Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Thy1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes THY1
- Mouse genes Thy1
- Rat genes Thy1
- Zfish genes thy1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thy1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Thy1	IPI	RGD:621017	Rat	PMID:8666426\|RGD:2303643
Molecular Function	GO:0034235	GPI anchor binding	Thy1	IDA		Rat	PMID:16257296\|RGD:8554003
Molecular Function	GO:0005096	GTPase activator activity	Thy1	IDA		Rat	PMID:15093746\|RGD:8553684
Molecular Function	GO:0005178	integrin binding	THY1	IPI	UniProtKB:P11215	Human	PMID:15004192
Molecular Function	GO:0005178	integrin binding	THY1	IMP		Human	PMID:18346467
Molecular Function	GO:0005178	integrin binding	Thy1	IMP		Mouse	MGI:MGI:3796911\|PMID:18346467
Molecular Function	GO:0005178	integrin binding	Thy1	IMP		Mouse	MGI:MGI:5882873\|PMID:22479590
Molecular Function	GO:0005515	protein binding	THY1	IPI	UniProtKB:P48960	Human	PMID:22210915
Molecular Function	GO:0005515	protein binding	THY1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THY1	IPI	UniProtKB:P06239	Human	PMID:7513706
Molecular Function	GO:0005515	protein binding	Thy1	IPI	RGD:69355	Rat	PMID:10814697\|RGD:1643027
Molecular Function	GO:0005515	protein binding	Thy1	IPI	UniProtKB:P05106	Rat	PMID:11470407\|RGD:8553359
Molecular Function	GO:0019901	protein kinase binding	Thy1	IPI	RGD:2641	Rat	PMID:8870703\|RGD:2303644
Cellular Component	GO:0016324	apical plasma membrane	THY1	IDA		Human	PMID:14757759
Cellular Component	GO:0030673	axolemma	Thy1	IDA		Rat	PMID:22479590\|RGD:12793046
Cellular Component	GO:0009986	cell surface	THY1	IDA		Human	PMID:9749990
Cellular Component	GO:0009986	cell surface	Thy1	IDA		Rat	PMID:15474526\|RGD:151665813
Cellular Component	GO:0009986	cell surface	Thy1	IDA		Rat	PMID:22479590\|RGD:12793046
Cellular Component	GO:0009986	cell surface	Thy1	IDA		Rat	PMID:31723344\|RGD:152176657
Cellular Component	GO:0005829	cytosol	Thy1	IDA		Rat	PMID:15547945\|RGD:8554523
Cellular Component	GO:0030425	dendrite	Thy1	IDA		Mouse	PMID:15677725
Cellular Component	GO:0032590	dendrite membrane	Thy1	IDA		Rat	PMID:22479590\|RGD:12793046
Cellular Component	GO:0005783	endoplasmic reticulum	THY1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0009897	external side of plasma membrane	Thy1	IDA		Mouse	MGI:MGI:67656\|PMID:7983148
Cellular Component	GO:0009897	external side of plasma membrane	Thy1	IDA		Mouse	PMID:17082577
Cellular Component	GO:0009897	external side of plasma membrane	Thy1	IDA		Mouse	PMID:24029230
Cellular Component	GO:0009897	external side of plasma membrane	Thy1	IDA		Mouse	PMID:14707049
Cellular Component	GO:0009897	external side of plasma membrane	Thy1	IDA		Mouse	PMID:16455951
Cellular Component	GO:0009897	external side of plasma membrane	Thy1	IDA		Mouse	PMID:10567740
Cellular Component	GO:0070062	extracellular exosome	THY1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	THY1	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	THY1	HDA		Human	PMID:21423176
Cellular Component	GO:0030426	growth cone	Thy1	IDA		Rat	PMID:10601014\|RGD:8554398
Cellular Component	GO:0045121	membrane raft	Thy1	IDA		Mouse	PMID:17341485
Cellular Component	GO:0045121	membrane raft	Thy1	IDA		Rat	PMID:14499952\|RGD:12793007
Cellular Component	GO:0043209	myelin sheath	Thy1	HDA		Mouse	MGI:MGI:3834050\|PMID:17634366
Cellular Component	GO:0032809	neuronal cell body membrane	Thy1	IDA		Rat	PMID:22479590\|RGD:12793046
Cellular Component	GO:0005886	plasma membrane	Thy1	IDA		Rat	PMID:15547945\|RGD:8554523
Biological Process	GO:0001525	angiogenesis	Thy1	IDA		Mouse	MGI:MGI:3687715\|PMID:9576104
Biological Process	GO:0098609	cell-cell adhesion	Thy1	IMP		Rat	PMID:9285719\|RGD:8554466
Biological Process	GO:0007267	cell-cell signaling	Thy1	IDA		Mouse	MGI:MGI:5882873\|PMID:22479590
Biological Process	GO:0007267	cell-cell signaling	Thy1	IDA		Rat	PMID:22479590\|RGD:12793046
Biological Process	GO:0007010	cytoskeleton organization	Thy1	IDA		Rat	PMID:15093746\|RGD:8553684
Biological Process	GO:0048041	focal adhesion assembly	Thy1	IDA		Rat	PMID:15093746\|RGD:8553684
Biological Process	GO:0007229	integrin-mediated signaling pathway	THY1	IMP		Human	PMID:18346467
Biological Process	GO:0007229	integrin-mediated signaling pathway	Thy1	IMP		Mouse	MGI:MGI:3796911\|PMID:18346467
Biological Process	GO:0050771	negative regulation of axonogenesis	Thy1	IDA		Rat	PMID:15547945\|RGD:8554523
Biological Process	GO:0030336	negative regulation of cell migration	Thy1	IDA		Rat	PMID:15093746\|RGD:8553684
Biological Process	GO:0070571	negative regulation of neuron projection regeneration	Thy1	IMP		Mouse	MGI:MGI:5882873\|PMID:22479590
Biological Process	GO:0070571	negative regulation of neuron projection regeneration	Thy1	IMP		Rat	PMID:22479590\|RGD:12793046
Biological Process	GO:0006469	negative regulation of protein kinase activity	Thy1	IDA		Rat	PMID:15093746\|RGD:8553684
Biological Process	GO:0061099	negative regulation of protein tyrosine kinase activity	Thy1	IDA		Rat	PMID:22479590\|RGD:12793046
Biological Process	GO:0050860	negative regulation of T cell receptor signaling pathway	Thy1	IDA		Mouse	MGI:MGI:1096761\|PMID:9285719
Biological Process	GO:0002693	positive regulation of cellular extravasation	THY1	IDA		Human	PMID:15004192
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	THY1	IMP		Human	PMID:18346467
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	Thy1	IMP		Mouse	MGI:MGI:3796911\|PMID:18346467
Biological Process	GO:0043547	positive regulation of GTPase activity	Thy1	IDA		Rat	PMID:15093746\|RGD:8553684
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	THY1	IDA		Human	PMID:15004192
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	Thy1	IDA		Rat	PMID:2873512\|RGD:8554039
Biological Process	GO:0050870	positive regulation of T cell activation	Thy1	IDA		Rat	PMID:7722293\|RGD:8553490
Biological Process	GO:0046777	protein autophosphorylation	Thy1	IDA		Rat	PMID:19723805\|RGD:10047344
Biological Process	GO:0043113	receptor clustering	Thy1	IDA		Rat	PMID:22479590\|RGD:12793046
Biological Process	GO:0001952	regulation of cell-matrix adhesion	THY1	IMP		Human	PMID:9749990
Biological Process	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity	Thy1	IDA		Mouse	MGI:MGI:3796911\|PMID:18346467
Biological Process	GO:0048678	response to axon injury	Thy1	IEP		Rat	PMID:20187850\|RGD:151665810
Biological Process	GO:0046549	retinal cone cell development	Thy1	IMP		Mouse	MGI:MGI:1349255\|PMID:10567740
Biological Process	GO:0050852	T cell receptor signaling pathway	Thy1	IMP		Rat	PMID:9285719\|RGD:8554466

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 06/12/2024 MGI 6.13

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.