Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TCF15
  • Mouse genes Tcf15
  • Rat genes Tcf15
  • Zfish genes tcf15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tcf15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	Tcf15	IPI	UniProtKB:P15806	Mouse	MGI:MGI:6508503|PMID:23395635
Molecular Function	GO:0043425	bHLH transcription factor binding	Tcf15	IPI	UniProtKB:P15806	Mouse	MGI:MGI:6508495|PMID:15226298
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Tcf15	IDA		Mouse	MGI:MGI:3818123|PMID:18361414
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Tcf15	IDA		Mouse	MGI:MGI:6508495|PMID:15226298
Molecular Function	GO:0070888	E-box binding	Tcf15	IDA		Mouse	MGI:MGI:6508495|PMID:15226298
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tcf15	IDA		Mouse	MGI:MGI:3818123|PMID:18361414
Cellular Component	GO:0005634	nucleus	Tcf15	IMP		Mouse	MGI:MGI:6508503|PMID:23395635
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Tcf15	IDA		Mouse	MGI:MGI:3818123|PMID:18361414
Biological Process	GO:0009952	anterior/posterior pattern specification	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:0043583	ear development	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:0045198	establishment of epithelial cell apical/basal polarity	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:24038871
Biological Process	GO:0060231	mesenchymal to epithelial transition	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:24038871
Biological Process	GO:0007517	muscle organ development	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:0048644	muscle organ morphogenesis	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:1902037	negative regulation of hematopoietic stem cell differentiation	Tcf15	IDA		Mouse	MGI:MGI:6479302|PMID:32669716
Biological Process	GO:0050884	neuromuscular process controlling posture	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:0048339	paraxial mesoderm development	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:2000738	positive regulation of stem cell differentiation	Tcf15	IMP		Mouse	MGI:MGI:6508503|PMID:23395635
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tcf15	IDA		Mouse	MGI:MGI:3818123|PMID:18361414
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tcf15	IDA		Mouse	MGI:MGI:6508495|PMID:15226298
Biological Process	GO:0036342	post-anal tail morphogenesis	Tcf15	IMP	MGI:MGI:1928775	Mouse	PMID:8955271
Biological Process	GO:1903053	regulation of extracellular matrix organization	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:24038871
Biological Process	GO:0010468	regulation of gene expression	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:24038871
Biological Process	GO:0003016	respiratory system process	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:0048705	skeletal system morphogenesis	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:0001756	somitogenesis	Tcf15	IMP	MGI:MGI:1929775	Mouse	PMID:8955271
Biological Process	GO:0019827	stem cell population maintenance	Tcf15	IDA		Mouse	MGI:MGI:6479302|PMID:32669716

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern