphogenesis	TBX20	IMP		Human	PMID:18834961
Biological Process	GO:0060413	atrial septum morphogenesis	TBX20	IMP		Human	PMID:17668378
Biological Process	GO:0060413	atrial septum morphogenesis	TBX20	IMP		Human	PMID:18834961
Biological Process	GO:0060413	atrial septum morphogenesis	TBX20	IMP		Human	PMID:19762328
Biological Process	GO:0036302	atrioventricular canal development	Tbx20	IMP		Mouse	MGI:MGI:5299248\|PMID:21983003
Biological Process	GO:0003171	atrioventricular valve development	Tbx20	IMP		Mouse	MGI:MGI:5299248\|PMID:21983003
Biological Process	GO:0008015	blood circulation	Tbx20	IMP	MGI:MGI:3579836	Mouse	PMID:15843414
Biological Process	GO:0001568	blood vessel development	tbx20	IMP	ZFIN:ZDB-MRPHLNO-070226-1	Zfish	PMID:12397116
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Tbx20	IMP	MGI:MGI:3579836	Mouse	PMID:15843414
Biological Process	GO:0003207	cardiac chamber formation	Tbx20	IMP		Mouse	MGI:MGI:3579960\|PMID:15901664
Biological Process	GO:0003207	cardiac chamber formation	Tbx20	IMP	MGI:MGI:3580099	Mouse	PMID:19661464
Biological Process	GO:0060038	cardiac muscle cell proliferation	tbx20	IMP		Zfish	PMID:27940156
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0003215	cardiac right ventricle morphogenesis	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0003279	cardiac septum development	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0008283	cell population proliferation	Tbx20	IMP	MGI:MGI:3579849	Mouse	PMID:15843407
Biological Process	GO:0035844	cloaca development	tbx20	IMP	ZFIN:ZDB-MRPHLNO-070226-1	Zfish	PMID:16672335
Biological Process	GO:0009953	dorsal/ventral pattern formation	Tbx20	IMP	MGI:MGI:3580099	Mouse	PMID:15901664
Biological Process	GO:0035050	embryonic heart tube development	Tbx20	IGI	MGI:MGI:97350	Mouse	PMID:15843414
Biological Process	GO:0035050	embryonic heart tube development	Tbx20	IMP	MGI:MGI:3579836	Mouse	PMID:15843414
Biological Process	GO:0035050	embryonic heart tube development	tbx20	IMP	ZFIN:ZDB-MRPHLNO-070226-2	Zfish	PMID:12397116
Biological Process	GO:0035050	embryonic heart tube development	tbx20	IMP	ZFIN:ZDB-MRPHLNO-070226-1	Zfish	PMID:12397116
Biological Process	GO:0036306	embryonic heart tube elongation	Tbx20	IMP		Mouse	MGI:MGI:3579960\|PMID:15901664
Biological Process	GO:0003143	embryonic heart tube morphogenesis	Tbx20	IMP		Mouse	MGI:MGI:3579960\|PMID:15901664
Biological Process	GO:0035162	embryonic hemopoiesis	tbx20	IMP	ZFIN:ZDB-MRPHLNO-070226-1	Zfish	PMID:12397116
Biological Process	GO:0003272	endocardial cushion formation	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0003272	endocardial cushion formation	Tbx20	IMP		Mouse	MGI:MGI:5299248\|PMID:21983003
Biological Process	GO:0003203	endocardial cushion morphogenesis	Tbx20	IMP		Mouse	MGI:MGI:3579960\|PMID:15901664
Biological Process	GO:0035922	foramen ovale closure	TBX20	IMP		Human	PMID:19762328
Biological Process	GO:0007507	heart development	tbx20	IMP	ZFIN:ZDB-GENO-171221-1	Zfish	PMID:27907103
Biological Process	GO:0007507	heart development	tbx20	IMP	ZFIN:ZDB-MRPHLNO-171219-2	Zfish	PMID:27907103
Biological Process	GO:0007507	heart development	tbx20	IEP		Zfish	PMID:10906473
Biological Process	GO:0007507	heart development	tbx20	IMP	ZFIN:ZDB-MRPHLNO-171219-3	Zfish	PMID:27907103
Biological Process	GO:0007507	heart development	tbx20	IMP	ZFIN:ZDB-GENO-170309-3	Zfish	PMID:27940156
Biological Process	GO:0007507	heart development	tbx20	IEP		Zfish	PMID:10656766
Biological Process	GO:0001947	heart looping	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0001947	heart looping	Tbx20	IMP	MGI:MGI:3579849	Mouse	PMID:15843407
Biological Process	GO:0001947	heart looping	Tbx20	IMP	MGI:MGI:3580099	Mouse	PMID:15901664
Biological Process	GO:0001947	heart looping	tbx20	IMP	ZFIN:ZDB-MRPHLNO-070226-1	Zfish	PMID:12397116
Biological Process	GO:0003313	heart rudiment development	tbx20	IMP	ZFIN:ZDB-GENO-170309-3	Zfish	PMID:27940156
Biological Process	GO:0014031	mesenchymal cell development	Tbx20	IMP		Mouse	MGI:MGI:5299248\|PMID:21983003
Biological Process	GO:0097475	motor neuron migration	Tbx20	IMP	MGI:MGI:2386545,MGI:MGI:3579499	Mouse	PMID:17119020
Biological Process	GO:0006936	muscle contraction	Tbx20	IMP	MGI:MGI:3579836	Mouse	PMID:15843414
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Tbx20	IDA		Mouse	PMID:15843407
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Tbx20	IDA		Mouse	PMID:14978031
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	tbx20	IMP	ZFIN:ZDB-MRPHLNO-070226-1	Zfish	PMID:18407257
Biological Process	GO:0010991	negative regulation of SMAD protein complex assembly	Tbx20	IDA		Mouse	PMID:19661464
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Tbx20	IMP		Mouse	MGI:MGI:3579960\|PMID:15901664
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Tbx20	IGI	MGI:MGI:894293	Mouse	PMID:19661464
Biological Process	GO:0003151	outflow tract morphogenesis	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0003148	outflow tract septum morphogenesis	TBX20	IMP		Human	PMID:18275040
Biological Process	GO:0003148	outflow tract septum morphogenesis	TBX20	IMP		Human	PMID:18834961
Biological Process	GO:0003148	outflow tract septum morphogenesis	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0003344	pericardium morphogenesis	Tbx20	IMP		Mouse	MGI:MGI:3579960\|PMID:15901664
Biological Process	GO:0043065	positive regulation of apoptotic process	Tbx20	IMP		Rat	PMID:27572266\|RGD:155882587
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Tbx20	IMP		Mouse	MGI:MGI:5299248\|PMID:21983003
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	Tbx20	IMP		Mouse	MGI:MGI:3579960\|PMID:15901664
Biological Process	GO:0090068	positive regulation of cell cycle process	Tbx20	IMP		Rat	PMID:27572266\|RGD:155882587
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Tbx20	IDA		Mouse	PMID:15843409
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Tbx20	IDA		Mouse	PMID:15843407
Biological Process	GO:0010718	positive regulation of epithelial to mesenchymal transition	Tbx20	IMP		Mouse	MGI:MGI:5299248\|PMID:21983003
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tbx20	IDA		Mouse	MGI:MGI:5284807\|PMID:14550786
Biological Process	GO:0003193	pulmonary valve formation	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0060577	pulmonary vein morphogenesis	TBX20	IMP		Human	PMID:18834961
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	tbx20	IMP	ZFIN:ZDB-GENO-171221-1	Zfish	PMID:27907103
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	tbx20	IMP	ZFIN:ZDB-MRPHLNO-171219-2	Zfish	PMID:27907103
Biological Process	GO:0003175	tricuspid valve development	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409
Biological Process	GO:0001570	vasculogenesis	tbx20	IMP	ZFIN:ZDB-MRPHLNO-070226-1	Zfish	PMID:12397116
Biological Process	GO:0021524	visceral motor neuron differentiation	Tbx20	IMP		Mouse	MGI:MGI:3604925\|PMID:15843409

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.