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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Thy1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thy1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0019899enzyme bindingThy1IPIRGD:621017RatPMID:8666426|RGD:2303643
Molecular FunctionGO:0034235GPI anchor bindingThy1IDARatPMID:16257296|RGD:8554003
Molecular FunctionGO:0005096GTPase activator activityThy1IDARatPMID:15093746|RGD:8553684
Molecular FunctionGO:0005178integrin bindingTHY1IPIUniProtKB:P11215HumanPMID:15004192
Molecular FunctionGO:0005178integrin bindingTHY1IMPHumanPMID:18346467
Molecular FunctionGO:0005178integrin bindingThy1IMPMouseMGI:MGI:3796911|PMID:18346467
Molecular FunctionGO:0005178integrin bindingThy1IMPMouseMGI:MGI:5882873|PMID:22479590
Molecular FunctionGO:0005515protein bindingTHY1IPIUniProtKB:P48960HumanPMID:22210915
Molecular FunctionGO:0005515protein bindingTHY1IPIUniProtKB:P05067HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingTHY1IPIUniProtKB:P06239HumanPMID:7513706
Molecular FunctionGO:0005515protein bindingThy1IPIRGD:69355RatPMID:10814697|RGD:1643027
Molecular FunctionGO:0005515protein bindingThy1IPIUniProtKB:P05106RatPMID:11470407|RGD:8553359
Molecular FunctionGO:0019901protein kinase bindingThy1IPIRGD:2641RatPMID:8870703|RGD:2303644
Cellular ComponentGO:0016324apical plasma membraneTHY1IDAHumanPMID:14757759
Cellular ComponentGO:0030673axolemmaThy1IDARatPMID:22479590|RGD:12793046
Cellular ComponentGO:0009986cell surfaceTHY1IDAHumanPMID:9749990
Cellular ComponentGO:0009986cell surfaceThy1IDARatPMID:15474526|RGD:151665813
Cellular ComponentGO:0009986cell surfaceThy1IDARatPMID:22479590|RGD:12793046
Cellular ComponentGO:0009986cell surfaceThy1IDARatPMID:31723344|RGD:152176657
Cellular ComponentGO:0005829cytosolThy1IDARatPMID:15547945|RGD:8554523
Cellular ComponentGO:0030425dendriteThy1IDAMousePMID:15677725
Cellular ComponentGO:0032590dendrite membraneThy1IDARatPMID:22479590|RGD:12793046
Cellular ComponentGO:0005783endoplasmic reticulumTHY1IDAHumanGO_REF:0000054
Cellular ComponentGO:0009897external side of plasma membraneThy1IDAMouseMGI:MGI:67656|PMID:7983148
Cellular ComponentGO:0009897external side of plasma membraneThy1IDAMousePMID:17082577
Cellular ComponentGO:0009897external side of plasma membraneThy1IDAMousePMID:24029230
Cellular ComponentGO:0009897external side of plasma membraneThy1IDAMousePMID:14707049
Cellular ComponentGO:0009897external side of plasma membraneThy1IDAMousePMID:16455951
Cellular ComponentGO:0009897external side of plasma membraneThy1IDAMousePMID:10567740
Cellular ComponentGO:0070062extracellular exosomeTHY1HDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular exosomeTHY1HDAHumanPMID:23533145
Cellular ComponentGO:0005925focal adhesionTHY1HDAHumanPMID:21423176
Cellular ComponentGO:0030426growth coneThy1IDARatPMID:10601014|RGD:8554398
Cellular ComponentGO:0045121membrane raftThy1IDAMousePMID:17341485
Cellular ComponentGO:0045121membrane raftThy1IDARatPMID:14499952|RGD:12793007
Cellular ComponentGO:0043209myelin sheathThy1HDAMouseMGI:MGI:3834050|PMID:17634366
Cellular ComponentGO:0032809neuronal cell body membraneThy1IDARatPMID:22479590|RGD:12793046
Cellular ComponentGO:0005886plasma membraneThy1IDARatPMID:15547945|RGD:8554523
Biological ProcessGO:0001525angiogenesisThy1IDAMouseMGI:MGI:3687715|PMID:9576104
Biological ProcessGO:0098609cell-cell adhesionThy1IMPRatPMID:9285719|RGD:8554466
Biological ProcessGO:0007267cell-cell signalingThy1IDAMouseMGI:MGI:5882873|PMID:22479590
Biological ProcessGO:0007267cell-cell signalingThy1IDARatPMID:22479590|RGD:12793046
Biological ProcessGO:0007010cytoskeleton organizationThy1IDARatPMID:15093746|RGD:8553684
Biological ProcessGO:0048041focal adhesion assemblyThy1IDARatPMID:15093746|RGD:8553684
Biological ProcessGO:0007229integrin-mediated signaling pathwayTHY1IMPHumanPMID:18346467
Biological ProcessGO:0007229integrin-mediated signaling pathwayThy1IMPMouseMGI:MGI:3796911|PMID:18346467
Biological ProcessGO:0050771negative regulation of axonogenesisThy1IDARatPMID:15547945|RGD:8554523
Biological ProcessGO:0030336negative regulation of cell migrationThy1IDARatPMID:15093746|RGD:8553684
Biological ProcessGO:0070571negative regulation of neuron projection regenerationThy1IMPMouseMGI:MGI:5882873|PMID:22479590
Biological ProcessGO:0070571negative regulation of neuron projection regenerationThy1IMPRatPMID:22479590|RGD:12793046
Biological ProcessGO:0006469negative regulation of protein kinase activityThy1IDARatPMID:15093746|RGD:8553684
Biological ProcessGO:0061099negative regulation of protein tyrosine kinase activityThy1IDARatPMID:22479590|RGD:12793046
Biological ProcessGO:0050860negative regulation of T cell receptor signaling pathwayThy1IDAMouseMGI:MGI:1096761|PMID:9285719
Biological ProcessGO:0002693positive regulation of cellular extravasationTHY1IDAHumanPMID:15004192
Biological ProcessGO:0051894positive regulation of focal adhesion assemblyTHY1IMPHumanPMID:18346467
Biological ProcessGO:0051894positive regulation of focal adhesion assemblyThy1IMPMouseMGI:MGI:3796911|PMID:18346467
Biological ProcessGO:0043547positive regulation of GTPase activityThy1IDARatPMID:15093746|RGD:8553684
Biological ProcessGO:0034116positive regulation of heterotypic cell-cell adhesionTHY1IDAHumanPMID:15004192
Biological ProcessGO:0051281positive regulation of release of sequestered calcium ion into cytosolThy1IDARatPMID:2873512|RGD:8554039
Biological ProcessGO:0050870positive regulation of T cell activationThy1IDARatPMID:7722293|RGD:8553490
Biological ProcessGO:0046777protein autophosphorylationThy1IDARatPMID:19723805|RGD:10047344
Biological ProcessGO:0043113receptor clusteringThy1IDARatPMID:22479590|RGD:12793046
Biological ProcessGO:0001952regulation of cell-matrix adhesionTHY1IMPHumanPMID:9749990
Biological ProcessGO:2000298regulation of Rho-dependent protein serine/threonine kinase activityThy1IDAMouseMGI:MGI:3796911|PMID:18346467
Biological ProcessGO:0048678response to axon injuryThy1IEPRatPMID:20187850|RGD:151665810
Biological ProcessGO:0046549retinal cone cell developmentThy1IMPMouseMGI:MGI:1349255|PMID:10567740
Biological ProcessGO:0050852T cell receptor signaling pathwayThy1IMPRatPMID:9285719|RGD:8554466

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory