Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TESK2
  • Mouse genes Tesk2
  • Rat genes Tesk2
  • Zfish genes tesk2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tesk2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TESK2	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	TESK2	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Tesk2	IDA		Rat	PMID:11418599|RGD:727318
Cellular Component	GO:0005737	cytoplasm	Tesk2	IDA		Rat	PMID:11418599|RGD:727318
Cellular Component	GO:0016604	nuclear body	TESK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TESK2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Tesk2	IDA		Rat	PMID:11418599|RGD:727318
Biological Process	GO:0030036	actin cytoskeleton organization	Tesk2	IMP		Rat	PMID:11418599|RGD:727318
Biological Process	GO:0048041	focal adhesion assembly	Tesk2	IMP		Rat	PMID:11418599|RGD:727318
Biological Process	GO:0006468	protein phosphorylation	Tesk2	IDA		Rat	PMID:11418599|RGD:727318
Biological Process	GO:0007283	spermatogenesis	Tesk2	IEP		Rat	PMID:10512679|RGD:1357216

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern