Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THAP11
  • Mouse genes Thap11
  • Rat genes Thap11
  • Zfish genes thap11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thap11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	THAP11	IDA		Human	PMID:23306615
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	THAP11	IDA		Human	PMID:19008924
Molecular Function	GO:0005515	protein binding	THAP11	IPI	UniProtKB:P51610	Human	PMID:18585351
Molecular Function	GO:0005515	protein binding	THAP11	IPI	UniProtKB:P70677	Human	PMID:18585351
Molecular Function	GO:0005515	protein binding	THAP11	IPI	UniProtKB:Q13363	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	THAP11	IPI	UniProtKB:Q15365	Human	PMID:22673507
Molecular Function	GO:0005515	protein binding	THAP11	IPI	UniProtKB:Q8N1B4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP11	IPI	UniProtKB:Q13363	Human	PMID:31041561
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	THAP11	IDA		Human	PMID:19008924
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175
Molecular Function	GO:0008270	zinc ion binding	THAP11	IDA		Human	PMID:23306615
Cellular Component	GO:0005829	cytosol	THAP11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	THAP11	IDA		Human	GO_REF:0000052
Biological Process	GO:0008283	cell population proliferation	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175
Biological Process	GO:0022900	electron transport chain	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	THAP11	IDA		Human	PMID:19008924
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175
Biological Process	GO:0030182	neuron differentiation	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175
Biological Process	GO:2000825	positive regulation of androgen receptor activity	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175
Biological Process	GO:1903108	regulation of mitochondrial transcription	Thap11	IMP	MGI:MGI:3052237,MGI:MGI:3797582	Mouse	PMID:26876175

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern