Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TET1
  • Mouse genes Tet1
  • Rat genes Tet1
  • Zfish genes tet1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tet1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	TET1	IDA		Human	PMID:19372391
Molecular Function	GO:0005506	iron ion binding	TET1	IDA		Human	PMID:19372391
Molecular Function	GO:0008327	methyl-CpG binding	TET1	IDA		Human	PMID:29276034
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	TET1	IDA		Human	PMID:19372391
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	TET1	IMP		Human	PMID:21496894
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	TET1	IMP		Human	PMID:25284789
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	Tet1	IDA		Mouse	MGI:MGI:3844762|PMID:19372391
Molecular Function	GO:0070579	methylcytosine dioxygenase activity	Tet1	IDA		Mouse	MGI:MGI:5287327|PMID:21778364
Molecular Function	GO:0005515	protein binding	TET1	IPI	UniProtKB:Q86XN7	Human	PMID:34667079
Molecular Function	GO:0005515	protein binding	Tet1	IPI	UniProtKB:Q60520	Mouse	MGI:MGI:5003384|PMID:21490601
Molecular Function	GO:0005515	protein binding	Tet1	IPI	UniProtKB:Q61191|UniProtKB:Q8CGY8	Mouse	MGI:MGI:5487471|PMID:23352454
Molecular Function	GO:0008270	zinc ion binding	TET1	IDA		Human	PMID:29276034
Cellular Component	GO:0005634	nucleus	Tet1	IDA		Mouse	MGI:MGI:3844762|PMID:19372391
Cellular Component	GO:0005634	nucleus	Tet1	IDA		Mouse	PMID:20639862
Biological Process	GO:0071222	cellular response to lipopolysaccharide	tet1	IMP		Zfish	PMID:27418527
Biological Process	GO:0048813	dendrite morphogenesis	Tet1	IMP		Mouse	MGI:MGI:5766415|PMID:26711116
Biological Process	GO:0080111	DNA demethylation	TET1	IMP		Human	PMID:21496894
Biological Process	GO:0080111	DNA demethylation	Tet1	IMP		Mouse	MGI:MGI:5285126|PMID:21496894
Biological Process	GO:0080111	DNA demethylation	Tet1	IMP		Mouse	MGI:MGI:3844762|PMID:19372391
Biological Process	GO:0080111	DNA demethylation	Tet1	IDA		Mouse	PMID:20639862
Biological Process	GO:0001826	inner cell mass cell differentiation	Tet1	IMP		Mouse	MGI:MGI:3844762|PMID:19372391
Biological Process	GO:0001826	inner cell mass cell differentiation	Tet1	IMP		Mouse	PMID:21295276
Biological Process	GO:0001826	inner cell mass cell differentiation	Tet1	IMP		Mouse	PMID:20639862
Biological Process	GO:0090310	negative regulation of DNA methylation-dependent heterochromatin formation	TET1	IMP		Human	PMID:21496894
Biological Process	GO:0008284	positive regulation of cell population proliferation	TET1	IMP		Human	PMID:25284789
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tet1	IMP		Mouse	MGI:MGI:5487471|PMID:23352454
Biological Process	GO:0006493	protein O-linked glycosylation	Tet1	IMP		Mouse	MGI:MGI:5487471|PMID:23352454
Biological Process	GO:0044030	regulation of DNA methylation	Tet1	IMP		Mouse	PMID:21295276
Biological Process	GO:2000653	regulation of genetic imprinting	Tet1	IMP	MGI:MGI:4129024	Mouse	PMID:24291790
Biological Process	GO:0032656	regulation of interleukin-13 production	tet1	IMP		Zfish	PMID:27418527
Biological Process	GO:0001666	response to hypoxia	tet1	IMP	ZFIN:ZDB-GENO-180925-1	Zfish	PMID:29036334
Biological Process	GO:0019827	stem cell population maintenance	Tet1	IMP		Mouse	MGI:MGI:3844762|PMID:19372391

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern