Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TGFBI
  • Mouse genes Tgfbi
  • Rat genes Tgfbi
  • Zfish genes tgfbi
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tgfbi

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	TGFBI	IPI	UniProtKB:A8TX70	Human	PMID:19478074
Molecular Function	GO:0050840	extracellular matrix binding	Tgfbi	IDA		Mouse	PMID:18757743
Molecular Function	GO:0042802	identical protein binding	TGFBI	IPI	UniProtKB:Q15582	Human	PMID:31197037
Molecular Function	GO:0005515	protein binding	TGFBI	IPI	UniProtKB:P05107	Human	PMID:18083624
Molecular Function	GO:0005515	protein binding	TGFBI	IPI	UniProtKB:A0A0G2K692	Human	PMID:19478074
Molecular Function	GO:0005515	protein binding	TGFBI	IPI	UniProtKB:Q15063	Human	PMID:19478074
Molecular Function	GO:0005515	protein binding	TGFBI	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TGFBI	IPI	UniProtKB:P05106,UniProtKB:P06756	Human	PMID:25853243
Molecular Function	GO:0005515	protein binding	TGFBI	IPI	UniProtKB:P25815	Human	PMID:32296183
Cellular Component	GO:0005604	basement membrane	Tgfbi	IDA		Rat	PMID:12911551|RGD:1304421
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGFBI	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGFBI	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGFBI	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGFBI	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGFBI	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGFBI	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tgfbi	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tgfbi	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	TGFBI	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	TGFBI	HDA		Human	PMID:21362503
Cellular Component	GO:0031012	extracellular matrix	Tgfbi	IDA		Mouse	PMID:12963107
Cellular Component	GO:0005576	extracellular region	TGFBI	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	TGFBI	IDA		Human	PMID:19478074
Cellular Component	GO:0005615	extracellular space	Tgfbi	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Tgfbi	IDA		Mouse	PMID:12838408
Cellular Component	GO:0005802	trans-Golgi network	TGFBI	IDA		Human	PMID:19478074
Biological Process	GO:0001525	angiogenesis	TGFBI	IEP		Human	PMID:11866539
Biological Process	GO:0007155	cell adhesion	Tgfbi	IDA		Mouse	PMID:12963107
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	tgfbi	IDA		Zfish	PMID:18618001
Biological Process	GO:0002062	chondrocyte differentiation	Tgfbi	IEP		Rat	PMID:16546826|RGD:1599388
Biological Process	GO:0030198	extracellular matrix organization	Tgfbi	IDA		Mouse	PMID:18757743
Biological Process	GO:0051179	localization	TGFBI	IMP		Human	PMID:22640878
Biological Process	GO:0051179	localization	TGFBI	IEP		Human	PMID:25853243
Biological Process	GO:0055001	muscle cell development	tgfbi	IMP	ZFIN:ZDB-MRPHLNO-091007-2	Zfish	PMID:19097068
Biological Process	GO:0055001	muscle cell development	tgfbi	IMP	ZFIN:ZDB-MRPHLNO-091007-1	Zfish	PMID:19097068

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern