Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THOC5
  • Mouse genes Thoc5
  • Rat genes Thoc5
  • Zfish genes thoc5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thoc5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003729	mRNA binding	Thoc5	IMP		Mouse	PMID:24315442
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q6I9Y2	Human	PMID:19059247
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q96FV9	Human	PMID:19059247
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q03518	Human	PMID:19165146
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q86V81	Human	PMID:19165146
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q96FV9	Human	PMID:19165146
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q9UBU9	Human	PMID:19165146
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q96FV9	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q96FV9	Human	PMID:23299939
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q53F19	Human	PMID:26382858
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q6I9Y2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q96FV9	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	THOC5	IPI	UniProtKB:Q96FV9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Thoc5	IPI	PR:P09581	Mouse	PMID:10597251
Molecular Function	GO:0005515	protein binding	Thoc5	IPI	PR:B1AZI6	Mouse	PMID:24315442
Cellular Component	GO:0000781	chromosome, telomeric region	THOC5	IDA		Human	PMID:24270157
Cellular Component	GO:0005654	nucleoplasm	THOC5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	THOC5	IDA		Human	PMID:19059247
Cellular Component	GO:0005634	nucleus	Thoc5	IMP		Mouse	MGI:MGI:5619485|PMID:15221008
Cellular Component	GO:0005634	nucleus	Thoc5	IDA		Mouse	PMID:24315442
Cellular Component	GO:0000347	THO complex	THOC5	IDA		Human	PMID:15998806
Cellular Component	GO:0000445	THO complex part of transcription export complex	THOC5	IDA		Human	PMID:15998806
Cellular Component	GO:0000346	transcription export complex	THOC5	IDA		Human	PMID:15833825
Cellular Component	GO:0000346	transcription export complex	THOC5	IDA		Human	PMID:15998806
Biological Process	GO:0001824	blastocyst development	Thoc5	IMP		Mouse	PMID:24315442
Biological Process	GO:0000902	cell morphogenesis	Thoc5	IMP		Mouse	PMID:24315442
Biological Process	GO:0030224	monocyte differentiation	THOC5	IDA		Human	PMID:19015024
Biological Process	GO:0006406	mRNA export from nucleus	THOC5	IDA		Human	PMID:17190602
Biological Process	GO:2000002	negative regulation of DNA damage checkpoint	THOC5	IMP		Human	PMID:22144908
Biological Process	GO:0045650	negative regulation of macrophage differentiation	Thoc5	IDA		Mouse	PMID:10597251
Biological Process	GO:0032786	positive regulation of DNA-templated transcription, elongation	THOC5	IMP		Human	PMID:22144908
Biological Process	GO:0060215	primitive hemopoiesis	Thoc5	IMP		Mouse	MGI:MGI:4943620|PMID:20051105
Biological Process	GO:0010468	regulation of gene expression	Thoc5	IMP		Mouse	PMID:24315442
Biological Process	GO:0010793	regulation of mRNA export from nucleus	Thoc5	IMP		Mouse	PMID:24315442
Biological Process	GO:2000035	regulation of stem cell division	Thoc5	IMP		Mouse	PMID:24315442
Biological Process	GO:0017145	stem cell division	Thoc5	IMP		Mouse	PMID:24315442
Biological Process	GO:0046784	viral mRNA export from host cell nucleus	THOC5	IDA		Human	PMID:18974867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern