Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TEAD2
  • Mouse genes Tead2
  • Rat genes Tead2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tead2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097718	disordered domain specific binding	TEAD2	IMP		Human	PMID:20368466
Molecular Function	GO:0003677	DNA binding	Tead2	IDA		Mouse	PMID:7629195
Molecular Function	GO:0003677	DNA binding	Tead2	IDA		Mouse	PMID:9502435
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TEAD2	IDA		Human	PMID:18579750
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TEAD2	IDA		Human	PMID:19324877
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TEAD2	IMP		Human	PMID:20368466
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Tead2	IDA		Mouse	PMID:21385842
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Tead2	IDA		Mouse	PMID:14736747
Molecular Function	GO:0005515	protein binding	TEAD2	IPI	UniProtKB:P46937	Human	PMID:18579750
Molecular Function	GO:0005515	protein binding	TEAD2	IPI	UniProtKB:Q9GZV5	Human	PMID:19324877
Molecular Function	GO:0005515	protein binding	TEAD2	IPI	UniProtKB:P46937	Human	PMID:20368466
Molecular Function	GO:0005515	protein binding	TEAD2	IPI	UniProtKB:Q15853	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TEAD2	IPI	UniProtKB:Q5TBC7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TEAD2	IPI	UniProtKB:P46937	Human	PMID:25751139
Molecular Function	GO:0005515	protein binding	TEAD2	IPI	UniProtKB:P46937	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Tead2	IPI	PR:P70365	Mouse	PMID:10934189
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tead2	IDA		Mouse	PMID:16207754
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	TEAD2	IDA		Human	PMID:28473536
Molecular Function	GO:0001223	transcription coactivator binding	TEAD2	IPI	UniProtKB:P46937	Human	PMID:20368466
Cellular Component	GO:0005829	cytosol	TEAD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	TEAD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TEAD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0140552	TEAD-YAP complex	TEAD2	IDA		Human	PMID:20368466
Cellular Component	GO:0005667	transcription regulator complex	Tead2	IDA		Mouse	PMID:16207754
Biological Process	GO:0071300	cellular response to retinoic acid	Tead2	IDA		Mouse	PMID:21385842
Biological Process	GO:0003143	embryonic heart tube morphogenesis	Tead2	IGI	MGI:MGI:101876	Mouse	PMID:18332127
Biological Process	GO:0003143	embryonic heart tube morphogenesis	Tead2	IGI	MGI:MGI:103262	Mouse	PMID:18332127
Biological Process	GO:0035329	hippo signaling	TEAD2	IDA		Human	PMID:18579750
Biological Process	GO:0035329	hippo signaling	TEAD2	IDA		Human	PMID:19324877
Biological Process	GO:0048368	lateral mesoderm development	Tead2	IGI	MGI:MGI:101876	Mouse	PMID:18332127
Biological Process	GO:0048368	lateral mesoderm development	Tead2	IGI	MGI:MGI:103262	Mouse	PMID:18332127
Biological Process	GO:0060548	negative regulation of cell death	Tead2	IGI	UniProtKB:Q06831|UniProtKB:Q7M6Y2	Mouse	MGI:MGI:5285157|PMID:20596238
Biological Process	GO:0001843	neural tube closure	Tead2	IMP	MGI:MGI:3763367	Mouse	PMID:17868131
Biological Process	GO:0030903	notochord development	Tead2	IGI	MGI:MGI:103262	Mouse	PMID:18332127
Biological Process	GO:0030903	notochord development	Tead2	IGI	MGI:MGI:101876	Mouse	PMID:18332127
Biological Process	GO:0048339	paraxial mesoderm development	Tead2	IGI	MGI:MGI:101876	Mouse	PMID:18332127
Biological Process	GO:0048339	paraxial mesoderm development	Tead2	IGI	MGI:MGI:103262	Mouse	PMID:18332127
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TEAD2	IMP		Human	PMID:20368466
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tead2	IDA		Mouse	PMID:9502435
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tead2	IDA		Mouse	PMID:14736747
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tead2	IDA		Mouse	PMID:21385842
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tead2	IGI	MGI:MGI:103262	Mouse	PMID:16207754
Biological Process	GO:0065003	protein-containing complex assembly	TEAD2	IMP		Human	PMID:20368466
Biological Process	GO:2000736	regulation of stem cell differentiation	Tead2	IMP		Mouse	PMID:21385842
Biological Process	GO:0006366	transcription by RNA polymerase II	Tead2	IDA		Mouse	PMID:14736747
Biological Process	GO:0001570	vasculogenesis	Tead2	IGI	MGI:MGI:101876	Mouse	PMID:18332127
Biological Process	GO:0001570	vasculogenesis	Tead2	IGI	MGI:MGI:103262	Mouse	PMID:18332127

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern