Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TCL1A
  • Mouse genes Tcl1
  • Rat genes Tcl1a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tcl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TCL1A	IDA		Human	PMID:10983986
Molecular Function	GO:0042802	identical protein binding	TCL1A	IPI	UniProtKB:P56279	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	TCL1A	IPI	UniProtKB:P56279	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13137	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q8TCS8	Human	PMID:16934922
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P01100	Human	PMID:19064921
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P05412	Human	PMID:19064921
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P17275	Human	PMID:19064921
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q09472	Human	PMID:19064921
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13137	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:A2RRN7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:B0LPE5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:O94967	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P15884	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P40222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P62310	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13625-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q53EZ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q6PID6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q8N3L3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q96Q35	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q9H257	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q9NRG1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q9Y6K1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P31749	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:A0A0S2Z3D6	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P31749	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q08379	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13077	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q53EZ4	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q96HA8	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P31749	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P31749	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13137	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q6PID6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q9Y6K1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:A2RRN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:O95271	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P25963	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P40222	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:P62310	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q13137	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q6PID6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q86VP1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q8IYE1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q8NI38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q96FX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q96KQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q96N21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q9GZT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q9NRG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TCL1A	IPI	UniProtKB:Q9Y6K1	Human	PMID:32296183
Molecular Function	GO:0019901	protein kinase binding	TCL1A	IPI	UniProtKB:P31749	Human	PMID:10983986
Molecular Function	GO:0019901	protein kinase binding	TCL1A	IPI	UniProtKB:P31751	Human	PMID:10983986
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	TCL1A	IMP		Human	PMID:10983986
Cellular Component	GO:0005938	cell cortex	Tcl1	IDA		Mouse	PMID:12181493
Cellular Component	GO:0005829	cytosol	TCL1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	TCL1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TCL1A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Tcl1	IDA		Mouse	PMID:12181493
Cellular Component	GO:1990917	ooplasm	Tcl1	IDA		Mouse	PMID:12181493
Cellular Component	GO:0045120	pronucleus	Tcl1	IDA		Mouse	PMID:12181493
Cellular Component	GO:0032991	protein-containing complex	TCL1A	IMP		Human	PMID:10983986
Biological Process	GO:0032148	activation of protein kinase B activity	Tcl1	IMP		Mouse	MGI:MGI:6377804|PMID:28262547
Biological Process	GO:0071356	cellular response to tumor necrosis factor	TCL1A	IDA		Human	PMID:10983986
Biological Process	GO:0043066	negative regulation of apoptotic process	TCL1A	IDA		Human	PMID:10983986
Biological Process	GO:0010629	negative regulation of gene expression	Tcl1	IMP		Mouse	PMID:17938240
Biological Process	GO:0008284	positive regulation of cell population proliferation	TCL1A	IDA		Human	PMID:10983986
Biological Process	GO:0010918	positive regulation of mitochondrial membrane potential	TCL1A	IDA		Human	PMID:10983986
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	TCL1A	IMP		Human	PMID:10983986
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	TCL1A	IDA		Human	PMID:10983986
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	TCL1A	IDA		Human	PMID:10983986
Biological Process	GO:2000036	regulation of stem cell population maintenance	Tcl1	IGI	MGI:MGI:2446210	Mouse	PMID:17938240
Biological Process	GO:0035019	somatic stem cell population maintenance	Tcl1	IMP		Mouse	PMID:16767105

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern