Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THOC2
  • Mouse genes Thoc2
  • Rat genes Thoc2
  • Zfish genes thoc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thoc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003729	mRNA binding	Thoc2	IMP		Mouse	PMID:24315442
Molecular Function	GO:0005515	protein binding	THOC2	IPI	UniProtKB:Q96FV9	Human	PMID:15870275
Molecular Function	GO:0005515	protein binding	THOC2	IPI	UniProtKB:O75152	Human	PMID:22928037
Molecular Function	GO:0005515	protein binding	THOC2	IPI	UniProtKB:Q9BY77	Human	PMID:22928037
Molecular Function	GO:0005515	protein binding	Thoc2	IPI	PR:Q8BKT7	Mouse	PMID:24315442
Molecular Function	GO:0005515	protein binding	Thoc2	IPI	PR:Q7TMY4	Mouse	PMID:24315442
Molecular Function	GO:0005515	protein binding	Thoc2	IPI	PR:Q8VE80	Mouse	PMID:24315442
Molecular Function	GO:0005515	protein binding	Thoc2	IPI	PR:Q8R3N6	Mouse	PMID:24315442
Molecular Function	GO:0005515	protein binding	Thoc2	IPI	PR:Q5U4D9	Mouse	PMID:24315442
Cellular Component	GO:0000781	chromosome, telomeric region	THOC2	IDA		Human	PMID:24270157
Cellular Component	GO:0005634	nucleus	Thoc2	IDA		Mouse	PMID:24315442
Cellular Component	GO:0000347	THO complex	THOC2	IDA		Human	PMID:15998806
Cellular Component	GO:0000445	THO complex part of transcription export complex	THOC2	IDA		Human	PMID:15998806
Cellular Component	GO:0000346	transcription export complex	THOC2	IDA		Human	PMID:15833825
Cellular Component	GO:0000346	transcription export complex	THOC2	IDA		Human	PMID:15998806
Biological Process	GO:0001824	blastocyst development	Thoc2	IMP		Mouse	PMID:24315442
Biological Process	GO:0000902	cell morphogenesis	Thoc2	IMP		Mouse	PMID:24315442
Biological Process	GO:0048699	generation of neurons	THOC2	IMP		Human	PMID:26166480
Biological Process	GO:0006406	mRNA export from nucleus	THOC2	IDA		Human	PMID:17190602
Biological Process	GO:0010977	negative regulation of neuron projection development	Thoc2	IMP		Rat	PMID:23749989|RGD:10413914
Biological Process	GO:0048666	neuron development	THOC2	IMP		Human	PMID:26166480
Biological Process	GO:0016973	poly(A)+ mRNA export from nucleus	THOC2	IDA		Human	PMID:22928037
Biological Process	GO:0010468	regulation of gene expression	Thoc2	IMP		Mouse	PMID:24315442
Biological Process	GO:0010793	regulation of mRNA export from nucleus	Thoc2	IMP		Mouse	PMID:24315442
Biological Process	GO:0017145	stem cell division	Thoc2	IMP		Mouse	PMID:24315442
Biological Process	GO:0046784	viral mRNA export from host cell nucleus	THOC2	IDA		Human	PMID:18974867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern