Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tfap2b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TFAP2B
- Mouse genes Tfap2b
- Rat genes Tfap2b
- Zfish genes tfap2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tfap2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Tfap2b	IDA		Rat	PMID:20875861\|RGD:5147969
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	TFAP2B	IDA		Human	PMID:16373396
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	TFAP2B	IDA		Human	PMID:7559606
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Tfap2b	IDA		Mouse	MGI:MGI:5287515\|PMID:21829553
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Tfap2b	IDA		Mouse	PMID:7555706
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TFAP2B	IDA		Human	PMID:11505339
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TFAP2B	IDA		Human	PMID:12169688
Molecular Function	GO:0003700	DNA-binding transcription factor activity	TFAP2B	IDA		Human	PMID:16373396
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	TFAP2B	IDA		Human	PMID:7555706
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Tfap2b	IDA		Mouse	MGI:MGI:5287515\|PMID:21829553
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:Q99967	Human	PMID:11694877
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:P63279	Human	PMID:12072434
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:Q99967-1	Human	PMID:12586840
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:Q719H9	Human	PMID:19115315
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFAP2B	IPI	UniProtKB:Q92481	Human	PMID:7555706
Molecular Function	GO:0005515	protein binding	Tfap2b	IPI	PR:Q6VUP9	Mouse	PMID:14572467
Molecular Function	GO:0005515	protein binding	Tfap2b	IPI	UniProtKB:Q6PGA9	Mouse	PMID:11694877
Molecular Function	GO:0046982	protein heterodimerization activity	TFAP2B	IPI	UniProtKB:Q92481	Human	PMID:11505339
Molecular Function	GO:0042803	protein homodimerization activity	TFAP2B	IPI	UniProtKB:Q92481	Human	PMID:11505339
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	TFAP2B	IDA		Human	PMID:7555706
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tfap2b	IDA		Mouse	MGI:MGI:5287515\|PMID:21829553
Molecular Function	GO:0043565	sequence-specific DNA binding	TFAP2B	IDA		Human	PMID:11505339
Molecular Function	GO:0043565	sequence-specific DNA binding	TFAP2B	IDA		Human	PMID:12169688
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	TFAP2B	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	TFAP2B	IDA		Human	PMID:20607706
Cellular Component	GO:0005634	nucleus	Tfap2b	IDA		Mouse	MGI:MGI:6210177\|PMID:25187989
Cellular Component	GO:0005634	nucleus	Tfap2b	IDA		Rat	PMID:11205881\|RGD:5147970
Biological Process	GO:0035909	aorta morphogenesis	Tfap2b	IMP		Mouse	MGI:MGI:5287515\|PMID:21829553
Biological Process	GO:0051216	cartilage development	tfap2b	IGI	ZFIN:ZDB-GENO-980202-957,ZFIN:ZDB-MRPHLNO-050729-2	Zfish	PMID:15944192
Biological Process	GO:0072044	collecting duct development	Tfap2b	IMP		Mouse	MGI:MGI:2656435\|PMID:12695560
Biological Process	GO:0072017	distal tubule development	Tfap2b	IMP		Mouse	MGI:MGI:2656435\|PMID:12695560
Biological Process	GO:0097070	ductus arteriosus closure	Tfap2b	IMP		Mouse	MGI:MGI:5287515\|PMID:21829553
Biological Process	GO:0097070	ductus arteriosus closure	Tfap2b	IMP		Mouse	PMID:18635823
Biological Process	GO:0045444	fat cell differentiation	TFAP2B	IEP		Human	PMID:16373396
Biological Process	GO:0045444	fat cell differentiation	Tfap2b	IEP		Mouse	MGI:MGI:5294302\|PMID:15940393
Biological Process	GO:0035136	forelimb morphogenesis	Tfap2b	IMP		Mouse	MGI:MGI:5287515\|PMID:21829553
Biological Process	GO:0010467	gene expression	Tfap2b	IMP	MGI:MGI:2180473	Mouse	PMID:18635823
Biological Process	GO:0006006	glucose metabolic process	TFAP2B	IMP		Human	PMID:15940393
Biological Process	GO:0006006	glucose metabolic process	TFAP2B	IMP		Human	PMID:16373396
Biological Process	GO:0006006	glucose metabolic process	TFAP2B	IMP		Human	PMID:19325541
Biological Process	GO:0035137	hindlimb morphogenesis	Tfap2b	IMP		Mouse	MGI:MGI:5287515\|PMID:21829553
Biological Process	GO:0001822	kidney development	Tfap2b	IMP	MGI:MGI:2180473	Mouse	PMID:9271117
Biological Process	GO:0072210	metanephric nephron development	Tfap2b	IEP		Mouse	MGI:MGI:76242\|PMID:7555706
Biological Process	GO:0043066	negative regulation of apoptotic process	TFAP2B	IDA		Human	PMID:17525748
Biological Process	GO:0043066	negative regulation of apoptotic process	Tfap2b	IMP		Mouse	MGI:MGI:5294296\|PMID:17525748
Biological Process	GO:0008285	negative regulation of cell population proliferation	TFAP2B	IDA		Human	PMID:20607706
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	TFAP2B	IDA		Human	PMID:20607706
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Tfap2b	IGI	MGI:MGI:104671	Mouse	PMID:21539825
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TFAP2B	IDA		Human	PMID:7559606
Biological Process	GO:0051402	neuron apoptotic process	Tfap2b	IGI	MGI:MGI:104671	Mouse	PMID:21539825
Biological Process	GO:0008284	positive regulation of cell population proliferation	TFAP2B	IDA		Human	PMID:17525748
Biological Process	GO:0008284	positive regulation of cell population proliferation	Tfap2b	IMP		Mouse	MGI:MGI:5294296\|PMID:17525748
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TFAP2B	IDA		Human	PMID:11505339
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	TFAP2B	IMP		Human	PMID:16373396
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	TFAP2B	IDA		Human	PMID:20607706
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TFAP2B	IDA		Human	PMID:12169688
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	TFAP2B	IDA		Human	PMID:7555706
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tfap2b	IMP		Mouse	MGI:MGI:5287515\|PMID:21829553
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tfap2b	IDA		Mouse	PMID:7555706
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tfap2b	IDA		Mouse	PMID:11694877
Biological Process	GO:0030510	regulation of BMP signaling pathway	Tfap2b	IMP		Mouse	MGI:MGI:5287515\|PMID:21829553
Biological Process	GO:0045595	regulation of cell differentiation	TFAP2B	IDA		Human	PMID:20607706
Biological Process	GO:0050796	regulation of insulin secretion	TFAP2B	IMP		Human	PMID:15940393
Biological Process	GO:0050796	regulation of insulin secretion	TFAP2B	IMP		Human	PMID:19325541
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Tfap2b	IDA		Mouse	MGI:MGI:5287515\|PMID:21829553
Biological Process	GO:0010226	response to lithium ion	Tfap2b	IEP		Rat	PMID:15827566\|RGD:1601546
Biological Process	GO:0009410	response to xenobiotic stimulus	Tfap2b	IEP		Rat	PMID:15663788\|RGD:1601547
Biological Process	GO:0010842	retina layer formation	TFAP2B	IEP		Human	PMID:20607706
Biological Process	GO:0007423	sensory organ development	Tfap2b	IEP		Mouse	MGI:MGI:76242\|PMID:7555706
Biological Process	GO:0043588	skin development	Tfap2b	IEP		Mouse	MGI:MGI:76242\|PMID:7555706
Biological Process	GO:0048745	smooth muscle tissue development	Tfap2b	IMP	MGI:MGI:2180473	Mouse	PMID:18635823
Biological Process	GO:0048485	sympathetic nervous system development	Tfap2b	IGI	MGI:MGI:104671	Mouse	PMID:21539825
Biological Process	GO:0006366	transcription by RNA polymerase II	Tfap2b	IDA		Mouse	PMID:7555706
Biological Process	GO:0006366	transcription by RNA polymerase II	Tfap2b	IDA		Mouse	PMID:11694877

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.