Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TDO2
  • Mouse genes Tdo2
  • Rat genes Tdo2
  • Zfish genes tdo2a,tdo2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tdo2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Tdo2	IDA		Rat	PMID:10719243|RGD:2290190
Molecular Function	GO:0016597	amino acid binding	Tdo2	IDA		Rat	PMID:3899109|RGD:2291804
Molecular Function	GO:0016597	amino acid binding	Tdo2	IDA		Rat	PMID:7236232|RGD:2303721
Molecular Function	GO:0020037	heme binding	TDO2	IDA		Human	PMID:27762317
Molecular Function	GO:0020037	heme binding	TDO2	IDA		Human	PMID:28285122
Molecular Function	GO:0020037	heme binding	Tdo2	IDA		Rat	PMID:3400092|RGD:2290313
Molecular Function	GO:0042802	identical protein binding	TDO2	IPI	UniProtKB:P48775	Human	PMID:24722188
Molecular Function	GO:0042802	identical protein binding	TDO2	IPI	UniProtKB:P48775	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	TDO2	IPI	UniProtKB:P48775	Human	PMID:32296183
Molecular Function	GO:0019825	oxygen binding	Tdo2	IDA		Rat	PMID:10719243|RGD:2290190
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O95671	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O00560	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O95671	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:P06730	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9HAN9	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O60762	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O95671	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:P06730	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q68DK2-5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q70IA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9H190	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9H8S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9NPG2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O60762	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O95671	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9H190	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O95671	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:P20393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q68DK2-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q8IYS1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9H8S9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9HAN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9NPG2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:O43865	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:P12830	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:P27797	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:P36957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TDO2	IPI	UniProtKB:Q8TDX7	Human	PMID:32814053
Molecular Function	GO:0004833	tryptophan 2,3-dioxygenase activity	TDO2	IDA		Human	PMID:27762317
Molecular Function	GO:0004833	tryptophan 2,3-dioxygenase activity	TDO2	IDA		Human	PMID:28285122
Molecular Function	GO:0004833	tryptophan 2,3-dioxygenase activity	Tdo2	IDA		Rat	PMID:10719243|RGD:2290190
Molecular Function	GO:0004833	tryptophan 2,3-dioxygenase activity	Tdo2	IDA		Rat	PMID:3400092|RGD:2290313
Molecular Function	GO:0004833	tryptophan 2,3-dioxygenase activity	Tdo2	IDA		Rat	PMID:3899109|RGD:2291804
Molecular Function	GO:0004833	tryptophan 2,3-dioxygenase activity	Tdo2	IDA		Rat	PMID:7236232|RGD:2303721
Biological Process	GO:0051289	protein homotetramerization	TDO2	IDA		Human	PMID:27762317
Biological Process	GO:0051289	protein homotetramerization	TDO2	IDA		Human	PMID:28285122
Biological Process	GO:1904842	response to nitroglycerin	Tdo2	IEP		Rat	PMID:28659861|RGD:13601983
Biological Process	GO:0019442	tryptophan catabolic process to acetyl-CoA	Tdo2	IDA		Rat	PMID:7236232|RGD:2303721
Biological Process	GO:0019441	tryptophan catabolic process to kynurenine	TDO2	IDA		Human	PMID:27762317
Biological Process	GO:0006568	tryptophan metabolic process	Tdo2	IDA		Rat	PMID:10719243|RGD:2290190
Biological Process	GO:0006568	tryptophan metabolic process	Tdo2	IDA		Rat	PMID:3400092|RGD:2290313
Biological Process	GO:0006568	tryptophan metabolic process	Tdo2	IDA		Rat	PMID:3899109|RGD:2291804

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern