Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Tgm2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes TGM2
- Mouse genes Tgm2
- Rat genes Tgm2
- Zfish genes tgm2a,tgm2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tgm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	TGM2	IDA		Human	PMID:23941696
Molecular Function	GO:0005525	GTP binding	TGM2	IDA		Human	PMID:7649299
Molecular Function	GO:0005525	GTP binding	Tgm2	IDA		Rat	PMID:14970202\|RGD:1579990
Molecular Function	GO:0120297	histone dopaminyltransferase activity	TGM2	IDA		Human	PMID:32273471
Molecular Function	GO:0120295	histone serotonyltransferase activity	TGM2	IDA		Human	PMID:30867594
Molecular Function	GO:0042802	identical protein binding	Tgm2	IPI	RGD:621081	Rat	PMID:12469910\|RGD:1580016
Molecular Function	GO:0042802	identical protein binding	Tgm2	IPI	RGD:621081	Rat	PMID:16341586\|RGD:1579955
Molecular Function	GO:0120299	peptide histaminyltransferase activity	TGM2	IDA		Human	PMID:23797785
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:Q12802	Human	PMID:16301118
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:Q04206	Human	PMID:16951195
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P05067:PRO_0000000092	Human	PMID:19542224
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P39060:PRO_0000005794	Human	PMID:19542224
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P02751	Human	PMID:19738201
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P02751	Human	PMID:20080707
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P08727	Human	PMID:20080707
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P40337	Human	PMID:21625219
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P02751	Human	PMID:22442151
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P05067:PRO_0000000092	Human	PMID:28106549
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P28300:PRO_0000018520	Human	PMID:30082873
Molecular Function	GO:0005515	protein binding	TGM2	IPI	UniProtKB:P63241	Human	PMID:9442029
Molecular Function	GO:0005515	protein binding	Tgm2	IPI	RGD:3346	Rat	PMID:16709602\|RGD:2300424
Molecular Function	GO:0019904	protein domain specific binding	Tgm2	IPI	RGD:3346	Rat	PMID:12054611\|RGD:634393
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	TGM2	IDA		Human	PMID:12506096
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	TGM2	IDA		Human	PMID:23941696
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	TGM2	IMP		Human	PMID:24349085
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	TGM2	IMP		Human	PMID:7592956
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	TGM2	IDA		Human	PMID:7649299
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	TGM2	IMP		Human	PMID:8943303
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	TGM2	IDA		Human	PMID:9252372
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	Tgm2	IMP		Mouse	MGI:MGI:1930868\|PMID:11113189
Molecular Function	GO:0003810	protein-glutamine gamma-glutamyltransferase activity	Tgm2	IMP		Mouse	MGI:MGI:3525253\|PMID:11274171
Molecular Function	GO:0050568	protein-glutamine glutaminase activity	TGM2	IDA		Human	PMID:20547769
Molecular Function	GO:0050568	protein-glutamine glutaminase activity	TGM2	IDA		Human	PMID:9623982
Cellular Component	GO:0000785	chromatin	TGM2	IDA		Human	PMID:9575137
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGM2	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGM2	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGM2	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	TGM2	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tgm2	HDA		Mouse	MGI:MGI:6201834\|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Tgm2	HDA		Mouse	MGI:MGI:6201853\|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	Tgm2	IDA		Rat	PMID:7911253\|RGD:8553754
Cellular Component	GO:0005829	cytosol	TGM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	TGM2	IDA		Human	PMID:24349085
Cellular Component	GO:0005829	cytosol	TGM2	IDA		Human	PMID:9575137
Cellular Component	GO:0005829	cytosol	Tgm2	IDA		Rat	PMID:11073883\|RGD:634391
Cellular Component	GO:0070062	extracellular exosome	TGM2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	TGM2	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	TGM2	IDA		Human	PMID:12506096
Cellular Component	GO:0005925	focal adhesion	TGM2	HDA		Human	PMID:21423176
Cellular Component	GO:0005739	mitochondrion	TGM2	IDA		Human	PMID:24349085
Cellular Component	GO:0005739	mitochondrion	Tgm2	IDA		Rat	PMID:16341586\|RGD:1579955
Cellular Component	GO:0000786	nucleosome	TGM2	IDA		Human	PMID:30867594
Cellular Component	GO:0000786	nucleosome	TGM2	IDA		Human	PMID:32273471
Cellular Component	GO:0005634	nucleus	TGM2	IDA		Human	PMID:9575137
Cellular Component	GO:0005634	nucleus	Tgm2	IDA		Rat	PMID:11073883\|RGD:634391
Cellular Component	GO:0005886	plasma membrane	TGM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	TGM2	IDA		Human	PMID:2578891
Cellular Component	GO:0005886	plasma membrane	TGM2	IMP		Human	PMID:8105889
Cellular Component	GO:0005886	plasma membrane	Tgm2	IDA		Rat	PMID:14970202\|RGD:1579990
Biological Process	GO:0043277	apoptotic cell clearance	TGM2	IDA		Human	PMID:19628791
Biological Process	GO:0001974	blood vessel remodeling	Tgm2	IMP		Rat	PMID:15550691\|RGD:1579986
Biological Process	GO:0060445	branching involved in salivary gland morphogenesis	Tgm2	IMP		Mouse	PMID:15970210
Biological Process	GO:0071314	cellular response to cocaine	TGM2	IDA		Human	PMID:32273471
Biological Process	GO:1903351	cellular response to dopamine	TGM2	IDA		Human	PMID:32273471
Biological Process	GO:1904015	cellular response to serotonin	TGM2	IDA		Human	PMID:30867594
Biological Process	GO:0014046	dopamine secretion	TGM2	IDA		Human	PMID:32273471
Biological Process	GO:0010467	gene expression	TGM2	IDA		Human	PMID:30867594
Biological Process	GO:0018153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	Tgm2	IDA		Rat	PMID:16341586\|RGD:1579955
Biological Process	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration	TGM2	IMP		Human	PMID:24349085
Biological Process	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration	Tgm2	IMP		Mouse	MGI:MGI:5574435\|PMID:24349085
Biological Process	GO:0018149	peptide cross-linking	TGM2	IDA		Human	PMID:12506096
Biological Process	GO:0018149	peptide cross-linking	TGM2	IDA		Human	PMID:23941696
Biological Process	GO:0018149	peptide cross-linking	TGM2	IDA		Human	PMID:30458214
Biological Process	GO:0018149	peptide cross-linking	TGM2	IDA		Human	PMID:9252372
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	TGM2	IMP		Human	PMID:7592956
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	TGM2	IMP		Human	PMID:8943303
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Tgm2	IDA		Rat	PMID:7911253\|RGD:8553754
Biological Process	GO:0043065	positive regulation of apoptotic process	TGM2	IMP		Human	PMID:24349085
Biological Process	GO:0043065	positive regulation of apoptotic process	Tgm2	IMP		Rat	PMID:11073883\|RGD:634391
Biological Process	GO:0045785	positive regulation of cell adhesion	Tgm2	IMP		Mouse	MGI:MGI:3525253\|PMID:11274171
Biological Process	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	Tgm2	IMP		Rat	PMID:12054611\|RGD:634393
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Tgm2	IMP		Rat	PMID:15471861\|RGD:1579987
Biological Process	GO:0050729	positive regulation of inflammatory response	Tgm2	IMP		Rat	PMID:15471861\|RGD:1579987
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	TGM2	IMP		Human	PMID:24349085
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	Tgm2	IMP		Mouse	MGI:MGI:5574435\|PMID:24349085
Biological Process	GO:0050769	positive regulation of neurogenesis	TGM2	IDA		Human	PMID:30867594
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Tgm2	IDA		Rat	PMID:14970202\|RGD:1579990
Biological Process	GO:0018277	protein deamination	TGM2	IDA		Human	PMID:20547769
Biological Process	GO:0018277	protein deamination	TGM2	IDA		Human	PMID:9623982
Biological Process	GO:2000425	regulation of apoptotic cell clearance	TGM2	IDA		Human	PMID:7935379
Biological Process	GO:2000425	regulation of apoptotic cell clearance	Tgm2	IMP		Mouse	MGI:MGI:3580951\|PMID:15905580
Biological Process	GO:2000425	regulation of apoptotic cell clearance	Tgm2	IMP		Mouse	MGI:MGI:3629478\|PMID:12810961
Biological Process	GO:0042981	regulation of apoptotic process	TGM2	IDA		Human	PMID:9252372
Biological Process	GO:0060662	salivary gland cavitation	Tgm2	IMP		Mouse	PMID:15970210

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.