Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THOP1
  • Mouse genes Thop1
  • Rat genes Thop1
  • Zfish genes thop1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thop1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004222	metalloendopeptidase activity	Thop1	IDA		Mouse	PMID:10969067
Molecular Function	GO:0008233	peptidase activity	Thop1	IDA		Rat	PMID:12500972|RGD:152025518
Molecular Function	GO:0008233	peptidase activity	Thop1	IDA		Rat	PMID:8702598|RGD:1625498
Molecular Function	GO:0042277	peptide binding	Thop1	IDA		Rat	PMID:8702598|RGD:1625498
Molecular Function	GO:0005515	protein binding	THOP1	IPI	UniProtKB:O95208-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THOP1	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Biological Process	GO:0035556	intracellular signal transduction	Thop1	IDA		Mouse	PMID:10969067
Biological Process	GO:0043171	peptide catabolic process	Thop1	IDA		Rat	PMID:12500972|RGD:152025518
Biological Process	GO:0006518	peptide metabolic process	Thop1	IDA		Mouse	PMID:10969067

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern