Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THBS3
  • Mouse genes Thbs3
  • Rat genes Thbs3
  • Zfish genes thbs3a,thbs3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thbs3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	THBS3	IDA		Human	PMID:8288588
Molecular Function	GO:0005515	protein binding	THBS3	IPI	UniProtKB:P27797	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THBS3	IPI	UniProtKB:P36957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THBS3	IPI	UniProtKB:Q8TDX7	Human	PMID:32814053
Cellular Component	GO:0062023	collagen-containing extracellular matrix	THBS3	HDA		Human	PMID:28327460
Cellular Component	GO:0048471	perinuclear region of cytoplasm	THBS3	IDA		Human	PMID:11943589
Biological Process	GO:0060346	bone trabecula formation	Thbs3	IMP	MGI:MGI:3581964	Mouse	PMID:15964815
Biological Process	GO:0003417	growth plate cartilage development	Thbs3	IMP	MGI:MGI:3581964	Mouse	PMID:18467703
Biological Process	GO:0003417	growth plate cartilage development	Thbs3	IGI	MGI:MGI:88465	Mouse	PMID:18467703
Biological Process	GO:0003417	growth plate cartilage development	Thbs3	IGI	MGI:MGI:88469	Mouse	PMID:18467703
Biological Process	GO:0003417	growth plate cartilage development	Thbs3	IGI	MGI:MGI:98737	Mouse	PMID:18467703
Biological Process	GO:0060231	mesenchymal to epithelial transition	thbs3a	IGI	ZFIN:ZDB-GENE-020102-1	Zfish	PMID:28701377
Biological Process	GO:0043931	ossification involved in bone maturation	Thbs3	IMP	MGI:MGI:3581964	Mouse	PMID:15964815
Biological Process	GO:0061053	somite development	thbs3a	IGI	ZFIN:ZDB-GENE-020102-1	Zfish	PMID:28701377

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern