Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Terf2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TERF2
- Mouse genes Terf2
- Rat genes Terf2
- Zfish genes terfa
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Terf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	TERF2	IDA		Human	PMID:18812185
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	TERF2	IDA		Human	PMID:21852327
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	Terf2	IMP		Mouse	MGI:MGI:1097302\|PMID:9326950
Molecular Function	GO:0019899	enzyme binding	TERF2	IPI	UniProtKB:Q9H816	Human	PMID:20479256
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	TERF2	IDA		Human	PMID:17694070
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P12956	Human	PMID:10984620
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P54132	Human	PMID:12181313
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q14191	Human	PMID:12181313
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P07992	Human	PMID:14690602
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q92889	Human	PMID:14690602
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9BSI4	Human	PMID:15181449
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P54132	Human	PMID:15229185
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q13315	Human	PMID:15314656
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9BSI4-3	Human	PMID:15383534
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NUX5	Human	PMID:15383534
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:15383534
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NUX5	Human	PMID:15657433
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9H816	Human	PMID:16730175
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P03211	Human	PMID:16799465
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q13415	Human	PMID:16799465
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q13416	Human	PMID:16799465
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9BSI4	Human	PMID:16880378
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:16880378
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:17055345
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9BSI4	Human	PMID:18202258
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9H816	Human	PMID:18202258
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q80W00	Human	PMID:19287395
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q8NEM0	Human	PMID:19287395
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9BSI4	Human	PMID:19287395
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NUX5	Human	PMID:19287395
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:19287395
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q8IY92	Human	PMID:19596235
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q8IY92	Human	PMID:19596236
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NUX5	Human	PMID:19651898
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:19651898
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q80W00	Human	PMID:20360068
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9H816	Human	PMID:20479256
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9H816	Human	PMID:20655466
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:O94992	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P05204	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P16104	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P26373	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q69YI7	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q6PK04	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q7Z4V5	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q86VM9	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NR30	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9H816	Human	PMID:21217703
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:21217703
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P16104	Human	PMID:21824286
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:21829167
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:O94761	Human	PMID:22039056
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P16104	Human	PMID:22157895
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q8IY92	Human	PMID:24012755
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P12956	Human	PMID:24095731
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:24095731
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9H816	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P02545-1	Human	PMID:25399868
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:P02545-2	Human	PMID:25399868
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:25620558
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NZ71	Human	PMID:25620558
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9BSI4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9H816	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NUX5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NYB0	Human	PMID:27214791
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q9NUX5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TERF2	IPI	UniProtKB:Q96DT7	Human	PMID:30629181
Molecular Function	GO:0005515	protein binding	Terf2	IPI	UniProtKB:Q6ZQJ5	Mouse	MGI:MGI:5499273\|PMID:23604072
Molecular Function	GO:0005515	protein binding	Terf2	IPI	UniProtKB:Q91VL8	Mouse	MGI:MGI:4821187\|PMID:20622870
Molecular Function	GO:0005515	protein binding	Terf2	IPI	UniProtKB:Q8C7W7	Mouse	MGI:MGI:4830207\|PMID:20619712
Molecular Function	GO:0005515	protein binding	Terf2	IPI	UniProtKB:Q9NZ71	Mouse	MGI:MGI:5630027\|PMID:25620558
Molecular Function	GO:0005515	protein binding	Terf2	IPI	UniProtKB:Q91VL8	Mouse	MGI:MGI:4440768\|PMID:20339076
Molecular Function	GO:0042803	protein homodimerization activity	TERF2	IPI	UniProtKB:Q15554	Human	PMID:9326950
Molecular Function	GO:0042803	protein homodimerization activity	Terf2	IPI	UniProtKB:O35144	Mouse	MGI:MGI:1097302\|PMID:9326950
Molecular Function	GO:0044877	protein-containing complex binding	TERF2	IPI	ComplexPortal:CPX-478	Human	PMID:14690602
Molecular Function	GO:0044877	protein-containing complex binding	TERF2	IPI	ComplexPortal:CPX-1993	Human	PMID:24095731
Molecular Function	GO:0044877	protein-containing complex binding	Terf2	IPI	ComplexPortal:CPX-491	Mouse	MGI:MGI:3758502\|PMID:14690602
Molecular Function	GO:0003720	telomerase activity	TERF2	IDA		Human	PMID:23685356
Molecular Function	GO:0042162	telomeric DNA binding	TERF2	IDA		Human	PMID:19854130
Molecular Function	GO:0042162	telomeric DNA binding	TERF2	IDA		Human	PMID:20655466
Molecular Function	GO:0042162	telomeric DNA binding	TERF2	IDA		Human	PMID:23685356
Molecular Function	GO:0042162	telomeric DNA binding	Terf2	IDA		Mouse	MGI:MGI:5500098\|PMID:23685356
Molecular Function	GO:0042162	telomeric DNA binding	terfa	IDA		Zfish	PMID:33984809
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2	IDA		Human	PMID:12768206
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2	IDA		Human	PMID:15109494
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2	HDA		Human	PMID:19135898
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2	IDA		Human	PMID:20479256
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2	IDA		Human	PMID:20655466
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2	IDA		Human	PMID:23685356
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2	IDA		Human	PMID:24012755
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2	IDA		Human	PMID:24270157
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2	IDA		Mouse	MGI:MGI:5500098\|PMID:23685356
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2	IDA		Mouse	MGI:MGI:5705225\|PMID:15109494
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2	IDA		Mouse	PMID:17696610
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2	IDA		Mouse	PMID:15968270
Cellular Component	GO:0001673	male germ cell nucleus	Terf2	IDA		Mouse	PMID:17696610
Cellular Component	GO:0016604	nuclear body	TERF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000783	nuclear telomere cap complex	TERF2	IDA		Human	PMID:15181449
Cellular Component	GO:0000783	nuclear telomere cap complex	TERF2	IDA		Human	PMID:16880378
Cellular Component	GO:0005654	nucleoplasm	TERF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TERF2	IDA		Human	PMID:17055345
Cellular Component	GO:0070187	shelterin complex	TERF2	IPI		Human	PMID:15383534
Cellular Component	GO:0070187	shelterin complex	TERF2	IDA		Human	PMID:15383534
Cellular Component	GO:0070187	shelterin complex	TERF2	IMP		Human	PMID:21852327
Cellular Component	GO:0070187	shelterin complex	TERF2	IDA		Human	PMID:23685356
Cellular Component	GO:0000782	telomere cap complex	Terf2	IDA		Mouse	PMID:28031483
Biological Process	GO:0008089	anterograde axonal transport	Terf2	IMP		Mouse	MGI:MGI:5704269\|PMID:26586091
Biological Process	GO:0099088	axonal transport of messenger ribonucleoprotein complex	Terf2	IDA		Rat	PMID:26586091\|RGD:13702251
Biological Process	GO:0099088	axonal transport of messenger ribonucleoprotein complex	Terf2	IMP		Rat	PMID:26586091\|RGD:13702251
Biological Process	GO:0001701	in utero embryonic development	Terf2	IMP	MGI:MGI:3619525	Mouse	PMID:15968270
Biological Process	GO:1903770	negative regulation of beta-galactosidase activity	TERF2	IDA		Human	PMID:11927518
Biological Process	GO:2000773	negative regulation of cellular senescence	TERF2	IMP		Human	PMID:11927518
Biological Process	GO:1905778	negative regulation of exonuclease activity	TERF2	IDA		Human	PMID:15200954
Biological Process	GO:0010629	negative regulation of gene expression	TERF2	IMP		Human	PMID:11927518
Biological Process	GO:1904430	negative regulation of t-circle formation	TERF2	IMP		Human	PMID:15507207
Biological Process	GO:1904354	negative regulation of telomere capping	TERF2	IMP		Human	PMID:24270157
Biological Process	GO:0032205	negative regulation of telomere maintenance	TERF2	IDA		Human	PMID:17055345
Biological Process	GO:0032208	negative regulation of telomere maintenance via recombination	TERF2	IMP		Human	PMID:15507207
Biological Process	GO:0032208	negative regulation of telomere maintenance via recombination	Terf2	IMP		Mouse	MGI:MGI:5883205\|PMID:24120135
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	TERF2	IMP		Human	PMID:11971978
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	TERF2	IDA		Human	PMID:17055345
Biological Process	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	TERF2	IMP		Human	PMID:24012755
Biological Process	GO:1905839	negative regulation of telomeric D-loop disassembly	TERF2	IDA		Human	PMID:15200954
Biological Process	GO:0010628	positive regulation of gene expression	TERF2	IMP		Human	PMID:11927518
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	TERF2	IMP		Human	PMID:11927518
Biological Process	GO:0032206	positive regulation of telomere maintenance	TERF2	IDA		Human	PMID:24012755
Biological Process	GO:0032206	positive regulation of telomere maintenance	Terf2	IDA		Mouse	PMID:15968270
Biological Process	GO:0032206	positive regulation of telomere maintenance	Terf2	IMP	MGI:MGI:3619525	Mouse	PMID:15968270
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	TERF2	IMP		Human	PMID:14690602
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	TERF2	IMP		Human	PMID:17499040
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	TERF2	IPI	ComplexPortal:CPX-1993	Human	PMID:24095731
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	Terf2	IMP		Mouse	MGI:MGI:4830207\|PMID:20619712
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	Terf2	IMP		Mouse	MGI:MGI:5883205\|PMID:24120135
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	Terf2	IDA		Mouse	PMID:15968270
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	Terf2	IMP	MGI:MGI:3619525	Mouse	PMID:15968270
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	TERF2	IMP		Human	PMID:17499040
Biological Process	GO:0032204	regulation of telomere maintenance	TERF2	IMP		Human	PMID:22536324
Biological Process	GO:0032210	regulation of telomere maintenance via telomerase	TERF2	IMP		Human	PMID:19864690
Biological Process	GO:0032210	regulation of telomere maintenance via telomerase	TERF2	IDA		Human	PMID:23685356
Biological Process	GO:0016233	telomere capping	TERF2	IMP		Human	PMID:12768206
Biological Process	GO:0016233	telomere capping	TERF2	IMP		Human	PMID:14690602
Biological Process	GO:0016233	telomere capping	TERF2	IMP		Human	PMID:15657433
Biological Process	GO:0016233	telomere capping	TERF2	IDA		Human	PMID:21852327
Biological Process	GO:0000723	telomere maintenance	TERF2	IMP		Human	PMID:20655466
Biological Process	GO:0000723	telomere maintenance	Terf2	IDA		Mouse	PMID:15968270
Biological Process	GO:0000723	telomere maintenance	Terf2	IMP	MGI:MGI:3619525	Mouse	PMID:15968270
Biological Process	GO:0000723	telomere maintenance	Terf2	IMP		Mouse	PMID:15010310
Biological Process	GO:0061820	telomeric D-loop disassembly	TERF2	IGI	UniProtKB:O94761	Human	PMID:22039056
Biological Process	GO:0031627	telomeric loop formation	TERF2	IDA		Human	PMID:10338214
Biological Process	GO:0031627	telomeric loop formation	Terf2	IMP		Mouse	MGI:MGI:5883205\|PMID:24120135

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.