Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TFAP2E
  • Mouse genes Tfap2e
  • Rat genes Tfap2e
  • Zfish genes tfap2e
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tfap2e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Tfap2e	IDA		Mouse	PMID:15305293
Molecular Function	GO:0003677	DNA binding	Tfap2e	IDA		Mouse	PMID:14572467
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Tfap2e	IDA		Mouse	MGI:MGI:2679158|PMID:14572467
Molecular Function	GO:0042802	identical protein binding	Tfap2e	IPI	PR:Q6VUP9	Mouse	PMID:14572467
Molecular Function	GO:0005515	protein binding	Tfap2e	IPI	PR:P34056	Mouse	PMID:14572467
Molecular Function	GO:0005515	protein binding	Tfap2e	IPI	PR:Q61313	Mouse	PMID:14572467
Molecular Function	GO:0005515	protein binding	Tfap2e	IPI	PR:Q61312	Mouse	PMID:14572467
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Tfap2e	IDA		Mouse	MGI:MGI:2679158|PMID:14572467
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	TFAP2E	IDA		Human	PMID:28473536
Biological Process	GO:0030318	melanocyte differentiation	tfap2e	IGI	ZFIN:ZDB-GENO-980202-957,ZFIN:ZDB-MRPHLNO-101013-1	Zfish	PMID:20862309
Biological Process	GO:0030318	melanocyte differentiation	tfap2e	IGI	ZFIN:ZDB-GENO-980202-957,ZFIN:ZDB-MRPHLNO-101013-3	Zfish	PMID:20862309
Biological Process	GO:0030318	melanocyte differentiation	tfap2e	IGI	ZFIN:ZDB-GENO-980202-957,ZFIN:ZDB-MRPHLNO-101013-2	Zfish	PMID:20862309
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Tfap2e	IDA		Mouse	PMID:14572467

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern