Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TIAL1
  • Mouse genes Tial1
  • Rat genes Tial1
  • Zfish genes tial1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tial1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	Tial1	IDA		Mouse	PMID:10921895
Molecular Function	GO:0003730	mRNA 3'-UTR binding	TIAL1	IDA		Human	PMID:33203680
Molecular Function	GO:0005515	protein binding	TIAL1	IPI	UniProtKB:Q9HCE1	Human	PMID:34517762
Molecular Function	GO:0005515	protein binding	Tial1	IPI	UniProtKB:Q3THB3|UniProtKB:Q6PDM2|UniProtKB:Q8K2L4	Mouse	MGI:MGI:5508562|PMID:20477871
Molecular Function	GO:0140517	protein-RNA adaptor activity	TIAL1	IDA		Human	PMID:33203680
Molecular Function	GO:0003723	RNA binding	TIAL1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	TIAL1	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	Tial1	IDA		Mouse	MGI:MGI:4820495|PMID:19861488
Cellular Component	GO:0005737	cytoplasm	Tial1	IDA		Mouse	PMID:16278295
Cellular Component	GO:0010494	cytoplasmic stress granule	Tial1	IDA		Mouse	MGI:MGI:4820495|PMID:19861488
Cellular Component	GO:0010494	cytoplasmic stress granule	Tial1	IDA		Mouse	MGI:MGI:4397616|PMID:19825938
Cellular Component	GO:0010494	cytoplasmic stress granule	Tial1	IDA		Rat	PMID:22555848|RGD:10059425
Cellular Component	GO:0005829	cytosol	TIAL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TIAL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Tial1	IDA		Mouse	MGI:MGI:4820495|PMID:19861488
Cellular Component	GO:0005634	nucleus	Tial1	IDA		Mouse	MGI:MGI:4397616|PMID:19825938
Cellular Component	GO:0005634	nucleus	Tial1	IDA		Mouse	PMID:9482885
Cellular Component	GO:0005634	nucleus	Tial1	IDA		Mouse	PMID:16278295
Cellular Component	GO:0005634	nucleus	Tial1	IDA		Rat	PMID:12855701|RGD:10059306
Cellular Component	GO:1990904	ribonucleoprotein complex	Tial1	IDA		Rat	PMID:12855701|RGD:10059306
Biological Process	GO:0007281	germ cell development	Tial1	IMP	MGI:MGI:2660803	Mouse	PMID:9482885
Biological Process	GO:0008285	negative regulation of cell population proliferation	TIAL1	IMP		Human	PMID:33203680
Biological Process	GO:0035332	positive regulation of hippo signaling	TIAL1	IMP		Human	PMID:33203680
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	TIAL1	IGI	FB:FBgn0005649	Human	PMID:33203680
Biological Process	GO:2000648	positive regulation of stem cell proliferation	Tial1	IMP	MGI:MGI:2660803	Mouse	PMID:9482885
Biological Process	GO:0017145	stem cell division	Tial1	IMP	MGI:MGI:2660803	Mouse	PMID:9482885
Biological Process	GO:0072089	stem cell proliferation	Tial1	IMP	MGI:MGI:2660803	Mouse	PMID:9482885

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern