Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TERF2IP
  • Mouse genes Terf2ip
  • Rat genes Terf2ip
  • Zfish genes terf2ip
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Terf2ip

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	TERF2IP	IDA		Human	PMID:17694070
Molecular Function	GO:0019902	phosphatase binding	TERF2IP	IPI	UniProtKB:O75365	Human	PMID:23178297
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q92889	Human	PMID:14690602
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9BSI4	Human	PMID:15181449
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P12956	Human	PMID:15383534
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:15383534
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9BSI4-3	Human	PMID:15383534
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:16880378
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:17055345
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:19287395
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q8IY92	Human	PMID:19596235
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:19651898
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O00479	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O14604	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O15347	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O60218	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O75347	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O75884	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O95154	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O95336	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:O95848	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P06454	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P09936	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P12104	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P12956	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P14550	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P18510	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P25713	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P25815	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P27482	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P28340	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P31749	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P37837	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P46108	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P47224	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P48539	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P49321	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P49736	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P61964	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P61978	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P80297	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q13069	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q13155	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q13363	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q14019	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q14135	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q14980	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15121	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q16775	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q5H9R7	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q5JTV8	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q6IBS0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q6ZVK8	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q8IYL3	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q8N8S7	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q8TAQ2	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q8TE68	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q8WW12	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q92620	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q92917	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q96A72	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q96B86	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q96E09	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q96FN4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q96GT9	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q96I15	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q96IQ9	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9BQE9	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9BUL9	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9BXM0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9NS86	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9NWV8	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9NZ63	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9NZT2	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9UKD2	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9UQN3	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9Y5U2	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:21217703
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:21829167
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:24095731
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:25620558
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q9NZ71	Human	PMID:25620558
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:P12956	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	TERF2IP	IPI	UniProtKB:Q15554	Human	PMID:27214791
Molecular Function	GO:0005515	protein binding	Terf2ip	IPI	UniProtKB:O35144|UniProtKB:O88351|UniProtKB:O88522|UniProtKB:Q60680	Mouse	MGI:MGI:4821187|PMID:20622870
Molecular Function	GO:0005515	protein binding	Terf2ip	IPI	UniProtKB:O35144	Mouse	MGI:MGI:4440768|PMID:20339076
Molecular Function	GO:0042162	telomeric DNA binding	TERF2IP	IDA		Human	PMID:23685356
Molecular Function	GO:0042162	telomeric DNA binding	Terf2ip	IDA		Mouse	MGI:MGI:5500098|PMID:23685356
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2IP	IDA		Human	PMID:12768206
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2IP	IDA		Human	PMID:14565979
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2IP	IDA		Human	PMID:15109494
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2IP	HDA		Human	PMID:19135898
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2IP	IDA		Human	PMID:21076401
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2IP	IDA		Human	PMID:23685356
Cellular Component	GO:0000781	chromosome, telomeric region	TERF2IP	IDA		Human	PMID:24270157
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2ip	IDA		Mouse	MGI:MGI:5500098|PMID:23685356
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2ip	IDA		Mouse	MGI:MGI:5705225|PMID:15109494
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2ip	IMP		Mouse	MGI:MGI:4839412|PMID:20622869
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2ip	IDA		Mouse	MGI:MGI:4440768|PMID:20339076
Cellular Component	GO:0000781	chromosome, telomeric region	Terf2ip	IDA		Mouse	PMID:15968270
Cellular Component	GO:0005737	cytoplasm	TERF2IP	IDA		Human	PMID:23178297
Cellular Component	GO:0005737	cytoplasm	Terf2ip	IDA		Mouse	MGI:MGI:4821187|PMID:20622870
Cellular Component	GO:0001673	male germ cell nucleus	Terf2ip	IDA		Mouse	PMID:24062341
Cellular Component	GO:0016604	nuclear body	TERF2IP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000783	nuclear telomere cap complex	TERF2IP	IDA		Human	PMID:15181449
Cellular Component	GO:0000783	nuclear telomere cap complex	TERF2IP	IDA		Human	PMID:16880378
Cellular Component	GO:0005654	nucleoplasm	TERF2IP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TERF2IP	IDA		Human	PMID:17055345
Cellular Component	GO:0005634	nucleus	TERF2IP	IDA		Human	PMID:23178297
Cellular Component	GO:0005634	nucleus	Terf2ip	IDA		Mouse	MGI:MGI:4821187|PMID:20622870
Cellular Component	GO:0070187	shelterin complex	TERF2IP	IPI		Human	PMID:15383534
Cellular Component	GO:0070187	shelterin complex	TERF2IP	IDA		Human	PMID:15383534
Cellular Component	GO:0070187	shelterin complex	TERF2IP	IDA		Human	PMID:21852327
Cellular Component	GO:0070187	shelterin complex	TERF2IP	IDA		Human	PMID:23685356
Biological Process	GO:0048239	negative regulation of DNA recombination at telomere	Terf2ip	IMP		Mouse	MGI:MGI:4440768|PMID:20339076
Biological Process	GO:0048239	negative regulation of DNA recombination at telomere	Terf2ip	IMP		Mouse	MGI:MGI:4839412|PMID:20622869
Biological Process	GO:0001933	negative regulation of protein phosphorylation	TERF2IP	IMP		Human	PMID:23178297
Biological Process	GO:0032205	negative regulation of telomere maintenance	TERF2IP	IDA		Human	PMID:17055345
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Terf2ip	IDA		Mouse	MGI:MGI:4821187|PMID:20622870
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Terf2ip	IMP		Mouse	MGI:MGI:4821187|PMID:20622870
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	TERF2IP	IMP		Human	PMID:23178297
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	TERF2IP	IMP		Human	PMID:23867755
Biological Process	GO:1901985	positive regulation of protein acetylation	TERF2IP	IMP		Human	PMID:23867755
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	TERF2IP	IMP		Human	PMID:17499040
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	TERF2IP	IMP		Human	PMID:17499040
Biological Process	GO:0006355	regulation of DNA-templated transcription	TERF2IP	IMP		Human	PMID:23178297
Biological Process	GO:0006355	regulation of DNA-templated transcription	Terf2ip	IMP		Mouse	MGI:MGI:4839412|PMID:20622869
Biological Process	GO:0010569	regulation of double-strand break repair via homologous recombination	Terf2ip	IMP		Mouse	MGI:MGI:4440768|PMID:20339076
Biological Process	GO:0032204	regulation of telomere maintenance	TERF2IP	IMP		Human	PMID:15100233
Biological Process	GO:0016233	telomere capping	TERF2IP	IDA		Human	PMID:21852327
Biological Process	GO:0000723	telomere maintenance	TERF2IP	IDA		Human	PMID:14565979
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	Terf2ip	IMP		Mouse	MGI:MGI:4440768|PMID:20339076
Biological Process	GO:0010833	telomere maintenance via telomere lengthening	Terf2ip	IMP		Mouse	MGI:MGI:4839412|PMID:20622869

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern